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OT: Daily Covid thread 9/24

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Or. The insane policy of sending infected people into nursing homes increased the death rate by 3 times other states. After all this was done in both N.Y. and NJ. It’s almost as if Cuomo and Murphy we’re trying to kill more people.
Nope, fake news, but why would they have been worried, it was 15 cases soon to be zero and nothing more than the flu we don't shut down nursing homes for a little flu!!
 
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Nope it's called inadequate testing at the start of the pandemic resulting in many missed cases.
Nope. NY didn't follow their chicomvirus infection models or implement sentinel testing. West Coast cities and states hit at the same time, did. This has already been discussed. Keep up.
 
Or. The insane policy of sending infected people into nursing homes increased the death rate by 3 times other states. After all this was done in both N.Y. and NJ. It’s almost as if Cuomo and Murphy we’re trying to kill more people.

raw
 
Not wearing a mask can be hazardous to one's health:



But, when the cop approached the woman and told her she needed to wear her mask, cops say she told the cop she had asthma and continually refused to wear her mask.
The cop told the woman she would have to leave and wait outside the stadium but she refused … leading to being tased once and her arrest for criminal trespassing.


 
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Sanofi news:

While Sanofi’s development timeline is slightly behind other drugmakers such as Moderna and Pfizer, which have commenced large-scale human trials, Hudson said he was confident in the tried-and-true process the company is operating. Even before the Covid-19 pandemic, the company supplied around 1 billion doses of vaccines for other infectious diseases across the world, Hudson noted.

“Hundreds of millions of influenza doses, meningitis, yellow fever, rabies — we simply know what we’re doing,” he said. “And that’s why we’re excited about our approach in Covid-19. Let’s be frank: we’re using a platform that we use every year, so we know how to do it. We know what to do, and we’re moving at speed.”

As for when Sanofi’s vaccine candidates could be available to the public, should it prove safe and effective, Hudson said: “We’re already in human studies. We’re manufacturing doses pretty much right now, and we’ll be available some point early next year.”
 
Sanofi news:

While Sanofi’s development timeline is slightly behind other drugmakers such as Moderna and Pfizer, which have commenced large-scale human trials, Hudson said he was confident in the tried-and-true process the company is operating. Even before the Covid-19 pandemic, the company supplied around 1 billion doses of vaccines for other infectious diseases across the world, Hudson noted.

“Hundreds of millions of influenza doses, meningitis, yellow fever, rabies — we simply know what we’re doing,” he said. “And that’s why we’re excited about our approach in Covid-19. Let’s be frank: we’re using a platform that we use every year, so we know how to do it. We know what to do, and we’re moving at speed.”

As for when Sanofi’s vaccine candidates could be available to the public, should it prove safe and effective, Hudson said: “We’re already in human studies. We’re manufacturing doses pretty much right now, and we’ll be available some point early next year.”
Forgot to mention, Sanofi is the world leader of vaccines. They represent the gold standard, so keep an eye on their trial and vaccine candidate.
 
She said she has asthma.. sitting alone with her kids in an otherwise empty bleacher... just leave her the F alone as soon as you hear ASTHMA.

That arrest was a crime. There should be riots... destroy every fast food place anywhere near that "officer's" house, commute and place of work.
 
You know.. all this comparing of countries and what they did and how it worked for them.. doesn't consider that the immunity rate of different populations with different exposures to past viruses including coronaviruses could have done for them.

That is saying what Sweden did compared to South Korea did compared to Japan compared to Vietnam compared to Brazil compared to Italy compared to USA.. it might be the case that none of that really mattered except for small percentages.. which are real peoples' lives.. but the majority of the differences could very well be some innate immunity numbers.
 
She said she has asthma.. sitting alone with her kids in an otherwise empty bleacher... just leave her the F alone as soon as you hear ASTHMA.

That arrest was a crime. There should be riots... destroy every fast food place anywhere near that "officer's" house, commute and place of work.
she should have complied!!!
 
Good article and excellent video featuring Gov. Murphy and Dr. Fauci talking about New Jersey's very difficult start, being hit harder than anywhere else, mostly unexpectedly, and how NJ got control of the outbreak and then about the ongoing efforts to carefully reopen the economy (which Dr. Fauci lauded). He said NJ is well situated (being "deep green" on their 5-color grading chart, with deep green being the best) to reopen even a bit more (prudently) soon, given very low case rates and positivity percentages - much moreso than many states with far higher case/positivity rates.

They also discussed a wide range of aspects of the coming vaccines and it's good to hear Dr. Fauci being so confident that this will only be a scientific decision on safety and efficacy and politics will play no role. Let's hope his confidence is rewarded. As an aside, Dr. Fauci is hoping for 70-75% vaccine effectiveness and 70+% vaccination rate, but he realizes that the public must have confidence in the data and the process before reaching that level.

