It’s bound to fail and just a bad idea . Still lag behind getting out the first dose never mind a 2nd. Poor planning all around at every level.Let’s trust the people to do the right thing. Isn’t that right Ms. Perischelli?
OT: COVID Science - Pfizer/Moderna vaccines >90% effective; Regeneron antibody cocktail looks very promising in phase II/III trial and more
- Thread starter RU848789
- Start date
- Status
You still think contract tracing will be possible after vaccinating several million. Good luck with that idea.
I don’t know if you’ve answered this in these threads and results of JNJ still have to come out but assume they will at least be satisfactory...if you had a choice of vaccine PFE, Moderna, JNJ, AZ which would you choose?
If the gov feels the inventory is normalizing and predictable, then they should absolutely administer the vaccines that are currently reserved. Would be crazy not to.
It sounds like this is exactly what will be occurring. The doses won't be held back, with the hopefully correct assumption manufacturing will meet demand for the second doses. Just saw the news on CNBC.
www.cnbc.com
Separate issue, but I saw that NYC just announced that Citi Field will be a 24/7, 7 days a week vaccine location.
CDC expands Covid vaccination guidelines to everyone 65 and older
The states' focus on vaccinating health-care workers and nursing homes has created a bottleneck, the official said.
Separate issue, but I saw that NYC just announced that Citi Field will be a 24/7, 7 days a week vaccine location.
The Future of the Coronavirus? An Annoying Childhood Infection (Published 2021)
Once immunity is widespread in adults, the virus rampaging across the world will come to resemble the common cold, scientists predict.
This is what I have been talking about as far as optimizing injections. Moderna and Pfizer appear to be producing 60 million doses a month. Sequenced that’s 60 million administered with 30 million full inoculations a month. If and when JJ comes on line how many will they produce per month? Theirs will be a 1 dose so could see a bug ramping there.It sounds like this is exactly what will be occurring. The doses won't be held back, with the hopefully correct assumption manufacturing will meet demand for the second doses. Just saw the news on CNBC.
CDC expands Covid vaccination guidelines to everyone 65 and older
The states' focus on vaccinating health-care workers and nursing homes has created a bottleneck, the official said.
Separate issue, but I saw that NYC just announced that Citi Field will be a 24/7, 7 days a week vaccine location.
Why not call up national guard to help admin doses quickly at locations throughout? Just an idea.
It sounds like this is exactly what will be occurring. The doses won't be held back, with the hopefully correct assumption manufacturing will meet demand for the second doses. Just saw the news on CNBC.
CDC expands Covid vaccination guidelines to everyone 65 and older
The states' focus on vaccinating health-care workers and nursing homes has created a bottleneck, the official said.
Separate issue, but I saw that NYC just announced that Citi Field will be a 24/7, 7 days a week vaccine location.
Can you mix and match vaccines. Don’t believe so.
I guess no baseball this year.It sounds like this is exactly what will be occurring. The doses won't be held back, with the hopefully correct assumption manufacturing will meet demand for the second doses. Just saw the news on CNBC.
CDC expands Covid vaccination guidelines to everyone 65 and older
The states' focus on vaccinating health-care workers and nursing homes has created a bottleneck, the official said.
Separate issue, but I saw that NYC just announced that Citi Field will be a 24/7, 7 days a week vaccine location.
I consider the two mRNA vaccines as being essentially identical, so I'd take one of those, since they have higher demonstrated efficacy than the Astra-Zeneca vaccine, which also still has a number of oddities and questions surrounding it, as have been discussed before (post below, including Derek Lowe's take), plus they're the only two approved so far in the US. And we have no idea, yet, on what the J&J results will be. If it's close to the ~95% effectiveness of the mRNA vaccines I might pick that one, as it's a single shot.
There will be baseball this year. Even if we "only" have 75-100MM vaccinated by April, that, combined with a pretty high number of infected/recovered/immune people by then (30%?), that's a much better place than we were in this past year where we had baseball and other sports. The bigger question is fans. I'm hoping we'll have more data on low transmission rates from vaccinated people by then, which would make it very likely vaccinated (and probably recovered/immune) fans could attend.
My wife , son and I went to two Somerset patriot games last season. They had a series of exhibition games against the NJ Blasters. It was fun. The Patriots won the series and got the Joe Torre trophy, the best pitcher got the Sparky Lyle trophy and the series MVP got the Willie Randolph trophy .They only allowed 500 people in per game and they did sell out each game. The Sussex Miners and NJ Jackels also did something similar . I don't know if fans were allowed. My feeling is baseball will be played . Too much money to lose again if they don't. They will figure it out.
I hope you are right. I dont see a 100 million before April. Most of these "mega-centers" we are seeing now can only vaccinate 2,500 max a day. NJ only has current plans of just 6 of them. That is not nearly enough. Its been a horrible start.
