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OT: a good friend is STUCK IN CHINA

My neighbor works for a finance company in NYC. Starting Monday the company has closed their offices are is requiring all employees to work remotely for 3 weeks straight. This is the first i'm hearing of these type of actions... anyone else have similar stories?

Any media reports on this?
I want to send to my manager.

1.5hr commute each way into lower manhattan sucks.
 
Any media reports on this?
I want to send to my manager.

1.5hr commute each way into lower manhattan sucks.
I had someone tell me some companies are doing a 50-50 some employees in for two weeks straight others from home and then they switch.
 
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It’s basically about a handful of people in China who tested positive for the virus a second time after having recovered and been negative. Also one in Japan I posted about a few posts later.

You might look at this like when a man gets an initial genital herpes infection. He usually will be flagrantly symptomatic and eventually recover and you can't recover the virus anymore because the lesions are gone.
However the virus really can become latent and go into hiding based upon various immune factors. It may reemerge a month later, several months later or never. It will then reactivate with less flagrant lesions, be shedding virus again and the man can spread it on to various other partners. In the case of herpes it's a fairly innocuous virus for the man but not so for the woman and any potential pregnancy. luckily there's been no documented transmission vertically in the fetus with women infected with coronavirus.
I think this is going to be more important for our morbid elderly patients who are at risk. But you may get a false sense of a security in that you are cured after the illnesses over and over the quarantine because the virus may re-emerge in a carrier state like in herpes.
SARs causes little to no cold-like symptoms because it attaches to bronchoepithelial cells and it's receptor is totally different than MERS.
And the attraction for these receptors which we refer to as tropism somehow morphed from crazy other animal species. So it's a lot easier to study rat in a lab than camels but how do you get a rat to acquire a camel or bat or a human receptor to study such a virus. Well you actually can by infecting it with another virus which can transform some of these receptors to make them susceptible to the binding site of the particular coronavirus. There are so many moving parts which is why things don't happen overnight as opposed to any dragging of the feet.
 
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You might look at this like when a man gets an initial genital herpes infection. He usually will be flagrantly symptomatic and eventually recover and you can't recover the virus anymore because the lesions are gone.
However the virus really can become latent and go into hiding based upon various immune factors. It may reemerge a month later, several months later or never. It will then reactivate with less flagrant lesions, be shedding virus again and the man can spread it on to various other partners. In the case of herpes it's a fairly innocuous virus for the man but not so for the woman and any potential pregnancy. luckily there's been no documented transmission vertically in the fetus with women infected with coronavirus.
I think this is going to be more important for our morbid elderly patients who are at risk. But you may get a false sense of a security in that you are cured after the illnesses over and over the quarantine because the virus may re-emerge in a carrier state like in herpes.
SARs causes little to no cold-like symptoms because it attaches to bronchoepithelial cells and it's receptor is totally different than MERS.
And the attraction for these receptors which we refer to as tropism somehow morphed from crazy other animal species. So it's a lot easier to study rat in a lab than camels but how do you get a rat to acquire a camel or bat or a human receptor to study such a virus. Well you actually can by infecting it with another virus which can transform some of these receptors to make them susceptible to the binding site of the particular coronavirus. There are so many moving parts which is why things don't happen overnight as opposed to any dragging of the feet.
I hope they're doing some follow up studies on patients who have "recovered" to see if these are isolated cases or something more ubiquitous.
 
I had someone tell me some companies are doing a 50-50 some employees in for two weeks straight others from home and then they switch.

:Pray: :Praying::Pray: :Praying:

I work for a major multi-national financial services company.
I believe the China offices have been closed for a while now.

We are actually having a medical awareness webinar today with some doctor about the general situation and provide actual information about COVID-19 instead of getting it from news reports.

I'm sure someone will ask about closing US offices.
 
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Guys my buddy Randy “Honkus” Stockstill AND his family (including their 6-month old son) are currently stuck in Wuhan, China.

There is a state department plane headed there to bring US Citizens back BUT they could use ANY AND ALL help (if possible) to get on the plane!! Please follow this link for additional info as to whom to tweet at or contact AND IF you have direct White House contacts PLEASE follow up with them if you can!!

https://www.tigerdroppings.com/rant...-honkus-stuck-just-outside-of-wuhan/88243553/

Thanks!

NUTS
How are your friends doing health wise?
 
Any media reports on this?
I want to send to my manager.

1.5hr commute each way into lower manhattan sucks.

Nothing in the media that i've seen, but i'm having dinner with the neighbor tonight so will get more detail from him.

I've got a flight to Denver Monday morning from EWR.... my wife is freaking out that i'm going to be in Newark Airport
 
First cases in Africa and Mexico reported.

if this gets to India all hell will break out.
Africa has a few cases but Northern Africa this is in Nigeria so farther south. Mexico has two cases. All three cases came from abroad from Italy.

I tend to think some cases originating in Italy will pop up here sooner or later in this area.
 
I hope they're doing some follow up studies on patients who have "recovered" to see if these are isolated cases or something more ubiquitous.
I've been wrestling with this whole "reinfection" idea. Unless the virus is doing something really screwy to peoples immune systems (and it might be, at least in some cases), it just doesn't seem likely that people are getting reinfected a couple of weeks after the first infection. That's just not how most viruses work.

