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COVID-19 Pandemic: Transmissions, Deaths, Treatments, Vaccines, Interventions and More...

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Looks like most of the coronavirus infections in the NYC area came from people who traveled to NYC from Europe, based on two parallel viral genome studies. This is why travel bans probably only really work in our modern world when the entire world is locked down. Also, given how transmissible the virus now appears to be, there probably is no way it ever could have been stopped, since by the time an outbreak is noticed, asymptomatic people would have always traveled out of the source region. All an earlier lockdown/travel ban would likely have done is delayed the pandemic, not denied it.

The other tidbit from the article is that genome analyses have confirmed that the virus came from bats, not a lab in Wuhan. "Maciej Boni of Penn State University and his colleagues recently used this method to see where the coronavirus, designated SARS-CoV-2, came from in the first place. While conspiracy theories might falsely claim the virus was concocted in a lab, the virus’s genome makes clear that it arose in bats."

https://www.nytimes.com/2020/04/08/...ope-genomes.html?referringSource=articleShare
Just because the virus originated in bats doesn't preclude it being used for research in Wuhan's lab.
 
I just got off the phone with my dad. He is in an assisted living facility in Maryland and the Governor has sent in the National Guard in to try and get things under control. This is happening through the state.

His place has 10 cases in the nursing home part of the facility. They believe a 90 year old contracted it in the hospital and brought it back into the facility.

The bottom line is that even when you think you are being diligent this thing can infiltrate.
And tons of people aren't being diligent. Witnessed lots of older people in Costco during normal hours without protection and not trying to SD.
 
And tons of people aren't being diligent. Witnessed lots of older people in Costco during normal hours without protection and not trying to SD.
Those “ older Folks” were they older say 30 , 40, 50? Do you realize many older seniors don’t have masks or don’t want scarf’s and bandana’s wrapped around their face... now if we are talking under 60-65 then there is the issue.
 
I did not get it from there. In fact I had not seen that until you linked him. That guy is a whacko. I got it on a critical care site discussing these articles:

https://chemrxiv.org/articles/COVID...e_Metabolism_by_Binding_to_Porphyrin/11938173

http://www.techscience.com/cmc/v63n1/38464

Do you have a link to the critical care site? No issue with the two articles above, although the Heme metabolism article is pure bioinformatics modeling based, not experimental, and is far more circumspect about heme metabolism and porphyrin than what you first shared, as one would expect from an actual scientific article.
 
I did not get it from there. In fact I had not seen that until you linked him. That guy is a whacko. I got it on a critical care site discussing these articles:

https://chemrxiv.org/articles/COVID...e_Metabolism_by_Binding_to_Porphyrin/11938173

http://www.techscience.com/cmc/v63n1/38464



wisr01,

i saw you shared that link before and i read it as best i could. had a tough time understanding what it said. not sure if you actually summarized it yourself but did a fantastic job by making it readable. i am not a scientist but the mechanics described makes a whole lotta sense. i watched a vietnamese american doctor explaining what was happening in our lungs on youtube the other day and he said exactly what this article described.

thanks for sharing
 
Ha, ok man. Words matter. It's irresponsible to say that cases are increasing when they're decreasing.
Maybe where you live, or in total they are decreasing. In Mercer County the number of positive cases has increased more than 50% since Saturday.
 
Looks like most of the coronavirus infections in the NYC area came from people who traveled to NYC from Europe, based on two parallel viral genome studies. This is why travel bans probably only really work in our modern world when the entire world is locked down. Also, given how transmissible the virus now appears to be, there probably is no way it ever could have been stopped, since by the time an outbreak is noticed, asymptomatic people would have always traveled out of the source region. All an earlier lockdown/travel ban would likely have done is delayed the pandemic, not denied it.

