COVID-19 Pandemic: Transmissions, Deaths, Treatments, Vaccines, Interventions and More...

[wisr01]

Not a clinical trial and yes it is anecdotal but still a worthwhile data point. For those who seem to be concerned, I did not read this on a far right wing looney site. I happen to be a Green Bay Packer fan and often read the JS online. Go Pack Go!

https://www.msn.com/en-us/health/me...-us-have-been-treated-with-plasma/ar-BB13hYs7

Hospitals and clinics across the country have given plasma from recovered COVID-19 patients to almost 2,600 of those still sick with the disease, and so far no major safety problems have arisen, according to experts who have been tracking the data.

"We have not seen any huge safety signals. The anecdotal evidence is overwhelmingly positive," said Michael J. Joyner, an anesthesiologist at the Mayo Clinic, who has been monitoring early results as well as setting up a clinical trial of the plasma treatment.

 

[bac2therac]

i wonder if he thinks the ny times is a far left loony site or are they the protectors of americans...rolls eyes

 

[RU#1fan]

To date, cov2 has now killed more Americans than the Vietnam war and you think people will not remember this pandemic?

This.
Nearly 60,000 Americans dead in under 7 weeks.
I think this will be in our minds for many years to come.

 

[ArminRU]

Sounds like Remdesivir works. No data available yet though...

https://www.statnews.com/2020/04/29...g-shows-patients-are-responding-to-treatment/

 

[richthedentist]

Also article on nj.com this morning about how Murphy reacted way to slow in New Jersey; I am not sure how to link the article. Also everyone thinks Cuomo is great but he reacted way to slow in New York also

 

[wisr01]

Also article on nj.com this morning about how Murphy reacted way to slow in New Jersey; I am not sure how to link the article. Also everyone thinks Cuomo is great but he reacted way to slow in New York also

https://www.nj.com/coronavirus/2020...gov-murphy-wait-too-long-to-shut-down-nj.html

 

[Upstream]

Sounds like Remdesivir works. No data available yet though...

https://www.statnews.com/2020/04/29...g-shows-patients-are-responding-to-treatment/

From the article, it looks like the study shows that Remdesivir works, but the data has not been released yet to show how much it works. But certainly the preliminary results show that at least some patients will see some improvement with Remdesivir, versus not taking Remdesivir.

Also the article references a second study, comparing treatment with Remdesivir for 5 days vs 10 days (but no non-Remdesivir arm in the study). This study showed that there is no difference between the 5 day and 10 day treatment. This suggests that stocks of Remdesivir can be used to treat twice as many patients, as they would only need 5 days of treatment, instead of 10.

Note that Remdesivir needs to be administered intravenously, so only patients sick enough to be hospitalized would be treated. I'm still hoping for another treatment that could help reduce hospitalization altogether.

But an array of treatments for those hospitalize, such as Remdesivir, monoclonal antibodies, and convalescent plasma (or synthetic antibodies), can at least help reduce the mortality rate of those hospitalized and get patients discharged faster.

 

[RU2055]

SIAP ......... but here's a list of places where you can get antibody testing .........

https://www.nj.com/coronavirus/2020/04/where-can-i-get-an-antibody-test-in-new-jersey.html

 

[richthedentist]

https://www.nj.com/coronavirus/2020...gov-murphy-wait-too-long-to-shut-down-nj.html

Thanks do you agree with the article ?

 

[wisr01]

Thanks do you agree with the article ?

How could anyone not agree? The doubling time at that moment was 3 days. If we had acted 1 week earlier we would likely had on 80,000 less cases and nearly 5000 less deaths. Two weeks earlier and we would have a few thousand cases and maybe a few hundred deaths.

 

[ArminRU]

From the article, it looks like the study shows that Remdesivir works, but the data has not been released yet to show how much it works. But certainly the preliminary results show that at least some patients will see some improvement with Remdesivir, versus not taking Remdesivir.

Also the article references a second study, comparing treatment with Remdesivir for 5 days vs 10 days (but no non-Remdesivir arm in the study). This study showed that there is no difference between the 5 day and 10 day treatment. This suggests that stocks of Remdesivir can be used to treat twice as many patients, as they would only need 5 days of treatment, instead of 10.