CVS has 20000 stores and who knows how many Walgreens. I agree poor planning at the top. Give it to the states and let 50 of them figure it out.
Not all of those stores have the deep freezers. We seen many examples of wasted vaccines because of that.
It has been given to the states! That is where the plans failed, at the state level.
wait only a year....hahaha.....$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$
www.forbes.com
Moderna Says Its Covid-19 Vaccine Provides One Year’s Immunity
The U.S. has ordered 200 million doses of the Moderna vaccine, enough to immunize 100 million people.
www.forbes.com
US to require all arriving passengers to get COVID-19 test
The CDC order is to take effect in about two weeks, on Jan. 26. It requires air passengers to get a COVID-19 test within three days before their flight departs to the U.S., and to provide written proof of the test result to the airline. Travelers can also provide documentation that they had the infection in the past and recovered.
Airlines are ordered to stop passengers from boarding if they don’t have proof of a negative test or a prior infection.
www.pix11.com
The CDC order is to take effect in about two weeks, on Jan. 26. It requires air passengers to get a COVID-19 test within three days before their flight departs to the U.S., and to provide written proof of the test result to the airline. Travelers can also provide documentation that they had the infection in the past and recovered.
Airlines are ordered to stop passengers from boarding if they don’t have proof of a negative test or a prior infection.
US to require all arriving passengers to get COVID-19 test
Anyone flying to the U.S. will soon need to show proof of a negative test for COVID-19, health officials announced Tuesday. The Centers for Disease Control and Prevention requirement expands on a s…
www.pix11.com
Which is stupid. Getting a test means at that moment you have it or not. It doesn't actually mean you don't have it as we see false negatives and within 3 days anyone can get it.US to require all arriving passengers to get COVID-19 test
The CDC order is to take effect in about two weeks, on Jan. 26. It requires air passengers to get a COVID-19 test within three days before their flight departs to the U.S., and to provide written proof of the test result to the airline. Travelers can also provide documentation that they had the infection in the past and recovered.
Airlines are ordered to stop passengers from boarding if they don’t have proof of a negative test or a prior infection.
US to require all arriving passengers to get COVID-19 test
Anyone flying to the U.S. will soon need to show proof of a negative test for COVID-19, health officials announced Tuesday. The Centers for Disease Control and Prevention requirement expands on a s…
Been talking a lot about the future of SARS-CoV-2 lately, especially with regard to whether variants will emerge which vaccines or previous COVID infections won't provide immunity to (not yet and hopefully not for awhile), as well as whether the virus will eventually "disappear" like SARS/MERS (previous similar coronaviruses) or become endemic, but probably mostly harmless, like a host of existing coronaviruses that cause the common cold.
Well today a paper came out from Lavine, et al, on the topic of endemicity, entitled, "Immunological characteristics govern the transition of COVID-19 to endemicity," which is getting a lot of attention among scientists and even the mainstream press. Basically, they're predicting that COVID will eventually become endemic and likely no more virulent than the common cold, but they talk a lot about the path to get there being far less deadly if this endpoint is reached via vaccination rather than transmission. An excerpt from their abstract is below.
https://science.sciencemag.org/content/early/2021/01/11/science.abe6522
We are currently faced with the question of how the CoV-2 severity may change in the years ahead. Our analysis of immunological and epidemiological data on endemic human coronaviruses (HCoVs) shows that infection-blocking immunity wanes rapidly, but disease-reducing immunity is long-lived. Our model, incorporating these components of immunity, recapitulates both the current severity of CoV-2 and the benign nature of HCoVs, suggesting that once the endemic phase is reached and primary exposure is in childhood, CoV-2 may be no more virulent than the common cold.
Since the paper is certainly pretty dense and complex, it might also be worth reading the article in today's Times by science writer Apoorva Mandavalli, who is truly excellent. She talks more about how we get there in the article, as per the excerpt below. As i've said countless times, if we rely on transmission to get us to "herd immunity" and are only 20-30% of the way there now with 380K deaths, getting to 70-80% infected, where transmissions woud likely end on their own would likely mean another 500K+ deaths and millions of serious illnesses - that's why vaccinating as fast as we can is so important in the US and worldwide.
https://www.nytimes.com/2021/01/12/health/coronavirus-immunity-future.html
In other words, the coronavirus will become “endemic,” a pathogen that circulates at low levels and only rarely causes serious illness.
“The timing of how long it takes to get to this sort of endemic state depends on how quickly the disease is spreading, and how quickly vaccination is rolled out,” said Jennie Lavine, a postdoctoral fellow at Emory University in Atlanta, who led the study.
“So really, the name of the game is getting everyone exposed for the first time to the vaccine as quickly as possible.”
