[roll][roll][roll]Mods can you move this to the CE board.......oh wait....never mind
[roll][roll][roll]Mods can you move this to the CE board.......oh wait....never mind
Agree- why is it ok for 10,000 folks to protest but not 10,000 folks to attend a baseball or football game?how phony was a bunch of health officials saying that people congregating for protests was not a threat of spreading coronavirus but people congregating for other reasons was, did they actually do that...that is why people are skeptical of anything that health officials and scientists and politicians tell us, when they try putting out a statement like that, it just makes your brain fry seeing this kind of pretezel logic. And this isnt a political post, its an observation
Agree- why is it ok for 10,000 folks to protest but not 10,000 folks to attend a baseball or football game?
This from a guy who started his own CoVid thread on the football board because his political motivations could not be questioned there.ROFLMAO!! Too rich coming from the guy with 112,000 nonsensical posts. Just noticed they closed down the CE board - that's why you're whining to Richie like a little girl about Premium I guess. But look on the bright side - you'll be so much more productive at work.
Bingo!from the now-deleted thread...
This from a guy who started his own CoVid thread on the football board because his political motivations could not be questioned there.
The CE board is gone because of liberal whining and you talk about whining.
You haven't given this up yet? I think we all know your stance by now.Masks are like a condom with holes in them. Not all of it gets out but she still is getting pregnant.
The issue with Boulware's study is the subgroups Day1 thru 4 are underpowered to determine interactions between HCQ on Days 1-4. Especially Day 1After Exposure with only 77 evals. I did a hypothetical evaluation where I added 46 obs to Day 1 HCQ with 3 positives to have 8/123 instead of 5/77 same IR 6.5. The interaction analysis is significant to 95%. Which means their is a significant effect between when treatment started. If the subgroups were sufficiently powered it might have actually proved early HCQ worked as post-exposure prophylactic.For anyone interested:
I ran an analysis on Boulware's study and compared DAY 1/DAY 2 HCQ vs PLACEBO DAY 1/2 and here is what I got.
HCQ 17/177 (9.6%)
Placebo 26/169 (15.4%)
Difference between means -5.8% (95% CL -12.8, 0.01)
Odds Ratio = 0.62
p-value = 0.1039 which is 90% significance level.
I also ran Day 1 HCQ versus all placebo since it does not matter what day you got placebo.
HCQ 5/77 (6.5%)
Placebo 58/407 (14.3%)
Difference between means -7.8% (95% CL -16, 0.0)
Odds ratio 0.45
p-value 0.0629 which is 94% significance level.
By the way I also performed a regression analysis on the HCQ data versus Days After Exposure. R2 0f 0.84 and an intercept of about 5% meaning if they took HCQ the day they were exposed you might potentially see a 60% reduction in cases. If you took it before exposure .... seems to align nicely with the data from India. In fact, I would love the Day HCQ data showing infected criteria, etc.
Just a FYI, we have not had a single Covid admission this week at our hospital, a first. We have gone from having 50 Covid pts on our daily census to one. He had a cardiac arrest yesterday but we brought him back to earth and is doing fine now.
Thanks to our Governor (this is NOT political) for shutting down the state and saving thousands of lives, even at GREAT economic pain. This had to done in the Northeast since we have the much more dangerous mutated Covid strain coming over from Europe as opposed to the West coast which has a milder strain. But as you can see, social distancing , hand sanitizer and wearing masks work! Please do not get complacent, this will have to be the new normal until a vaccine comes out or if something unexpected happens, like a mutation again. If you get Corona, you have a much better chance at survival because at least we know what does not work. Trials are ongoing as to what might work and are being fast-tracked. Hundreds of companies are racing against one another to get that vaccine, like nothing in history, so hopefully this will expedite getting an effective vaccine. Only listen to the FDA for this, not the politicians.
It is time to re-open the economy in phases with restrictions. If someone is not wearing a mask, politely ask them to put one on or turn around and leave. Carry hand sanitizer at all times. Most of this stuff you probably already know but thought I would post it anyway.
