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COVID-19 Pandemic: Transmissions, Deaths, Treatments, Vaccines, Interventions and More...

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Had never heard of this one - going to see a lot of announcements like this in coming weeks about drug treatments being carried out under emergency investigational new drug applications. Some promising, but very small scale results with leronlimab (CCR5 antagonist - I worked on one of those years ago and I bet the old ones are being pulled off the shelves all over pharma) in

Leronlimab Used in Seven Patients with Severe COVID-19 Demonstrated Promise with Two Intubated Patients in ICU, Removed from ICU and Extubated with Reduced Pulmonary Inflammation

VANCOUVER, Washington, March 27, 2020 (GLOBE NEWSWIRE) -- CytoDyn Inc. (OTC.QB: CYDY), (“CytoDyn” or the “Company"), a late-stage biotechnology company developing leronlimab (PRO 140), a CCR5 antagonist with the potential for multiple therapeutic indications, announced today the three-day results post-leronlimab treatment of the first four patients under an Emergency Investigational New Drug (EIND) granted by the U.S. Food and Drug Administration (FDA). A total of seven patients have been enrolled thus far under EIND in the same leading medical center in the New York City area.


https://www.cytodyn.com/newsroom/pr...b-used-in-seven-patients-with-severe-covid-19
 
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You people are insane about washing your cash and mail. I see a typical Twilight Zone episode where are peeps are so set on being ultra germ free that they slip and end up getting sick. Like to see some of you guys wash pinepples.
 
Very insightful interview with one of the lead Chinese scientists who has been working on this epidemic since day one (and helped decode the virus's RNA sequence); Science has tried to interview George Gao, director-general of the Chinese Center for Disease Control and Prevention (CDC), for 2 months. Most interesting comment from him might be that he thinks our biggest mistake in the US and other Western countries has been not wearing masks to reduce the chances of infected people (many of whom are asymptomatic) infecting others in public. Been saying that for at least a month...

https://www.sciencemag.org/news/202...avirus-big-mistake-top-chinese-scientist-says

But, but, but, Debbie Birx said we dont need masks. What say you Bac? You wanted to listen to the expert despite practical reasoning, remember?

I appreciate your response, numbers.

I enjoy the fact, this dude isnt even referred to by his name..he is #s, numbers, or RU#. That's awesome..but not as awesome as the info he puts out for us. Thank you RU#.
 
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But, but, but, Debbie Birx said we dont need masks. What say you Bac? You wanted to listen to the expert despite practical reasoning, remember?



I enjoy the fact, this dude isnt even referred to by his name..he is #s, numbers, or RU#. That's awesome..but not as awesome as the info he puts out for us. Thank you RU#.

You sound angry bro
 
The more this goes on the more I think this is all about waiting till you catch it and hoping your one of those people who doesn't have a bad reaction.

Side note, how common is it for a virus to have such a wide spread of symptoms?
 
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Instant song of the year nomination. Hell, just name it song of the year right now. Man did I need to hear something funny today:

 
News reports indicate he is projecting the need for ventilators over the next few weeks as the number of Covid-19 cases continues to grow exponentially, even if the state has enough to meet today's demand.
Actually watching his presser from this afternoon and he explains exactly this. A summation of his point on this:

We have been behind this thing from the get go, NYC's apex is 14-21 days from now, so by asking for ventilators now, he is trying to get ahead of this thing.
 
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We mostly do, except onions, garlic and oranges, apples and bananas, all of which are easy to wash. We do canned/frozen for harder to wash ones.
You don’t eat the skin of an orange or banana so I don’t think that should be much of a problem. You can peel an apple too but I just wash and scrub those down with water. The skin has all the healthy nutrients so I don’t want to peel it. Not fond of the idea of soap and food. Different soaps have different harshness too. Saw an article in nj.com not recommending it but I have seen others recommending it. It’s really only the stuff that might be eaten raw that should be any worry. If you’re going to cook said food it should be fine as that will kill the virus and whatever else.

Washing and other grocery recommendations are in the article.

From the article:

You should wash your fruits and veggies, but not with soap
Washing fresh fruits and vegetables is good advice all the time. But don’t use soap.

“Soap should absolutely not be used to wash food. It’s not designed for that. Soap can cause nausea, vomiting and diarrhea if ingested,” Schaffner said.

Rinsing fruits and vegetables with cold water before peeling them is best practice, the FDA says.

“You should always wash (fruits and vegetables), it’s not something new with this coronavirus,” Krummenacher said. "It can help clear away all types of viruses that live on food, not just the coronavirus.

There have been no studies done to see how long the coronavirus lives on fruits and vegetables, he said.


https://www.nj.com/coronavirus/2020...-dont-leave-them-outside-nj-experts-warn.html
 
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You people are insane about washing your cash and mail. I see a typical Twilight Zone episode where are peeps are so set on being ultra germ free that they slip and end up getting sick. Like to see some of you guys wash pinepples.
It’s pretty easy to go cashless.

