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OT: COVID Science - Pfizer/Moderna vaccines >90% effective; Regeneron antibody cocktail looks very promising in phase II/III trial and more

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Hopefully CA is doing genetic analysis on the strain circulating around LA county. That rate of growth with the restrictions that were previously in place along with new restrictions does not add up and suggests a more infectious variant in circulation. There are more infectious strains that have been circulating in Europe since the end of the summer, was inevitable they would make their way over here.
 
I don't know why that's surprising. It's not like we're dumping vaccine rain on the entire population. Masks will continue as long as they're needed.

What's the big deal, anyway? Do you refuse to cover your mouth when you sneeze, too? Breathe in sawdust liberally when cutting wood? Get wind rash all over your face because you burned your scarf?
 
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What policy in NJ? You can eat indoors here. The curfew I think is silly, but otherwise other than capacity limits and wearing a mask it's pretty normal.

Limitations on travel and big gatherings are pretty much everywhere at least in the case of sports a B1G rule.
No indoor sports but gyms open for one. But we aren’t just talking NJ here
 
Weren't you complaining about gyms not being open before they reopened?

You guys go through life being spoiled, whiny children or is that something special you save for the board?
I didn’t complain about any one specific entity or another. I complain about policy that has no scientific basis. I complain government deciding what businesses can be open on a whim. Never ever taking into account how these decisions ruin peoples lives. With zero science behind the decisions.
 
I didn’t complain about any one specific entity or another. I complain about policy that has no scientific basis. I complain government deciding what businesses can be open on a whim. Never ever taking into account how these decisions ruin peoples lives. With zero science behind the decisions.

So people's lives are ruined because they can't play or watch indoor sports for a month? Explain.
 
So people's lives are ruined because they can't play or watch indoor sports for a month? Explain.
It’s not about kids playing or parents watching. That’s a typical simpleton take from you. How about the trainers and coaches who make a good chunk of their money working and training in these facilities? How about the people who own these facilities? And it’s not “a month”. These same places were shut down in March, April, May and June. They couldn’t go to fields or parks because they were closed most of the Spring as well. But it’s not your problem so you don’t give it a second thought. And again, it’s based on ZERO science.
 
I don't know why that's surprising. It's not like we're dumping vaccine rain on the entire population. Masks will continue as long as they're needed.

What's the big deal, anyway? Do you refuse to cover your mouth when you sneeze, too? Breathe in sawdust liberally when cutting wood? Get wind rash all over your face because you burned your scarf?
Sometimes I paint walls without a respirator and keep the windows closed just to make a point
 
gyms being open in NJ for 4 months without any major spikes tied to any specific gym pretty much proves that Murphy was at least 2 months too late in opening them in the first place if not more
 
It’s not about kids playing or parents watching. That’s a typical simpleton take from you. How about the trainers and coaches who make a good chunk of their money working and training in these facilities? How about the people who own these facilities? And it’s not “a month”. These same places were shut down in March, April, May and June. They couldn’t go to fields or parks because they were closed most of the Spring as well. But it’s not your problem so you don’t give it a second thought. And again, it’s based on ZERO science.

Yeah, my simpleton take ... Worrying more about not watching our medical system taken over by a once-a-century pandemic than I am about Gym Teacher Joe not getting his extra stipend for coaching wrestling or some trainer making stupid money turning kids sports into the mini-pros having to scale back for a while. What screwed up priorities!

You care so much, I sure hope you've been hiring those trainers for private sessions.
 
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Yeah, my simpleton take ... Worrying more about not watching our medical system taken over by a once-a-century pandemic than I am about Gym Teacher Joe not getting his extra stipend for coaching wrestling or some trainer making stupid money turning kids sports into the mini-pros having to scale back for a while. What screwed up priorities!

You care so much, I sure hope you've been hiring those trainers for private sessions.
Would love to but can’t. You know because fields were closed and now facilities are. But yea, I prepaid my one daughters coach for 20 sessions so he could pay his rent.
next time the hospital system gets overloaded will be the first. How we don’t run out of ventilators this tome around again.
 