Cases up in some states but hospitalization rates down. What does that tell you? It’s possible Covid19 is losing some potency? Correlation is there between new case increases but lower hospitalizations. It happen with SARS, it might be happening with Covid19.Effective. Look at the states that had weak stay-at home orders in the South, and South-west. Cases really starting to rise.
Cases up in some states but hospitalization rates down. What does that tell you? It’s possible Covid19 is losing some potency? Correlation is there between new case increases but lower hospitalizations. It happen with SARS, it might be happening with Covid19.
+1Cases up in some states but hospitalization rates down. What does that tell you? It’s possible Covid19 is losing some potency? Correlation is there between new case increases but lower hospitalizations. It happen with SARS, it might be happening with Covid19.
+1
It is rapidly mutating into a weaker form in Italy/EU already. It will happen here as well.
LolWHO changes guidelines and says people should wear masks in public where social distancing not possible.
From the article:
The World Health Organization (WHO) has changed its advice on face masks, saying they should be worn in public where social distancing is not possible to help stop the spread of coronavirus.
The global body said new information showed they could provide "a barrier for potentially infectious droplets".
Some countries already recommend or mandate face coverings in public.
The WHO had previously argued there was not enough evidence to say that healthy people should wear masks.
However, WHO director-general Dr Tedros Adhanom Ghebreyesus said on Friday that "in light of evolving evidence, the WHO advises that governments should encourage the general public to wear masks where there is widespread transmission and physical distancing is difficult, such as on public transport, in shops or in other confined or crowded environments".
The organisation had always advised that medical face masks should be worn by people who are sick and by those caring for them.
The organisation said its new guidance had been prompted by studies over recent weeks.
Dr Maria Van Kerkhove, the WHO's technical lead expert on Covid-19, told Reuters news agency the recommendation was for people to wear a "fabric mask - that is, a non-medical mask".
Fabric masks should consist of "at least three layers of different material" in order to be effective, the WHO says.
However, those aged over-60 and with underlying health risks should wear medical masks in areas where there is community transmission.
At the same time, the WHO stressed that face masks were just one of a range of tools that could be used to reduce the risk of transmission - and that they should not give people a false sense of protection.
"Masks on their own will not protect you from Covid-19," Dr Tedros said.
This is a big shift in the WHO's guidance on when the public should cover their faces. For months, the organisation's experts stuck to the line that masks would encourage a false sense of security and would deprive medical professionals of badly needed protective equipment.
Those arguments have not gone away but at the same time the WHO acknowledges that new evidence has emerged on the risks of transmission.
It points to recent research that people can be highly infectious in the few days before they show symptoms and that some people catch the virus but never show symptoms at all, as I reported last weekend.
So where distancing is not possible, such as on public transport and in locations as varied as shops and refugee camps, it is suggested that faces are covered with homemade masks to avoid passing on the infection.
Over 60s with underlying health conditions should go further, the WHO said, and wear medical-grade masks to give themselves better protection.
https://www.bbc.com/news/health-52945210
The WHO have not distinguished themselves in this pandemic, as they were late to call it a pandemic, weren't forceful enough with China and now have put out this flawed guidance on masks. But even if one didn't criticize the WHO before is irrelevant to whether one would criticize them over this highly flawed directive on masks. As several experts have posited, it's very likely they're simply acknowledging there aren't enough masks for everyone in the world (especially some of the harder hit 3rd world countries) and trying to preserve masks for health care workers - however, they could have worked some wording to that effect into the guidance.
WHO changes guidelines and says people should wear masks in public where social distancing not possible.
From the article:
The World Health Organization (WHO) has changed its advice on face masks, saying they should be worn in public where social distancing is not possible to help stop the spread of coronavirus.
The global body said new information showed they could provide "a barrier for potentially infectious droplets".
Some countries already recommend or mandate face coverings in public.
The WHO had previously argued there was not enough evidence to say that healthy people should wear masks.
However, WHO director-general Dr Tedros Adhanom Ghebreyesus said on Friday that "in light of evolving evidence, the WHO advises that governments should encourage the general public to wear masks where there is widespread transmission and physical distancing is difficult, such as on public transport, in shops or in other confined or crowded environments".
The organisation had always advised that medical face masks should be worn by people who are sick and by those caring for them.