And another really good paper came out today in the prestigious journal Cell, this time from Crotty and Settes (Crotty did the great paper a few months ago on profiling immune responses in infected/recovered patients, posted above), providing a great overview of the literature, to date, on the adaptive immune system and its role in COVID infections and vaccines. If you ever wanted to know anything about the human immune system and how it fights viral infections, it's probably either in here or in the bibliography. The summary is below. I assume @UMRU is all over this one. 😄
https://www.sciencedirect.com/science/article/abs/pii/S0092867421000076
Summary: While there is much more to be learned about adaptive immune responses to SARS-CoV-2 and their relationships to disease severity, immune memory, protection, and vaccines, an extraordinary amount has been accomplished during 2020. Studies of antigen-specific CD4+ T cells, CD8+ T cells, and antibodies together in larger cohorts of acute patients, representing a range of disease severity, are needed to further understand mechanisms of protective adaptive immune responses to COVID-19. Big unknowns remain about variable kinetics of viral loads and duration of infection and the connections between those parameters and adaptive immunity and immune memory. Understanding heterogenous disease manifestations of COVID-19 remains a major knowledge gap, and exploring relationships between those phenomena and adaptive immunity is a priority. Additionally, duration of immune memory, and protective immunity, to SARS-CoV-2 after COVID-19 and in response to COVID-19 vaccines will be a high priority for years to come.
Last edited:
It's not perfect, but it probably cuts out at least half the infectious people who might otherwise be traveling - it's 100x better than screening for temperature.
Got my second pfizer vaccine dose today, just a little soreness at injection site.
Shocker...NOT
www.cnn.com
Chinese Covid-19 vaccine far less effective than initially claimed in Brazil, sparking concerns | CNN
A leading Chinese Covid-19 vaccine developed by Sinovac Biotech was just 50.38% effective in late-stage trials in Brazil, significantly lower than earlier results showed, according to a statement published by the government of Sao Paulo Tuesday.
Yep, think that’s from the same paper numbers posted about.
I laugh at this BS.
That's because an immunized person can still potentially...
Nobody knows this as fact. So they rather you catch the virus first than get vaccinated.
See this article and make sure you register on the site (link included in article)
N.J. to expand COVID vaccine eligibility to people 65 and older, Murphy says
Gov. Phil Murphy said the state will comply with the CDC's new guidelines for coronavirus vaccinations and expand eligibility within days.
Sorry Armin., I referenced the wrong post. Do you have a source for this post? I am not being critical, I am only trying to get reliable information about vaccine availability to 1B people. I was told by my town Health Department yesterday that they are still doing !A category and had no idea when 1B would begin.
No worries! See my reply above.
Murphy will be having his Wednesday press conference soon, so more info will be coming out this afternoon as well.
If you’re interested, they live stream the video conference on the nj.com Facebook page.
Last edited:
Some real life anecdotal information. Spoke to a group who owns 100 senior housing assisted living/ memory care facilities in the US with 12000 residents.
Partnered with CVS to conduct clinics. 35% of the way through senior population and expect to be finished with second dose by mid March. Have seen 95 to 100 percent acceptance.
Healthcare workers acceptance 50% as the majority are in child bearing years. 80% workforce is female and that concern is the biggest expressed by those not getting vaccinated. Lack of data. Younger men have also expressed this concern.
they cannot mandate it as they would have a problem with finding qualified people to work in these facilities. If they had 90% acceptance they could likely make it mandatory.
Partnered with CVS to conduct clinics. 35% of the way through senior population and expect to be finished with second dose by mid March. Have seen 95 to 100 percent acceptance.
Healthcare workers acceptance 50% as the majority are in child bearing years. 80% workforce is female and that concern is the biggest expressed by those not getting vaccinated. Lack of data. Younger men have also expressed this concern.
they cannot mandate it as they would have a problem with finding qualified people to work in these facilities. If they had 90% acceptance they could likely make it mandatory.
JNJ efficacy coming next week for sure. Slaoui is guessing 80%. At this point things are likely unblinded and he’s definitely catching some whispers. I’m guessing it will be 70-80% for at least the 18-65 cohort. Older than that this vaccine may struggle a bit based on some of the results outlined in the nejm paper that was released today.
Do we know how many doses they can produce and how quickly?
Disregard question. Found this. Looks like they are behind but could get to 60 million by February.
Redirect Notice
www.google.com
I'm sort of hoping that by the time I'm cleared to get one (40 yo, no medical issues) I'll be getting the JJ one dose vax.
Don’t think Feb, 60mil by April and they are trying to pull that in so they hit that mark sometime in March. At least that’s what the article says. Yesterday they were saying they’ll only be in the single digit millions for Feb, but trying to get into double digits,
Yup mistype. April. Was hoping they would have been able to ramp quicker than that.
- Status