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It’s the same Story almost every flu season. Too bad California didn’t take this seriously with lockdowns and mask mandates.
 
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Vaccine #2 just about approved!


A second coronavirus vaccine is one step closer to being delivered, after a federal panel of outside experts on Thursday endorsed a coronavirus vaccine from Moderna and recommended the Food and Drug Administration (FDA) move forward with emergency authorization.

The panel voted 20-0, with one abstention, that the safety and efficacy of the vaccine outweigh the risks for use in individuals age 18 and older.

Based on the track taken by the already-approved vaccine manufactured by Pfizer and BioNTech, the FDA could grant emergency use authorization for the Moderna vaccine as soon as Friday.
 
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Would love to but can’t. You know because fields were closed and now facilities are. But yea, I prepaid my one daughters coach for 20 sessions so he could pay his rent.
next time the hospital system gets overloaded will be the first. How we don’t run out of ventilators this tome around again.

Next time being the first is kinda the whole idea.

Glad we agree that these measures are working!
 
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Warp speed is a raging success. Guess it's safe for the talking heads to praise the plan now. They panned it in May and said that having a vaccine by the end of the year was unlikely.

Gen. Perna grew up in Morris Hills.

Who panned it in May? Nobody I know of. It's the one thing in this whole mess that the Administration did extremely well on, as I've said from the day it was announced.
 
Vaccine #2 just about approved!


A second coronavirus vaccine is one step closer to being delivered, after a federal panel of outside experts on Thursday endorsed a coronavirus vaccine from Moderna and recommended the Food and Drug Administration (FDA) move forward with emergency authorization.

The panel voted 20-0, with one abstention, that the safety and efficacy of the vaccine outweigh the risks for use in individuals age 18 and older.

Based on the track taken by the already-approved vaccine manufactured by Pfizer and BioNTech, the FDA could grant emergency use authorization for the Moderna vaccine as soon as Friday.
Yep and it looks just as good as the Pfizer one, plus it doesn't have the cryogenic storage needs. Should be approved for emergency useFriday or Saturday. Been away for a few days given the snowstorm, but if it wasn't discussed, there was one other very interesting observation from the Moderna trial. They looked at asymptomatic infections in the nose after the first shot and saw reductions vs. placebo, but the results are merely suggestive of a reduction in asymptomatic infections for vaccinated people and not conclusive (not enough statistical power); Pfizer did not explore this, but given how similar results have been for both vaccines, one would expect them to share this element of performance.

But common sense says that a primed immune system ought to be able to prevent infections completely in more people than those who aren't vaccinated but get infected. Not having ironclad data on that, though is why many think we'll still need distancing/masking for some time, unless we can develop that data by monitoring enoug people post-vaccination after approval. However, IMO, we're going to see case rates start to plummet by the end of January, after vaccinating ~20MM health care workers, 2-3MM LTC residents and a good chunk (tens of millions) of front line workers and the elderly in general (plus we'll likely be near 30-35% of the general population having been infected and no longer infectious). If we see cases plummet by February, perhaps restrictions will be loosened for some events like sports, especially if one can show a record of vaccination. I hope so, as I really want to go to the NCAAs this year, given what happened last year.

The other good news we got the other day was that the Administration announced that they had purchased another 100MM doses from Moderna (for 50MM people) for 2Q21, to augment the 100MM doses from Moderna through 1Q21 and the 100MM doses from Pfizer through 1Q21. This means we'll have enough doses for 100MM people (30% of the US, although it's actually 37% of vaccine-eligible people, since ~65MM children aren't eligible for the vaccine yet). The extra 100MM doses get us to enough for 55% of adults in 2Q, which is likely to get us to herd immunity when combined with the number of people who have already been infected and are immune (there's some overlap, as some of them will get vaccinated). And if a few of the next wave of vaccines can come through by 2Q, we'll be in even better shape. That's why I think we're going to get back to at least close to normal sometime in 2Q21, faster than most others think.