It’s the washing of groceries that’s a complete pain point for me personally.

I mean it’s only once a week, but if someone has a good idea, I’m always looking for ways to run the household more efficiently.
 
You sound angry bro

Not angry at all...I'm good, family is good. Two glasses of wine, a can of Magnify - Only a Spark...and I am copacetic. When people don't listen to practical advice but hedge their bets on an experts sitting behind a desk/podium that can be a problem. Even despite hard, empirical and practical evidence that disputes said expert. Now another expert (who's country appears to have corralled Covid-19) is disputing an expert who's country may get its ass handed to them very soon....who do ya believe now? Expert 1, or Expert 2 (plus the overwhelmingly vast majority of healthcare professionals who side with Expert 2)?
 
Not angry at all...I'm good, family is good. Two glasses of wine, a can of Magnify - Only a Spark...and I am copacetic. When people don't listen to practical advice but hedge their bets on an experts sitting behind a desk/podium that can be a problem. Even despite hard, empirical and practical evidence that disputes said expert. Now another expert (who's country appears to have corralled Covid-19) is disputing an expert who's country may get its ass handed to them very soon....who do ya believe now? Expert 1, or Expert 2 (plus the overwhelmingly vast majority of healthcare professionals who side with Expert 2)?

Ill take USA over China everyday
 
You people are insane about washing your cash and mail. I see a typical Twilight Zone episode where are peeps are so set on being ultra germ free that they slip and end up getting sick. Like to see some of you guys wash pinepples.
I’ve said this before I’m a somewhat germphobe and even I can only go so far. It’s just too tiring frankly lol. I save my bandwidth for high traffic touch things like door knobs, grocery cart handles and remotes, etc. Those are all things I’ve done in the past before this and now I do with more frequency and I’ve added grocery now if it’s been delivered because of the gloves they use to handle. There’s really only so much I can do or I’ll go cuckoo haha. So I focus on certain aspects that I think are worthwhile and try my best but beyond that whatever happens happens. There’s a balance between risk/benefit and mental sanity lol.
 
Did we not care about swine flu? Why is this being treated different? We had the hospital beds to support swine flu but not this?
 
Did we not care about swine flu? Why is this being treated different? We had the hospital beds to support swine flu but not this?
I don't really know the details, but was the demand for beds for Swine as high as they are going to be for this? And did we have the beds for all those that needed one?
 
From Wiki on Swine: It is estimated that in the 2009 flu pandemic 11–21% of the then global population (of about 6.8 billion), or around 700 million to 1.4 billion people, contracted the illness—more in absolute terms than the Spanish flu pandemic.


The disease then spread across the country's population and by the end of May had infected citizens in all 50 states. The pattern continued through June of the same year. The total number of confirmed cases varied from 27,717 (Centers for Disease Control and Prevention (CDC) confirmed and probable cases) and 25,453 (total of all state confirmed cases) as of June 26, 2009.[122]

Towards the middle of June 2009, the number of US cases surpassed those of Mexico, which had been the previous leader in diagnosed cases of the disease. Toward the end of June 2009, the number of deaths related to the virus in the US surpassed those of all other countries as well.

On June 25, the CDC released information revealing that there were more than likely over one million (1,000,000) cases of the disease in the US, most of which had not been reported or diagnosed

Deaths relating to this new strain of influenza began appearing in the US in late April, and by early June, 15 states had reported fatalities related to or directly occurring from the virus. These deaths totaled at 4,000 as of November 15, 2009. (Later reaching 12,469 American deaths, as of 03/2020 according to the WHO). The CDC distributed a vaccine for the novel flu strain[125] using mechanisms already in place for its Vaccines for Children (VFC) program.[126]

Barack Obama being vaccinated on Dec. 20, 2009.
An official for the White House said on April 24 that "the White House is taking the situation seriously and monitoring for any new developments. The president has been fully briefed."[162] President Barack Obama stated that "We are closely monitoring the emerging cases of swine flu". He also noted, "This is obviously a cause for concern ... but it is not a cause for alarm".[163] President Obama suggested that U.S. schools should consider shutting down, as a future possibility, if their students were to become infected.

FAKE NEWS
 
From Wiki on Swine: It is estimated that in the 2009 flu pandemic 11–21% of the then global population (of about 6.8 billion), or around 700 million to 1.4 billion people, contracted the illness—more in absolute terms than the Spanish flu pandemic.


The disease then spread across the country's population and by the end of May had infected citizens in all 50 states. The pattern continued through June of the same year. The total number of confirmed cases varied from 27,717 (Centers for Disease Control and Prevention (CDC) confirmed and probable cases) and 25,453 (total of all state confirmed cases) as of June 26, 2009.[122]

Towards the middle of June 2009, the number of US cases surpassed those of Mexico, which had been the previous leader in diagnosed cases of the disease. Toward the end of June 2009, the number of deaths related to the virus in the US surpassed those of all other countries as well.