The organisation said its new guidance had been prompted by studies over recent weeks.
Dr Maria Van Kerkhove, the WHO's technical lead expert on Covid-19, told Reuters news agency the recommendation was for people to wear a "fabric mask - that is, a non-medical mask".
Fabric masks should consist of "at least three layers of different material" in order to be effective, the WHO says.
However, those aged over-60 and with underlying health risks should wear medical masks in areas where there is community transmission.
At the same time, the WHO stressed that face masks were just one of a range of tools that could be used to reduce the risk of transmission - and that they should not give people a false sense of protection.
"Masks on their own will not protect you from Covid-19," Dr Tedros said.
This is a big shift in the WHO's guidance on when the public should cover their faces. For months, the organisation's experts stuck to the line that masks would encourage a false sense of security and would deprive medical professionals of badly needed protective equipment.
Those arguments have not gone away but at the same time the WHO acknowledges that new evidence has emerged on the risks of transmission.
It points to recent research that people can be highly infectious in the few days before they show symptoms and that some people catch the virus but never show symptoms at all, as I reported last weekend.
So where distancing is not possible, such as on public transport and in locations as varied as shops and refugee camps, it is suggested that faces are covered with homemade masks to avoid passing on the infection.
Over 60s with underlying health conditions should go further, the WHO said, and wear medical-grade masks to give themselves better protection.
https://www.bbc.com/news/health-52945210
There is no proof of that yet.
You won’t hear it on MSM news but there are doctor’s reporting the same in New York ... it is possible at least according to NYU Langone.There is no proof of that yet.
Can't it be both? The restrictions got us to where we are today and it's past due to open things up quicker. I've questioned Murphy's comment about the science dictating what opens. I still don't understand what science said Walmart could remain open with restrictions but Kohls couldn't stay open with the same restrictions. Many other states have opened quicker without dire consequences.7 straight days below 1000 new cases for NJ.
Reason to say restrictions thus far have proven effective, or reason to argue opening up is way over due?
If that's real, it makes no sense and is more proof that many of these decisions are political.How does this make any sense?
#privilegeAgree- why is it ok for 10,000 folks to protest but not 10,000 folks to attend a baseball or football game?
So once again, the WHO pivots two weeks too late. What good is a global advisory board if the Federal governments cannot look to it for timely, accurate guidance?WHO changes guidelines and says people should wear masks in public where social distancing not possible.
From the article:
The World Health Organization (WHO) has changed its advice on face masks, saying they should be worn in public where social distancing is not possible to help stop the spread of coronavirus.
The global body said new information showed they could provide "a barrier for potentially infectious droplets".
Some countries already recommend or mandate face coverings in public.
The WHO had previously argued there was not enough evidence to say that healthy people should wear masks.
However, WHO director-general Dr Tedros Adhanom Ghebreyesus said on Friday that "in light of evolving evidence, the WHO advises that governments should encourage the general public to wear masks where there is widespread transmission and physical distancing is difficult, such as on public transport, in shops or in other confined or crowded environments".
The organisation had always advised that medical face masks should be worn by people who are sick and by those caring for them.
The organisation said its new guidance had been prompted by studies over recent weeks.
Dr Maria Van Kerkhove, the WHO's technical lead expert on Covid-19, told Reuters news agency the recommendation was for people to wear a "fabric mask - that is, a non-medical mask".
Fabric masks should consist of "at least three layers of different material" in order to be effective, the WHO says.
However, those aged over-60 and with underlying health risks should wear medical masks in areas where there is community transmission.
At the same time, the WHO stressed that face masks were just one of a range of tools that could be used to reduce the risk of transmission - and that they should not give people a false sense of protection.
"Masks on their own will not protect you from Covid-19," Dr Tedros said.
This is a big shift in the WHO's guidance on when the public should cover their faces. For months, the organisation's experts stuck to the line that masks would encourage a false sense of security and would deprive medical professionals of badly needed protective equipment.
Those arguments have not gone away but at the same time the WHO acknowledges that new evidence has emerged on the risks of transmission.