The other tidbit from the article is that genome analyses have confirmed that the virus came from bats, not a lab in Wuhan. "Maciej Boni of Penn State University and his colleagues recently used this method to see where the coronavirus, designated SARS-CoV-2, came from in the first place. While conspiracy theories might falsely claim the virus was concocted in a lab, the virus’s genome makes clear that it arose in bats."

https://www.nytimes.com/2020/04/08/...ope-genomes.html?referringSource=articleShare

More on the origins of SAS-CoV-2 in the paper linked below, from Nature, where the authors concluded that "genomic analyses clearly show that the virus is not a laboratory construct or a purposefully manipulated virus." The Chinese are guilty of many things in this whole fiasco, including hiding data on the early outbreak and almost certainly not providing complete data on cases/deaths (there's simply no way that China should have about 1/4 the per capita cases as South Korea or 1/2 the total deaths per capita as SK, given there's no way they handled this as well as SK, since they were first and it was far more out of control there), but they didn't purposefully or accidentally make/release this virus.

https://www.nature.com/articles/s41591-020-0820-9

A second paper in preprint delved more into the evolutionary biology of the virus and concluded that "based on evolutionary genomic analysis, scientists estimate that SARS-CoV-2 diverged from other bat-virus lineages 40-70 years ago," which obviously precludes this being the product of laboratory manipulation.

https://www.biorxiv.org/content/10.1101/2020.03.30.015008v1.full
 
Those “ older Folks” were they older say 30 , 40, 50? Do you realize many older seniors don’t have masks or don’t want scarf’s and bandana’s wrapped around their face... now if we are talking under 60-65 then there is the issue.
When I say older I'm talking about those over 60. No one wants to wrap something over their face but we do it out of respect for others and out of desire to protect our own health.
 
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Read my latest post - the virus did not originate in a lab.

OK. Let's try this.

Just because the virus originated in bats and wasn't created in a lab does not preclude it being used for research in Wuhan's lab.

In fact I would be shocked if there are not samples of every coronavirus ever discovered in China in that lab being used for research.
 
fact I would be shocked if there are not samples of every coronavirus ever discovered in China in that lab being used for research.

I am pretty sure that this will be the case for every developed nation around the world. The CDC has strains of almost every disease known to man in storage.
 
Just because the virus originated in bats
We need to get Chick-fil-A to start opening up locations in China!

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When I say I'm talking about those over 60. No one wants to wrap something over their face but we do it out of respect for others and out of desire to protect our own health.
Sure I get it ...protect each other but as I said... many older don’t have masks or just don’t truly understand the reasons... not an excuse but for every senior that adheres to the program just as many who say it is over hyped by the media ... to some extent that may or may not be true... within a year we will have more answers... 95% or perhaps more are following protocols...there have been far more violators in the age groups 25 - 54... if you didn’t see that in this metro area several weeks ago then you have to be naive or oblivious... stay safe and well...seniors should wear masks or scarves simply to protect themselves from the knucklehead crowd.
 
Those “ older Folks” were they older say 30 , 40, 50? Do you realize many older seniors don’t have masks or don’t want scarf’s and bandana’s wrapped around their face... now if we are talking under 60-65 then there is the issue.
In my store I have seen a ton of 70+ yr olds with no face coverings. That has changed a fair amount in recent days, but the idea that they "don't want scarf's around their faces"? Yeah, me neither.
 
Sure I get it ...protect each other but as I said... many older don’t have masks or just don’t truly understand the reasons... not an excuse but for every senior that adheres to the program just as many who say it is over hyped by the media ... to some extent that may or may not be true... within a year we will have more answers... 95% or perhaps more are following protocols...there have been far more violators in the age groups 25 - 54... if you didn’t see that in this metro area several weeks ago then you have to be naive or oblivious... stay safe and well...seniors should wear masks or scarves simply to protect themselves from the knucklehead crowd.
Young kids are knuckle heads, but you expect that to some level from younger people. The old people? I wouldn't expect it as much, especially when they are in the most vulnerable group.
 
OK. Let's try this.

Just because the virus originated in bats and wasn't created in a lab does not preclude it being used for research in Wuhan's lab.

In fact I would be shocked if there are not samples of every coronavirus ever discovered in China in that lab being used for research.

you pointed out what i wanted to.
based on what i've read, the suspicion on the ccp is not the origin, it is the potential mishandling of the virus at the lab and letting it out to the world accidentally. and trying to cover it up. the ccp pointed to the wuhan market. it has been reported multiple times that the bats were not sold there. at this point, i don't think anyone believes anything from the ccp.
 