I think it's more likely that these cases are reflective of testing issues. The PCR tests seem to be somewhat "flaky" for lack of a better term. There have been numerous cases reported from China where people were obviously symptomatic (fever, cough) and even with ct manifestation of pneumonia, who repeatedly tested negative before finally getting a positive result. So I bet most of these "reinfection" cases are due to the nature of testing - the people still have virus in their systems but the tests come back negative. Then later they get a positive test - not because they were reinfected but because they never got rid of all the virus.

Another possibility is that there is residual viral RNA in the system and the tests sometimes pick it up, and sometimes don't. These people may or may not still be contagious and that needs to be figured out obviously. From what I've read there are other viral infections where people can still test positive for a long time but are not actually infected or shedding virus.

If it turns out that true reinfection is common then we are in big trouble. I'd rather not contemplate that scenario.
 
I'm sure it's there just as I'm sure it's here (and not just the one case in California). More testing will start to reveal more cases. Unless the CDC is prevented from sharing that information, of course.
I was just looking at flu cases in India over the years and it’s grown from the single digit thousands to mid twenty thousands over the years. That’s not even close to what we have here and their population is much bigger.

I think India is humid for quite a bit of the year depending on which part of the country so might slow the spread of these coronaviruses... at least not to the extent you’d see in other countries just judging by their flu numbers.
 
I've been wrestling with this whole "reinfection" idea. Unless the virus is doing something really screwy to peoples immune systems (and it might be, at least in some cases), it just doesn't seem likely that people are getting reinfected a couple of weeks after the first infection. That's just not how most viruses work.

I think it's more likely that these cases are reflective of testing issues. The PCR tests seem to be somewhat "flaky" for lack of a better term. There have been numerous cases reported from China where people were obviously symptomatic (fever, cough) and even with ct manifestation of pneumonia, who repeatedly tested negative before finally getting a positive result. So I bet most of these "reinfection" cases are due to the nature of testing - the people still have virus in their systems but the tests come back negative. Then later they get a positive test - not because they were reinfected but because they never got rid of all the virus.

Another possibility is that there is residual viral RNA in the system and the tests sometimes pick it up, and sometimes don't. These people may or may not still be contagious and that needs to be figured out obviously. From what I've read there are other viral infections where people can still test positive for a long time but are not actually infected or shedding virus.

If it turns out that true reinfection is common then we are in big trouble. I'd rather not contemplate that scenario.
i tend to think it’s something to do with the testing too but what do I know I’m not a scientist.
 
LOL...I was just listening to the daily WHO briefing and one of the panel members (not Tedros, the other guy) said the following:

"If this was influenza we would probably have call it (pandemic) by now"

I'm not even going to try to describe his convoluted explanation. Just shaking my head.
 
If hundreds of people are walking around the US asymptomatically with this virus or a million people in China have it asymptomatically then the fatality rate is not much worse than the common flu. It’s only scary if the numbers of confirmed infections are relatively accurate. It can’t be both highly deadly and within the US currently extremely widespread.
 
If hundreds of people are walking around the US asymptomatically with this virus or a million people in China have it asymptomatically then the fatality rate is not much worse than the common flu. It’s only scary if the numbers of confirmed infections are relatively accurate. It can’t be both highly deadly and within the US currently extremely widespread.
I mean....maybe. And maybe not. Remember that it is a long course disease and cases often aren't resolved for 2-4 weeks. So you could be seeing people walking around right now who don't appear that ill, but who later go downhill rapidly. And no one really know how many cases are asymptomatic or minor.

That doctor in China who was the early whistleblower, didn't die for something like 3 weeks after being diagnosed.

Cases that are just being discovered now in places like South Korea won't be resolved for several weeks. We'll just have to wait and see.
 
I mean....maybe. And maybe not. Remember that it is a long course disease and cases often aren't resolved for 2-4 weeks. So you could be seeing people walking around right now who don't appear that ill, but who later go downhill rapidly. And no one really know how many cases are asymptomatic or minor.

That doctor in China who was the early whistleblower, didn't die for something like 3 weeks after being diagnosed.

Cases that are just being discovered now in places like South Korea won't be resolved for several weeks. We'll just have to wait and see.

Maybe, we’ll see.

Interesting that Southeast/South Asia hasn’t seen an explosion of cases considering the huge numbers of Chinese there. Maybe they are hiding it but the health system should be overloaded by now considering how early it arrived in that region. All the outbreaks have occurred in more temperate climates.
 
2nd case in California of unknown origin in Santa Clara County.

From WaPo:

California has a second case of community transmission of the coronavirus, a 65-year-old resident of Santa Clara County who has no known history of travel to countries hit hard by the outbreak, people familiar with the case said Friday.

There is also no apparent connection between the new patient and anyone else with the disease caused by the virus, covid-19. On Wednesday, health authorities revealed the nation’s first case of community transmission, a woman in Solano County, California, about 90 miles away.