Note that Remdesivir needs to be administered intravenously, so only patients sick enough to be hospitalized would be treated. I'm still hoping for another treatment that could help reduce hospitalization altogether.

But an array of treatments for those hospitalize, such as Remdesivir, monoclonal antibodies, and convalescent plasma (or synthetic antibodies), can at least help reduce the mortality rate of those hospitalized and get patients discharged faster.

Yeah the double blinded test with the NIAID is the only one that really matters....so hopefully that data is release soon. The study that Gilead did is hard to quantify without a control arm, or at least stats of patients who were treated with “standard care”. They say 62% of patients treated earlier were discharged within 14 days.....but, is that good???

 

[RU848789]

Lancet: Remedesivir clinical trial shows no efficacy in patients with severe COVID-19, unfortunately, although most experts think anti-virals will be more effective earlier in the course of treatment.

https://www.thelancet.com/journals/...avirus20&utm_source=twitter&utm_medium=social

Findings
Between Feb 6, 2020, and March 12, 2020, 237 patients were enrolled and randomly assigned to a treatment group (158 to remdesivir and 79 to placebo); one patient in the placebo group who withdrew after randomisation was not included in the ITT population. Remdesivir use was not associated with a difference in time to clinical improvement (hazard ratio 1·23 [95% CI 0·87–1·75]). Although not statistically significant, patients receiving remdesivir had a numerically faster time to clinical improvement than those receiving placebo among patients with symptom duration of 10 days or less (hazard ratio 1·52 [0·95–2·43]). Adverse events were reported in 102 (66%) of 155 remdesivir recipients versus 50 (64%) of 78 placebo recipients. Remdesivir was stopped early because of adverse events in 18 (12%) patients versus four (5%) patients who stopped placebo early.

Interpretation
In this study of adult patients admitted to hospital for severe COVID-19, remdesivir was not associated with statistically significant clinical benefits. However, the numerical reduction in time to clinical improvement in those treated earlier requires confirmation in larger studies.

 

[ArminRU]

Lancet: Remedesivir clinical trial shows no efficacy in patients with severe COVID-19, unfortunately, although most experts think anti-virals will be more effective earlier in the course of treatment.

https://www.thelancet.com/journals/...avirus20&utm_source=twitter&utm_medium=social

Findings
Between Feb 6, 2020, and March 12, 2020, 237 patients were enrolled and randomly assigned to a treatment group (158 to remdesivir and 79 to placebo); one patient in the placebo group who withdrew after randomisation was not included in the ITT population. Remdesivir use was not associated with a difference in time to clinical improvement (hazard ratio 1·23 [95% CI 0·87–1·75]). Although not statistically significant, patients receiving remdesivir had a numerically faster time to clinical improvement than those receiving placebo among patients with symptom duration of 10 days or less (hazard ratio 1·52 [0·95–2·43]). Adverse events were reported in 102 (66%) of 155 remdesivir recipients versus 50 (64%) of 78 placebo recipients. Remdesivir was stopped early because of adverse events in 18 (12%) patients versus four (5%) patients who stopped placebo early.

Interpretation
In this study of adult patients admitted to hospital for severe COVID-19, remdesivir was not associated with statistically significant clinical benefits. However, the numerical reduction in time to clinical improvement in those treated earlier requires confirmation in larger studies.

I think that’s the Chinese one wasn’t done properly.

 

[Upstream]

Thanks do you agree with the article ?

Obviously if Murphy shut down the state earlier, there would have been less virus spread. But with limited testing, the virus was probably already widespread with significant community spread by the time the first case was confirmed in NJ.

If you look at the growth in NJ and NY, compared to Calif and Washington, you can see the infection growth was much faster in NY and NJ, indicating that there was already significant infection rates and community spread.

(Data from Hopkins Coronavirus Dashboard)
State / 1st case reported / 10th case reported / 50th case reported / # Days from 10th case to Stay-at-home order
NJ / Mar-5 / Mar 10 / Mar 14 / 11
NY / Mar 2 / Mar 4 / Mar 7 / 18
Calif / Jan 26 / Feb 21 / Mar 5 / 27
Wash / Jan 22 / Mar 1 / Mar 5 / 22

Due to the restrictive nature of the CDC testing requirements, there was more testing done earlier on the west coast than the northeast. By the time the first cases were discovered in the northeast, there was likely significant community spread.

