More or less what I was about to say.
The RU defensive coaches might be agonizing over the tradeoff. Either send more people to create pressure, leaving our DBs on islands w/their receivers. Or else rely on our DL to create enough pressure and get creative trying to get the OSU QB to throw some potential INTs into unexpected coverage.
If I thought we could match up decently with OSU, I'd argue that a more conservative approach that forces the OSU to make more throws would be better. And I do think that approach would keep the game closer.
But I don't think we match up well at all. So I think it's likely we'll see some unusually risky gambles from the DC aimed at getting pressure on the OSU QB. If those gambles don't work, we'll see them getting some big numbers in the passing game and the game won't wind up close.
Personally, I don't care about losing close versus losing big. I'd rather see us go all out to win by taking some chances that wouldn't make any sense against opponents we have a more realistic chance at beating. Only way to win, IMO. Especially if they stop our run game, which is not unlikely.