It points to recent research that people can be highly infectious in the few days before they show symptoms and that some people catch the virus but never show symptoms at all, as I reported last weekend.
So where distancing is not possible, such as on public transport and in locations as varied as shops and refugee camps, it is suggested that faces are covered with homemade masks to avoid passing on the infection.
Over 60s with underlying health conditions should go further, the WHO said, and wear medical-grade masks to give themselves better protection.
https://www.bbc.com/news/health-52945210
how phony was a bunch of health officials saying that people congregating for protests was not a threat of spreading coronavirus but people congregating for other reasons was, did they actually do that...that is why people are skeptical of anything that health officials and scientists and politicians tell us, when they try putting out a statement like that, it just makes your brain fry seeing this kind of pretezel logic. And this isnt a political post, its an observation
from the now-deleted thread...
This from a guy who started his own CoVid thread on the football board because his political motivations could not be questioned there.
The CE board is gone because of liberal whining and you talk about whining.
1882 today. Net change is -100 last two days. Forbidding restaurants, retail, wineries, other outdoor businesses from earning revenue next weekend if they can do it safely is state mandated theft at this point.Hospitalizations statewide down to 1933.
No, but there is absolute proof that T is a troll. This article should be required reading for folks who say the virus is weakening. Of course it could happen, but there's no evidence to that effect yet, especially given a much slower mutation rate than the flu, for example, and perfectly good explanations to observations like decreased death rates (since worldwide case rates are up), as per the excerpt below.There is no proof of that yet.
US announces "Warp Speed" a plan to have 300MM doses of a commercially available vaccine (or multiple vaccines) by the end of the year. I love the enthusiasm, financial/scientific support, and audacity of it all, but am troubled by the US first approach, given that this is a worldwide pandemic that needs a global solution IMO, the potential to shortchange safety, and the decision to not collaborate at all with the Chinese, especially if they end up being first with a vaccine.
https://www.sciencemag.org/news/202...ouse-s-america-first-push-coronavirus-vaccine
Warp Speed has already narrowed its list of vaccine candidates to 14 and plans to push ahead with eight, the official says. “The idea for us is to pick a diversified portfolio” of vaccines made with different technologies, or platforms. Organizers were concerned that other government vaccine investment has been “heavily weighted” toward just two candidates: one made with messenger RNA encoding the coronavirus surface “spike” protein and the other using a cold-causing adenovirus to deliver the same protein’s gene. Neither technology, the official notes, has yet led to approved vaccines for any disease.
The official declined to identify Warp Speed’s vaccine candidates, but he stressed two key criteria: safety and the potential to make hundreds of millions of doses quickly. “We don’t have time to debug manufacturing issues here,” he says. By July, Warp Speed hopes to have its eight lead candidates in human trials. At the same time, it will fund a large-scale comparison of their safety and efficacy in hamsters and monkeys to help winnow down that group. “If something’s really bad, we’ll get rid of it,” he says.
In parallel with the trials, the project will lay the groundwork for “heavy duty manufacturing” of as many as four different vaccines. More than one may prove worthy, and multiple options guard against contamination incidents and other supply concerns.
Wrong hospitalizations are increasing in a number of statesCases up in some states but hospitalization rates down. What does that tell you? It’s possible Covid19 is losing some potency? Correlation is there between new case increases but lower hospitalizations. It happen with SARS, it might be happening with Covid19.
LOL classic coming from you. They arent btwWrong hospitalizations are increasing in a number of states
They are despite what your trolling saysLOL classic coming from you. They arent btw
Please become a scientist and run your own study. Your obsession with hcq is bizzareThe issue with Boulware's study is the subgroups Day1 thru 4 are underpowered to determine interactions between HCQ on Days 1-4. Especially Day 1After Exposure with only 77 evals. I did a hypothetical evaluation where I added 46 obs to Day 1 HCQ with 3 positives to have 8/123 instead of 5/77 same IR 6.5. The interaction analysis is significant to 95%. Which means their is a significant effect between when treatment started. If the subgroups were sufficiently powered it might have actually proved early HCQ worked as post-exposure prophylactic.