They also talked about the reopening of schools and Dr. Fauci thought NJ's plan with mixed virtual/in-school learning in most locations with key metrics for guidance (especially for in-person learning) was a sound way to go. He acknowledged that there will be cases there and in restaurants and in homes and elsewhere, but if we can mimimize them and trace/isolate the ones we see, there's a good chance NJ can prevent flare-ups from becoming outbreaks.

They also had a little banter at the end - I had no idea Fauci was such a big hoops fan. Said he got his grandfather's "fast" genes, but also, unfortunately his "short" genes, so that's why he was the point guard on his HS team.

https://patch.com/.../watch-live-murphy-speaks-dr-fauci...

https://www.facebook.com/watch/live/?v=631905121047750&ref=external
 
Interesting JAMA medical perspective on COVID "long haulers" - people who had COVID who have lingering significant effects months after "recovering." This was seen to some extent with the original SARS, too, but is obviously a much bigger issue given a much bigger pandemic. While deaths and death rates obviously get the most attention, the lingering effects of COVID in many will likely end up being a major secondary story. An excerpt is below.

https://jamanetwork.com/journals/jama/fullarticle/2771111

The longer the pandemic drags on, the more obvious it becomes that for some patients, COVID-19 is like the unwelcome houseguest who won’t pack up and leave. “Anecdotally, there’s no question that there are a considerable number of individuals who have a postviral syndrome that really, in many respects, can incapacitate them for weeks and weeks following so-called recovery and clearing of the virus,” Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases, said in July during a COVID-19 webinar organized by the International AIDS Society.

That appeared to be the case with the first severe acute respiratory syndrome (SARS), which emerged in 2002 and was also caused by a coronavirus. Some people who were hospitalized with SARS still had impaired lung function 2 years after their symptoms began, according to a prospective study of 55 patients in Hong Kong. But only 8096 people were diagnosed with SARS worldwide—a fraction of the COVID-19 cases reported each day in the US alone...

...As with SARS, many COVID-19 long haulers are health care workers who had massive exposure to the virus early in the pandemic, neuroimmunologist Avindra Nath, MD, of the National Institute of Neurological Disorders and Stroke (NINDS), noted in a recent editorial.

Overall, approximately 10% of people who’ve had COVID-19 experience prolonged symptoms, a UK team estimated in a recently published Practice Pointer on postacute COVID-19 management. And yet, the authors wrote, primary care physicians have little evidence to guide their care.
 
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Good article and excellent video featuring Gov. Murphy and Dr. Fauci talking about New Jersey's very difficult start, being hit harder than anywhere else, mostly unexpectedly, and how NJ got control of the outbreak and then about the ongoing efforts to carefully reopen the economy (which Dr. Fauci lauded). He said NJ is well situated (being "deep green" on their 5-color grading chart, with deep green being the best) to reopen even a bit more (prudently) soon, given very low case rates and positivity percentages - much moreso than many states with far higher case/positivity rates.

They also discussed a wide range of aspects of the coming vaccines and it's good to hear Dr. Fauci being so confident that this will only be a scientific decision on safety and efficacy and politics will play no role. Let's hope his confidence is rewarded. As an aside, Dr. Fauci is hoping for 70-75% vaccine effectiveness and 70+% vaccination rate, but he realizes that the public must have confidence in the data and the process before reaching that level.

They also talked about the reopening of schools and Dr. Fauci thought NJ's plan with mixed virtual/in-school learning in most locations with key metrics for guidance (especially for in-person learning) was a sound way to go. He acknowledged that there will be cases there and in restaurants and in homes and elsewhere, but if we can mimimize them and trace/isolate the ones we see, there's a good chance NJ can prevent flare-ups from becoming outbreaks.

They also had a little banter at the end - I had no idea Fauci was such a big hoops fan. Said he got his grandfather's "fast" genes, but also, unfortunately his "short" genes, so that's why he was the point guard on his HS team.

https://patch.com/.../watch-live-murphy-speaks-dr-fauci...

https://www.facebook.com/watch/live/?v=631905121047750&ref=external

A 70% efficient vaccine would be amazing. Looking forward for this virus being a thing of the past next summer.
 