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I certainly understand the concern that this virus came from a Chinese lab. The Chinese government seems to have been secretive and dishonest about this virus, from trying to hide its existence at first, to providing apparently underreported case and death data. It is easy to assume that everything out of China is a lie.

But that doesn't mean this virus was developed in a lab. The simplest explanation is this virus developed naturally from another animal.
 
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In my store I have seen a ton of 70+ yr olds with no face coverings. That has changed a fair amount in recent days, but the idea that they "don't want scarf's around their faces"? Yeah, me neither.
Agreed , sadly many seniors live now in daily fear more so than a 20-40 year old... the death rate is dramatically increased in those over 60 as documented... too many are not in great shape which in itself can escalate the virus infection... on the other side there are many who have done what we are told is the right thing ...wear a mask or scarf...the supposed experts gave us a conflicted view as whether to wear one or not at the onset in this country... countries such as Japan and China have worn masks for many years... China with their pollution and dismal air quality is one reason... Japanese when traveling are almost always wearing a mask ... especially the over 40 crowd ...we all should try to do the mask routine until a proven vaccine is mass produced and distributed to the population .
 
SIAP. https://www.nature.com/articles/nm.3985.pdf

Published in November, 2015. "A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence"

work done down the road at UNC. The base sequence may have been found in bats, but these guys made one up based on that sequence in 2015.

Please look at researchers at top of article. Note Xing-Yi Ge

ROLES Formal analysis, Resources

AFFILIATION CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases of Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China


BS this virus just showed up in infected bats at the Wuhan market.
 
Agreed , sadly many seniors live now in daily fear more so than a 20-40 year old... the death rate is dramatically increased in those over 60 as documented... too many are not in great shape which in itself can escalate the virus infection... on the other side there are many who have done what we are told is the right thing ...wear a mask or scarf...the supposed experts gave us a conflicted view as whether to wear one or not at the onset in this country... countries such as Japan and China have worn masks for many years... China with their pollution and dismal air quality is one reason... Japanese when traveling are almost always wearing a mask ... especially the over 40 crowd ...we all should try to do the mask routine until a proven vaccine is mass produced and distributed to the population .
Agree 110%.
 
Agreed , sadly many seniors live now in daily fear more so than a 20-40 year old... the death rate is dramatically increased in those over 60 as documented... too many are not in great shape which in itself can escalate the virus infection... on the other side there are many who have done what we are told is the right thing ...wear a mask or scarf...the supposed experts gave us a conflicted view as whether to wear one or not at the onset in this country... countries such as Japan and China have worn masks for many years... China with their pollution and dismal air quality is one reason... Japanese when traveling are almost always wearing a mask ... especially the over 40 crowd ...we all should try to do the mask routine until a proven vaccine is mass produced and distributed to the population .
I think this might be younger folk projecting feelings onto older folks.

The older people I'm seeing, are not overly concerned by this. Otherwise they wouldn't be out, let alone out without masks.
 
Taiwan: 380 cases and 5 deaths. And they've been dealing with this since the beginning of January. Yet the WHO is continually quarreling with them and won't work with them.
 