https://www.cidrap.umn.edu/news-per...nalysis-details-support-moderna-covid-vaccine

https://www.nytimes.com/2020/12/15/...tion=click&module=RelatedLinks&pgtype=Article

P.S. What a mess this thread has become with all the incessant bickering about mostly non-scientific crap, which was not the aim of the thread, but moderation has been abdicated from what I can tell. When T is my favorite poster in a thread, something has gone wrong, lol. 😄😄
 
With all he mask discussion earlier... I have a First Hand Mask wearing COVID transmission account between two mask wearing people : My wife contracted Covid a couple months ago. She is a health care worker where they require surgical masks 100% of the time (with more protection if dealing with known or suspected COVID). She and a colleague were both wearing surgical masks at a table in the same room together for 15-20 minutes. The day after they met the colleague developed symptoms and later tested positive for COVID. My wife developed symptoms about 4 days later and also tested positive. There is obviously no proof that her encounter with her colleague was her source of the virus, but she had not been near any other known positive COVID persons in the prior 14 days that she knew about, so the circumstantial evidence is pretty strong that her transmission originated from that person while they both were wearing good quality surgical masks. Masks can certainly limit transmission but as we all know, mask wearing, especially if it is not N95 quality or better, is not going to stop all transmissions. And my wife was fortunate to have a mild case, 1 to 2 days of flu like symptoms, then back to normal in about 4-5 days from onset... and I never caught it, or had no symptoms if I did.
 
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Yep and it looks just as good as the Pfizer one, plus it doesn't have the cryogenic storage needs. Should be approved for emergency useFriday or Saturday. Been away for a few days given the snowstorm, but if it wasn't discussed, there was one other very interesting observation from the Moderna trial. They looked at asymptomatic infections in the nose after the first shot and saw reductions vs. placebo, but the results are merely suggestive of a reduction in asymptomatic infections for vaccinated people and not conclusive (not enough statistical power); Pfizer did not explore this, but given how similar results have been for both vaccines, one would expect them to share this element of performance.

But common sense says that a primed immune system ought to be able to prevent infections completely in more people than those who aren't vaccinated but get infected. Not having ironclad data on that, though is why many think we'll still need distancing/masking for some time, unless we can develop that data by monitoring enoug people post-vaccination after approval. However, IMO, we're going to see case rates start to plummet by the end of January, after vaccinating ~20MM health care workers, 2-3MM LTC residents and a good chunk (tens of millions) of front line workers and the elderly in general (plus we'll likely be near 30-35% of the general population having been infected and no longer infectious). If we see cases plummet by February, perhaps restrictions will be loosened for some events like sports, especially if one can show a record of vaccination. I hope so, as I really want to go to the NCAAs this year, given what happened last year.

The other good news we got the other day was that the Administration announced that they had purchased another 100MM doses from Moderna (for 50MM people) for 2Q21, to augment the 100MM doses from Moderna through 1Q21 and the 100MM doses from Pfizer through 1Q21. This means we'll have enough doses for 100MM people (30% of the US, although it's actually 37% of vaccine-eligible people, since ~65MM children aren't eligible for the vaccine yet). The extra 100MM doses get us to enough for 55% of adults in 2Q, which is likely to get us to herd immunity when combined with the number of people who have already been infected and are immune (there's some overlap, as some of them will get vaccinated). And if a few of the next wave of vaccines can come through by 2Q, we'll be in even better shape. That's why I think we're going to get back to at least close to normal sometime in 2Q21, faster than most others think.

https://www.cidrap.umn.edu/news-per...nalysis-details-support-moderna-covid-vaccine

https://www.nytimes.com/2020/12/15/...tion=click&module=RelatedLinks&pgtype=Article

P.S. What a mess this thread has become with all the incessant bickering about mostly non-scientific crap, which was not the aim of the thread, but moderation has been abdicated from what I can tell. When T is my favorite poster in a thread, something has gone wrong, lol. 😄😄
Another 100 million Pfizer doses should be announced soon, most coming in Q2 (after gov negotiations). That will be 400 million total doses by the end of June'ish.....not including J&J if positive or AZ if they figure out their data.
 