On June 25, the CDC released information revealing that there were more than likely over one million (1,000,000) cases of the disease in the US, most of which had not been reported or diagnosed

Deaths relating to this new strain of influenza began appearing in the US in late April, and by early June, 15 states had reported fatalities related to or directly occurring from the virus. These deaths totaled at 4,000 as of November 15, 2009. (Later reaching 12,469 American deaths, as of 03/2020 according to the WHO). The CDC distributed a vaccine for the novel flu strain[125] using mechanisms already in place for its Vaccines for Children (VFC) program.[126]

Barack Obama being vaccinated on Dec. 20, 2009.
An official for the White House said on April 24 that "the White House is taking the situation seriously and monitoring for any new developments. The president has been fully briefed."[162] President Barack Obama stated that "We are closely monitoring the emerging cases of swine flu". He also noted, "This is obviously a cause for concern ... but it is not a cause for alarm".[163] President Obama suggested that U.S. schools should consider shutting down, as a future possibility, if their students were to become infected.

FAKE NEWS
I'm not sure in which way you mean this?
 
Everybody is clamoring for a vaccine but what about those anti vaxers are they going to get this one or not? Imagine how many flu deaths occur yearly... how many millions in the US become infected even with a vaccine... If you had family loved one who was going to possibly die from covid19 and the only drugs were the 2 being most discussed Hydroxychloroquine and Zithromicin would you ok their use ? The latest discussions by some politicians is they are not safe... not enough information...and don’t want them used... now that is a problem we all should aware of...
 
You don’t eat the skin of an orange or banana so I don’t think that should be much of a problem. You can peel an apple too but I just wash and scrub those down with water. The skin has all the healthy nutrients so I don’t want to peel it. Not fond of the idea of soap and food. Different soaps have different harshness too. Saw an article in nj.com not recommending it but I have seen others recommending it. It’s really only the stuff that might be eaten raw that should be any worry. If you’re going to cook said food it should be fine as that will kill the virus and whatever else.

Washing and other grocery recommendations are in the article.

From the article:

You should wash your fruits and veggies, but not with soap
Washing fresh fruits and vegetables is good advice all the time. But don’t use soap.

“Soap should absolutely not be used to wash food. It’s not designed for that. Soap can cause nausea, vomiting and diarrhea if ingested,” Schaffner said.

Rinsing fruits and vegetables with cold water before peeling them is best practice, the FDA says.

“You should always wash (fruits and vegetables), it’s not something new with this coronavirus,” Krummenacher said. "It can help clear away all types of viruses that live on food, not just the coronavirus.

There have been no studies done to see how long the coronavirus lives on fruits and vegetables, he said.


https://www.nj.com/coronavirus/2020...-dont-leave-them-outside-nj-experts-warn.html
Respectfully disagree. I know soap can do that if not thoroughly rinsed off (which is why I said rinse very thoroughly), but I'd rather risk a little diarrhea than a little coronavirus, especially since we don't have any data on how long the virus can survive on specific fruits/vegetables and most people prefer eating them soon after buying them, which means there could be risk of touching a virus on the produce and then touching one's face and inhaling the virus. If one can wait 3 days (the longest documented time of "survival" of the virus in a controlled experiment, on plastic and stainless steel), then washing is very unlikely to be needed.

The micelle structure of soap with hydrophilic heads (water-loving) and hydrophoboic (water-hating) tails, causes the soap molecules to surround the lipid structure of the virus coat, pulling said coat apart and rupturing the protein of the virus, deactivating it. Soap has the same effect on many bacteria, which can also be an issue with produce, so I'll continue to wash with warm soapy water and rinse with copious amounts of warm water to solubilize the residual soap. Soap and water is also more effective than any hand sanitizer in destroying the viral lipid membrane coat. There are people who know more than some of the people who write things on blogs. Having said that, copious washing with warm water is probably enough to displace most of the surface associated viruses, but I'd rather be 100% sure.

https://www.nytimes.com/2020/03/13/health/soap-coronavirus-handwashing-germs.html
 
I only sanitize perishables, including produce, in a sink filled with warm soapy water (sink makes it a lot easier to contact all the surfaces) and do a really good water rinse; otherwise any surface viruses will last longer than 3 days in cold/frozen conditions. All non-perishables and packages and mail go on a table in the garage that has stuff separated by arrival date and we only open up any of these items after >72 hours (with no precautions, other than chucking all the packaging and washing hands well afterwards), since that's the longest documented (in a controlled study) time virus particles have been observed on stainless steel and polypropylene vs. 1 day on paper/cardboard.

