Well, discussions of masks, deaths, and virus origins always lead to churn in these threads, so let's try to get back to some less controversial COVID science. Today, Derek Lowe posted an interesting article speculating about what might happen if people decided to get two different vaccines, which I assume can happen. He discussed how this has happened for past vaccines for things like polio, Hepatitis-A and B, and meningococcus, where the two vaccines taken were usually very similar to each other and in most cases, there were no issues.
However, he noted that for COVID we're going to likely soon have 2 mRNA vaccines (Moderna/Pfizer), 2 adenovirus vector vaccines (J&J/Astra-Zeneca) and a protein-based vaccine (Novavax), so mixing types of vaccines, while probably not an issue, is certainly something we have no data on and won't for some times. Perhaps the people who do this will be kind enough to register that they've done it, so data can be gathered.
https://blogs.sciencemag.org/pipeline/archives/2020/12/02/taking-two-different-vaccines
He didn't get into this too much, but folks in the comments section did and it's been discussed here also, and that's the topic of whether previous infection/recovery (with likely immunity) will be an issue. The UK CDC equivalent has said that there shouldn't be an issue with previously infected people getting the vaccine. In a perfect world, I think we'd do an immunology screen of people who say they've recovered and if they show good levels of antibodies (and T-cells, since we seem to be getting those tests ready for prime time), then perhaps we'd ask them to hold off and let someone who hasn't been exposed get the vaccine.
Problem is I don't think we're going to have that kind of testing infrastructure, so it's quite likely that quite a few vaccines will be "wasted" on people who are very, very likely to already be immune, since the CDC now estimates that close to 30% of the population have likely been infected (many of those asymptomatic who should still be immune). Interesting questions...
https://www.npr.org/sections/corona...vid-19-cases-could-be-approaching-100-million