Summary of today's US/NY/NJ data and some Cuomo presser comments. Since both NY and NJ appear to have reached the “peak plateau” in new cases, with some decline even looking like it’s occurring, I decided to reduce the volume of text and bullets on these notes, since we’re no longer at much risk of overwhelming our hospitals in NY/NJ and don’t need to dissect everything as closely. This should also save me some time. I also wanted to make these daily updates include a bit more on the situation in the World, the US and NJ, not just NY; hence the new graphics included. Feedback welcome...
  • 4/5: NY now has 340K tests, reaching the greatest testing per capita rate (17K tests per 1MM population) of any major country (only countries like Switzerland, Iceland and Norway have more)
  • The Earth hit 1.4MM cases on 4/6 with 400K positive cases in the US, although the daily new case rate in the US appears to have leveled off.
  • NY/NYC/NJ: new cases have peaked and plateaued and appear to be starting to decline.
  • US deaths continue to climb, hitting 1941 on 4/6, and NY deaths per day are still climbing a bit with 731 yesterday, up from 599 yesterday; NJ deaths jumpe from <100/day to 220 yesterday. Even with new cases leveling off or even declining, deaths would be expected to keep climbing for a few more days before leveling off, since deaths lag cases.
  • Total number of hospitalized in NY is leveling off and is expcted to peak around 20-25K in the next few days.
  • The daily number of ICU admissions has dropped the past few days, which is great news and will hopefully mean NY is ok with the number of ventilators they have.
  • While NY/NJ are doing better, plenty of states are still having cases rising fairly quickly.
  • Cuomo talked a lot about planning for how we might start returning slowly to “normal” once we (hopefully) decline to a much lower level of infections in the next couple of weeks. He said he’s working on regional plan with NJ and CT with a focus on one of the main things I had hoped to see: ensuring rapid viral testing to instantly know when there's a flare-up and antibody testing to see who can safely go back to work/life. Hopefully, he’ll add to that putting much better contact tracing/quarantining systems in place, so we can better prevent spread, especially from asymptomatic/infected contacts.
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Summary of key US/NY/NJ data through 4/8 and some comments from Cuomo’s 4/9 presser; several graphics are below.
  • The Earth hit 1.6MM positive cases on 4/8 with 403K cases in the US, 160K in NY and 51K in NJ
  • Both NY and NJ have reached the “peak plateau” in new cases, with some decline even looking like it’s occurring; the US appears to have reached a peak plateau also (see graphics)
  • NY now has done about 20,000 tests per 1MM in population, which is more than almost any other country; NJ is at 11,000 tests per 1MM and the US is at 7000 tests per 1MM, both of which are middle-of-the-pack.
  • US deaths continue to climb, hitting 1950 on 4/7, but dropping to 1450 on 4/8 (likely an accounting issue and not a trend downward) and NY deaths per day are still climbing a bit with 799 on 4/8 vs. 779 on 4/7, while NJ deaths were at 272 on 4/7 and dropped to 196 on 4/8 (probably not significant. Since we’ve now been on the new case plateau in NY/NJ for nearly a week, deaths will hopefully start to plateau in the next couple of days and maybe a few days later for the US.
  • 7067 total deaths in NY. 2753 NY deaths from 911. He had no words for how horrific this has been.
  • IMO, Cuomo does a superb job showing empathy for others, appreciation for everyone’s efforts, visioin for what needs to be done in the future and toughness for those who need it.
  • Total number of 18K hospitalized in NY has almost completely leveled off with the net new hospitalizations (~200) being the lowest they’ve been in almost 3 weeks.
  • This means NY is about at its peak and the peak should be in the 20-25K range. Cuomo showed the various model projections (see graphic) from the end of March for total hospitalizations and they ranged from about 50K to 135K, which is why NY was so aggressive in increasing their bed capacity from about 50K to 90K, which was accomplished. The high likelihood that this excess capacity won’t be needed is because the aggressive testing, quarantining and social distancing worked and continue to work. These need to continue.
  • Similar outcomes for ventilators and PPE, although NY almost ran out of those many times due to the demand and the logistical challenge of stocking and staffing so many hospitals.
  • While NY/NJ are doing better, plenty of states are having cases rising more quickly than NY/NJ.
  • Cuomo reiterated that there was a ton to do before returning slowly to “yellow” (the new normal) from our current “red” with “green” (the old normal likely being pretty far off still).


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In my store I have seen a ton of 70+ yr olds with no face coverings. That has changed a fair amount in recent days, but the idea that they "don't want scarf's around their faces"? Yeah, me neither.

I work in a Hardware store in a pretty affluent town.. 3 weeks ago.. maybe 10 people out of 200 wore a mask or some sort of face covering... Now... 10% of those coming in ( full age range) did NOT have any facial covering... And I'd say most of those started in the past few days....
 
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