Another 100 million Pfizer doses should be announced soon, most coming in Q2 (after gov negotiations). That will be 400 million total doses by the end of June'ish.....not including J&J if positive or AZ if they figure out their data.

Yes, negotiations on that are ongoing and would bring the total from Pfizer and Moderna to 400MM total doses for 200MM total people by the end of 2Q21 (if not sooner), which is enough for 74% of eligible adults (children are not approved to get the vaccine, at least not yet) - and as per below, maybe we can even get close to 90% given the "extra" vaccines per vial.

https://www.nytimes.com/live/2020/12/15/world/covid-19-coronavirus

The other interesting tidbit is that they're "finding" 1-2 "extra" doses in most Pfizer vaccine vials, which are filled to provide at least 5 doses - they overfill slightly to ensure that and a little bit of overfill goes a long way when a single dose is 0.3 milliliters or 300 microliters (a drop of water is about 50 microliters). That could mean 20-40% more doses per vial, which is very good news.

https://www.nbcnews.com/health/heal...-hold-some-extra-doses-experts-say-s-n1251548
 
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Another 100 million Pfizer doses should be announced soon, most coming in Q2 (after gov negotiations). That will be 400 million total doses by the end of June'ish.....not including J&J if positive or AZ if they figure out their data.

Read that too. Sounds like the US isgoing to help beef up manufacturing and as a result we get 100mil more doses in Q2.
 
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Disgusting fear mongering by the media. They should be fined for reporting this. Yet the sheep believe.


the stories of people dying from Covid are hearbreaking...but guess what there are way more people dying of other stuff and their stories are heartbreaking as well and they make up the majority in the hospital and of people dying. The nursing homes continue to be the top place where covid deaths are found but yet receives the tiniest of attention from the MSM. Yes Covid is real and people should take precautions, not its not deserving of constant everyday fearmongering and daily death count monitoring and to be used for political purposes. Murphy's comments the other day about young people you will kill your parents and grandparent is disgraceful at best. The lockdowns in California look asburd given their meteoric rise in cases since
 
Don't know if this has been discussed here. But if not, I'd appreciate comments from some of the knowledgeable people on this forum.

The doctor's argument seems compelling, but ...

 
the stories of people dying from Covid are hearbreaking...but guess what there are way more people dying of other stuff and their stories are heartbreaking as well and they make up the majority in the hospital and of people dying. The nursing homes continue to be the top place where covid deaths are found but yet receives the tiniest of attention from the MSM. Yes Covid is real and people should take precautions, not its not deserving of constant everyday fearmongering and daily death count monitoring and to be used for political purposes. Murphy's comments the other day about young people you will kill your parents and grandparent is disgraceful at best. The lockdowns in California look asburd given their meteoric rise in cases since

Do the lock downs look absurd ...because what does that meteoric rise look like if there are no lock downs?

That's the problem with your whole argument.
 
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No indoor sports but gyms open for one. But we aren’t just talking NJ here

The only people I see complaining live in NJ. As a federalist system, we don't have the right to tell other states how to handle their affairs.

Seems like indoor sports would not allow for social distancing while the gym could close every other machine.
 
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The guy who cries about Hs kids that can’t play sports only because it affects his business. There always a reason, financially, they cry.

Now they're also crying about other states where they don't go or in some cases have never even been.

It's a desperately needed catharsis with all the other losing going on for them especially given last Friday and Monday.
 
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The guy who cries about Hs kids that can’t play sports only because it affects his business. There always a reason, financially, they cry.
HS sports, well any sports for that matter have no bearing on my businesses from a financial standpoint. #outofmeat
 
Fear mongering is Dave’s thing. Remember when we were all gonna die because we’d run out of meat?


the post was NewWAVE DAVE not me. I was wondering what you were talking about.
 
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Do the lock downs look absurd ...because what does that meteoric rise look like if there are no lock downs?

That's the problem with your whole argument.

Any science to back that up...Florida and the Dakotas and midwest wave hello as their case rates are under under control
 
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