MD-based Novavax announced the start of their phase III vaccine trial in the UK today. This single shot vaccine could be ready by January and many think it's a front-runner for high efficacy because of strong immunity responses in animals and humans in early clinical trials. The vaccine uses proteins doped onto adjuvant nanoparticles (the adjuvant is a saponin-based adjuvant to enhance the immune response by improving transport of the antigens to active areas like lymph nodes), a technology which is about to be approved for an influenza vaccine. Supposedly a US phase III study is starting in October. The think they can have 100MM doses by 1Q21 and 2 billion by the end of 2021.

http://ir.novavax.com/news-releases...hase-3-efficacy-trial-covid-19-vaccine-united

https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html

https://rutgers.forums.rivals.com/threads/ot-daily-covid-thread-9-22.201353/post-4705817
 
she should have complied!!!
why? just to avoid getting tased and arrested?

you guys got brownshirts in the streets and now gestapo rounding up those that are different

congratulations on showing America what you guys are all about
 
why? just to avoid getting tased and arrested?

you guys got brownshirts in the streets and now gestapo rounding up those that are different

congratulations on showing America what you guys are all about
Because we respect our law enforcement!!
 
ONE of the supposed advantages of legalizing MJ is to end the illegal importation and sale of the drug.
Of course, when the state gets so greedy that it taxes legal MJ at a rate the makes the illegal stuff much cheaper, that is not going to happen.
 
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This is on COVID and vaccines and politics, but it needs to be discussed, IMO, so here we go...

So the plot keeps thickening on the political side of the vaccine effort, which is unfortunate. If the politicians would just stfu, we'd all be in much better shape and confidence in getting a vaccine would be growing, instead of plummeting, as per a recent Pew Research poll, which showed that now only 51% of Americans are likely to get a COVID vaccine down from 72% in May. Having said that, IMO, the lion's share of the blame is on Trump for consistently appearing as though he is willing to disregard vaccine safeguards in order to launch a vaccine by the election, via an Emergency Use Authorization. However, the rhetoric on the dem's side on this one has been a bit over-the-top, IMO, too and has added to the confusion/loss of confidence - but the reason I place a lot more blame on Trump is the dems wouldn't be saying a thing, if Trump wasn't poking the bear.

https://www.pewresearch.org/science...divided-over-whether-to-get-covid-19-vaccine/

Anyway, Trump has ratcheted up his rhetoric on this in the past day or so, saying he disagrees with the FDA tightening requirements for an EUA for a vaccine (as they've been discussing) and having Azar invoke the legal provisions of the EUA afforded to him by the law in order to disregard the possible objections of the scientists at the FDA. The link below provides an excellent summary of the situation (from Endpoints, the well-respected biotech blog/newsletter). This is kind of an update on the thread below.

https://endpts.com/azar-falls-in-li...es-reinforcing-a-dark-signal-sent-to-the-fda/

https://rutgers.forums.rivals.com/threads/ot-daily-covid-thread-9-23.201383/post-4706709

And here's where it gets interesting, legally. Dr. Henry Miller wrote a really detailed, insightful article on this last week and he was the first one I saw point out the issues in the USC Code on EUAs, which predate any of this. There exists a loophole in the Federal LAw (U.S. Code, Title 21, Chapter 9, subsection c), that could be used unilaterally by Hahn’s boss, the HHS Secretary, Alex Azar, a political appointee and lawyer (not a scientist). The relevant section of the law, “Authorization for medical products for use in emergencies,” specifies that:
The Secretary may issue an authorization under this section with respect to the emergency use of a product only if, after consultation with the Assistant Secretary for Preparedness and Response, the Director of the National Institutes of Health, and the Director of the Centers for Disease Control and Prevention… the Secretary concludes (1) that an agent referred to in a declaration under subsection (b) can cause a serious or life-threatening disease or condition; (2) that, based on the totality of scientific evidence available to the Secretary, including data from adequate and well-controlled clinical trials, if available, it is reasonable to believe that (A) the product may be effective in diagnosing, treating, or preventing (i) such disease or condition.”
The article notes that the Secretary is "only required to consult with, but not obtain agreement from, the three subordinates specified in the law." In a normally functioning government, there should be no way possible for the Secretary of HHS, who is not a scientist, to overrule the heads of NIH and CDC (it's also odd that the head of the FDA is not part of that advice group), if their scientific advice is that an EUA is not safe to pursue and all of these folks are on record saying that politics will play no role in any EUA for any vaccine, but I certainly share the concern that there is a path to ignore such advice.

https://geneticliteracyproject.org/...ctober-surprise-could-be-an-october-disaster/

This is a time when Americans and our scientists and politicians should all be on the same page, as we're on the precipice of an historic breakthrough in vaccine technology, assuming one or more of these vaccines is safe and effective (which most expect), as nobody thought this could be done in under a year, let alone in under 24 months when this all started - and assuming we achieve this, this will likely be Trump's biggest accomplishment of his presidency, as he was a huge driving force behind Warp Speed. We should be celebrating this likely accomplishment, not arguing over how it might be deployed prematurely.
 
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