That means the virus appears to be spreading among at least two separate populations, according to people who spoke on condition of anonymity because the information has not been released publicly.

“I think there’s a strong possibility that there’s local transmission going in California. In other words, the virus is spreading within California, and I think there’s a possibility other states are in the same boat. They just haven’t recognized that yet,” she said.

https://www.nbcbayarea.com/news/coronavirus/another-coronavirus-case-confirmed-in-bay-area/2244511/

https://www.washingtonpost.com/heal...53c93a-5a77-11ea-9b35-def5a027d470_story.html
 
My wife is a doctor and runs the critical care unit of a hospital in NJ. They have established protocols in place, including appropriate PPE when dealing with a suspected patient under investigation.

Her worry is when community spread initially starts occurring in NJ. Not enough testing kits and the usual questions about traveling to
China or bring in contact with a sick person who was in China wont prevent sick people from walking out of the hospital with a common flu diagnosis.

She’s worried about when China loosens travel restrictions, resulting in carriers coming into Newark Airport and JFK.

She puts the likelihood of 1,000 cases in the Tri-state area at 99% this spring.

The USA HAS imposed the travel restriction into the US from Chin--na, not the other way around.

What Chin-na did do, after approx. 5,000,000 million of citizens of Wuhon left the city was restrict travel within a province of approx. 56.000,000. Which was at the same time President Trump was being called racist by his critics in the Congress and news media.
 
Any media reports on this?
I want to send to my manager.

1.5hr commute each way into lower manhattan sucks.

i got a similar email from my work yesterday.
we were told to limit business travel. stay home if you don't feel well. report if you or your household member had traveled overseas in the last 30 days.
then today my boss told me to figure out a way run my project via skype. i am cancelling a business trip that is 2 weeks away.
i was also told if my kid's school experiences a closure to work from home.

i heard similar stories from friends of mine. looks like the CDC/DHS communication was activated. there will be pretty big impact economically for sure.
 
"In the interest of privacy......". BS. They dont want to admit that healthy people are getting this virus, and dying from it. They never hesitate to mention when someone over 70 dies. If this was like the flu, there would not be soldiers keeping people in their towns in northern Italy.
 
I mean....maybe. And maybe not. Remember that it is a long course disease and cases often aren't resolved for 2-4 weeks. So you could be seeing people walking around right now who don't appear that ill, but who later go downhill rapidly. And no one really know how many cases are asymptomatic or minor.

That doctor in China who was the early whistleblower, didn't die for something like 3 weeks after being diagnosed.

Cases that are just being discovered now in places like South Korea won't be resolved for several weeks. We'll just have to wait and see.
Not really, the median time from infection on onset of symptoms is 4 days - yes there are folks who may take 14 days to present with symptoms, but half will show symptoms in 4 days and the vast majority (likely >95%) will show symptoms in 7-8 days. If there were thousands or even hundreds infected, right now, in the US, we'd know about it. Doesn't mean it won't happen, but it just hasn't happened yet.
 
Wear a mask
Surgical masks, alone, offer minimal protection against viruses. They're largely used by surgeons to prevent the surgeon from contaminating the operating area with any viruses or bacteria they may be harboring - and they're used in some countries, especially in Asia, when a person has the flu and doesn't want to spread it to others, as a common courtesy. By far the best thing anyone can do is frequent hand washing (alcohol or soapy water) and being careful not to touch one's face/nose/mouth/eyes after touching surfaces that could be infected - and because that's not always effective, quarantining becomes necessary once infections spread beyond a few people. We'll likely be seeing that soon in the US, at least in some locations.

https://www.livescience.com/face-mask-new-coronavirus.html
 
If there were thousands or even hundreds infected, right now, in the US, we'd know about it. Doesn't mean it won't happen, but it just hasn't happened yet.

How exactly would we know about it when only 500 tests have been done in the whole country and almost all of those have been people with a travel history to China? On social media there are doctors and nurses from hospitals in many parts of the country talking about cases that seem like coronavirus, but that haven't been tested because of the lack of tests and stringent testing regulations. That case in UC Davis sat in a hospital on a ventilator for almost a week before the CDC even agreed to allow a test. We have no idea how many of those kinds of cases are out there. I suspect as testing is ramped up we're going to find the virus is already pretty widespread in the US.

Remember what happened in northern Italy. No one thought there was a problem and then 4 days later there were quarantine zones with armed guards and panic.
 
High school student in Seattle is a fourth case of community spread.

From the article:

Officials say the Snohomish County case involves a Jackson High School student who is currently in home isolation. The student has no recent travel history and the CDC labeled the case as a “possible instance of community spread,” meaning the source of the infection is unknown.

https://q13fox.com/2020/02/28/2-new...ish-co-high-school-student-and-king-co-woman/
 
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I’m just going to throw this out that making a big deal over every individual case of this virus is not helping. It’s a virus. Every year new viruses develop. Yes it need to be addressed by the country is freaking out as if this is the next Black Plague... every couple of years this happens. Whether is bird flu, sars, swine flu, measles, E. coli, etc every year almost it’s something.

respectfully is anyone really that surprised that the only state so far freaking out about this is California? Go figure....
 
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