For takeout, we only order warm food (much less likely to sustain any viruses and ingestion isn't a route of infection) and we decon the packaging and plate the food rather than eating out of the containers supplied and, of course we wash hands after plating. It's actually not that much work, especially with the 3-day thing, which greatly reduces sanitizing, as there's almost nothing we need immediately that's non-perishable (we'd sanitize on an exception basis). Also, for takeout, we call ahead and pay over the phone and call when we arrive and have them put the food in the trunk, so no contact occurs (good for both of us). We also get some supplies that way (milk, eggs, bread, lunchmeat, etc.) from the local deli - we order ahead and they drop it in the trunk, as I simply hate going to stores now, due to the risks (and will only go at very late hours when few are around and am trying to figure out how to get everything on line or from locals, but we don't have that 100% covered yet and this could be months for us.

And don't forget, all of the above is important, but not nearly as important as keeping 6+ feet away from people, as >95% of transmissions occur via person to person contact (sneezes, coughs and even breath); fyi, China found that about 80% of transmissions occurred in the household from close contact. Might make a separate thread on this, as the questions keep coming up.
Most scientific experts say rinse fruits and vegetables under running cold water. Not necessary to wash with soap ... actually soap will leave a film even with heavy rinse. When the next disease comes out of China let me know what their scientists think and the recommendations.
 
I rinse oranges and bananas under cold water, then let them sit a few days before peeling and eating.

That OK?
Waiting 3 days should be ok for any surface, including produce. As paranoid as I may be, there's a point beyond which it's likely silly to go further. I mean, it's not like any of us have portable scanning electron microscopes to look for residual viruses, lol...
 
Most scientific experts say rinse fruits and vegetables under running cold water. Not necessary to wash with soap ... actually soap will leave a film even with heavy rinse. When the next disease comes out of China let me know what their scientists think and the recommendations.
Are you going to start arguing the intersection of chemistry and biology with me? You won't win.
 
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Waiting 3 days should be ok for any surface, including produce. As paranoid as I may be, there's a point beyond which it's likely silly to go further. I mean, it's not like any of us have portable scanning electron microscopes to look for residual viruses, lol...

No doctor is saying wait 3 days after washing fruit
 
I’ve said this before I’m a somewhat germphobe and even I can only go so far. It’s just too tiring frankly lol. I save my bandwidth for high traffic touch things like door knobs, grocery cart handles and remotes, etc. Those are all things I’ve done in the past before this and now I do with more frequency and I’ve added grocery now if it’s been delivered because of the gloves they use to handle. There’s really only so much I can do or I’ll go cuckoo haha. So I focus on certain aspects that I think are worthwhile and try my best but beyond that whatever happens happens. There’s a balance between risk/benefit and mental sanity lol.
Oddly enough, I've never been a germ-o-phobe. Generally washed my hands rarely, would eat food off the floor and just never worried about standard germs, since they're all around anyway and I rarely get sick with anything. This is light years different, due to the very high transmission rate of this virus and the serious to potentially deadly effects of it (likely ~10X more deadly than any typical flu). This is the first time I've ever worried about a virus or microbe and am taking far more precautions than I ever have for anything else and until there's a vaccine or effective treatment (antibodies should work, IMO), I will continue to live like this. It's tolerable for us and better than the alternative.
 
Try to keep up - I replied to that link and disagree with it.

Thats your opinion..does not make you right. There are professionals saying otherwise. You are entitled to making your own risk assessments but don't try to come across that your way is the only way to go about it. People can certainly follow your recommendations to be on the safe said but also be aware people get scared when they see these recommendations.
 
Thats your opinion..does not make you right. There are professionals saying otherwise. You are entitled to making your own risk assessments but don't try to come across that your way is the only way to go about it. People can certainly follow your recommendations to be on the safe said but also be aware people get scared when they see these recommendations.
I absolutely guarantee you that warm soapy water is better for coronavirus deactivation and removal from produce than simply rinsing with water, just like it is for hands and any other object that could have surface contamination. That is irrefutable science. However, there is a small risk of gastrointestinal issues from residual soap, which isn't trivial, but for me it's less of a risk than the virus and my risk tolerance is very, very low right now. I do not know exactly how much better it is, though - nobody does - hopefully the difference is small, but I know it's not zero.
 
Do not know if this was posted but this is a must watch. Dr. David Price who works at Weill Cornell Hospital in NYC. Very balanced and concise and alleviates some fears

Hands to your face...hands to your face..hands to your face

Become a Hand Nazi..walk with purell.

Mostly from sustained contact with someone with CoVid

Always know where hands are

Does recommend wearing a mask because you won't touch your face

Do not need a medical mask. N95 masks are for hospitals

Distance yourself in the store

some may think he is downplaying the aerosol risk of catching the virus, but this is a doctor, he is on the frontlines

 
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