To summarize their data hints at a significant effect between when treatment started but was not sufficiently powered to detect significance. If the subgroups were sufficiently powered it might have actually proved early HCQ worked as post-exposure prophylactic if given 1 day or less after exposure.
I posted these many of these thoughts on twitter yesterday. Look what I found: An article suggesting similar conclusions. Go to link and click view on AMP Mobile link to get details similar to mine.
https://t.co/LtkOssIWkS?amp=1
Boulware's conclusion is debatable and most definitely not categorical. In fact his data hints to a possible effect of early HCQ in post-exposure prophylaxis.
Or what he said isn’t true, which it isn’tor maybe younger people are getting it more than old people because young people are out and about and the old are being more careful.
SIAP, but thought this was an interesting article updating the US's "Warp Speed" vaccine development program. As I said a month ago, love the enthusiasm, scientific firepower and financial support involved with the project, but have concerns over a few things, as per the article.
Specifically, the apparent lack of coordination with BARDA, the government’s Biomedical Advanced Research Development Authority and more importantly, the fact that we're not including even one vaccine candidate featuring the tried and true weakened or inactivated virus approach (used in many/most vaccines). And, of course, safety is going to be a major issue for any vaccine developed over such a short timeframe - it can certainly be done safely, but speed and safety usually don't go together.
https://www.sciencemag.org/news/202...te-house-selection-covid-19-vaccine-shortlist
Inactivated, whole SARS-CoV-2 is the basis of four of the 10 vaccines that have advanced to human trials around the world, including one that worked well in a monkey study. But all four are made in China. As Science revealed earlier, Warp Speed explicitly would not consider any vaccines made in China.
Yes, China has several such candidates and we're apparently not going to pursue any. I'd at least want to have one "old school" vaccine candidate, as we know that approach should work. Imagine the hue and cry if our "modern" vaccine approaches fail and China's succeeds...Are any of the leading vaccines using a the weakened form of the virus approach?
Yes, China has several such candidates and we're apparently not going to pursue any. I'd at least want to have one "old school" vaccine candidate, as we know that approach should work. Imagine the hue and cry if our "modern" vaccine approaches fail and China's succeeds...
Did you know that sometimes you can have sex without a condom and not get the woman pregnant.Masks are like a condom with holes in them. Not all of it gets out but she still is getting pregnant.
I'm on the other side of the fence on the covid topic, but I agree with your point here.how phony was a bunch of health officials saying that people congregating for protests was not a threat of spreading coronavirus but people congregating for other reasons was, did they actually do that...that is why people are skeptical of anything that health officials and scientists and politicians tell us, when they try putting out a statement like that, it just makes your brain fry seeing this kind of pretezel logic. And this isnt a political post, its an observation
Well we don't know if the numbers would have dipped this low if Murphy had opened up earlier. So maybe it could be both, but maybe not, we can't say, we do know that with restrictions in place the #'s came way down.Can't it be both? The restrictions got us to where we are today and it's past due to open things up quicker. I've questioned Murphy's comment about the science dictating what opens. I still don't understand what science said Walmart could remain open with restrictions but Kohls couldn't stay open with the same restrictions. Many other states have opened quicker without dire consequences.
Allow these restaurants to open to customers with restrictions. I've eaten at some places with a lot of space and it would be easy to allow some indoor seating along with outdoor. This could be the difference between saving a business or letting it fold. For those who aren't comfortable, simply don't go but adults can make the decision instead of Murphy.
I don't think it was just people on the right criticizing her. Many people wanted to do home improvement projects since they were being told by our politicians they had to stay home. I didn't hear of any other state allowing a store to be open but then restricting what part of the store could be patronized and this goes back to my earlier comments about what science says rules like this would help "flatten the curve".Well we don't know if the numbers would have dipped this low if Murphy had opened up earlier. So maybe it could be both, but maybe not, we can't say, we do know that with restrictions in place the #'s came way down.
As per Walmart vs Kohl's, Walmart sells food, and I assume other essential goods thus they were considered essential. It's a unfortunate loophole which then allowed them to sell other goods. And this was why the Michigan governor tried to restrict sales like paint in stores like Home Depot. Kind of made sense, but she was roundly criticized by the right.