The governors in the Northeast would have had to issue stay-at-home orders prior to the first cases being confirmed in their states in order to hit the timelines of Western states.

So yes, if stay-at-home orders were issued earlier in NJ and NY, then the outbreak could have been contained better. And if the CDC allowed testing earlier in NJ and NY, then the first cases would have been identified earlier, providing the data to support stay-at-home orders.

 

[RU848789]

Not a clinical trial and yes it is anecdotal but still a worthwhile data point. For those who seem to be concerned, I did not read this on a far right wing looney site. I happen to be a Green Bay Packer fan and often read the JS online. Go Pack Go!

https://www.msn.com/en-us/health/me...-us-have-been-treated-with-plasma/ar-BB13hYs7

Hospitals and clinics across the country have given plasma from recovered COVID-19 patients to almost 2,600 of those still sick with the disease, and so far no major safety problems have arisen, according to experts who have been tracking the data.

"We have not seen any huge safety signals. The anecdotal evidence is overwhelmingly positive," said Michael J. Joyner, an anesthesiologist at the Mayo Clinic, who has been monitoring early results as well as setting up a clinical trial of the plasma treatment.

Great to hear continued positive anecdotal evidence especially on safety, thanks. Dying to see the results from the controlled clinical trials (supposedly soon). FDA/Mayo Clinic Expanded Access Program has a new website up (first link), which shows how many patients have been treated with plasma (over 3000 now) under this program being administered by the Mayo Clinic. It's also not quite clear how the data from expanded access program will be used (retrospective comparisons to "similar" patients who don't get plasma?).

Nice story in the Times link of a Florida doctor who contracted COVID on 3/31 and was in pretty bad shape, so his family beat the bushes to find a plasma donor and did and the doc looks to be on the road to recovery (still in the hospital but doing much better).

https://www.uscovidplasma.org/

https://www.nytimes.com/2020/04/29/us/coronavirus-plasma-donors.html

 

[RU848789]

I think that’s the Chinese one wasn’t done properly.

It was halted early due to enrollment issues, but there's no indication that what was done was done improperly or else I doubt the Lancet would've published it.

 

[wisr01]

http://investors.gilead.com/news-re...sults-phase-3-trial-investigational-antiviral

In an exploratory analysis, patients in the study who received remdesivir within 10 days of symptom onset had improved outcomes compared with those treated after more than 10 days of symptoms. Pooling data across treatment arms, by Day 14, 62 percent of patients treated early were able to be discharged from the hospital, compared with 49 percent of patients who were treated late.


__________________________________________________
I would bet treating in the first 5 days of onset would be even better but not easy due to mode of treatment.

 

[RU-05]

How could anyone not agree? The doubling time at that moment was 3 days. If we had acted 1 week earlier we would likely had on 80,000 less cases and nearly 5000 less deaths. Two weeks earlier and we would have a few thousand cases and maybe a few hundred deaths.

I don't argue the science, but I'm not sure how compliant US citizens would have been without the massive outbreak in NYC.

There are still some who downplay the need for a shutdown even in the face of 50K deaths in a month.

 

[ArminRU]

It was halted early due to enrollment issues, but there's no indication that what was done was done improperly or else I doubt the Lancet would've published it.

Eh, I’ll wait for the NIAID results.

 

[RUBigFrank]

Dr. Anthony Fauci says data from remdesivir coronavirus drug trial shows ‘quite good news’

https://www.cnbc.com/2020/04/29/dr-...navirus-drug-trial-shows-quite-good-news.html

seems the Chinese have the WHO Director in their back pocket.

 

[RU-05]

Dr. Anthony Fauci says data from remdesivir coronavirus drug trial shows ‘quite good news’

https://www.cnbc.com/2020/04/29/dr-...navirus-drug-trial-shows-quite-good-news.html

seems the Chinese have the WHO Director in their back pocket.

I can forgive the WHO for being duped at the onset of this thing. They were the first, but not the last in a long line who bought into China's cover up.

But if they didn't learn their lesson from that, then they are cementing the idea that they also can not be trusted.

 

[RU848789]

Eh, I’ll wait for the NIAID results.

Fauci happy with them - looking at least decent, which is great news...

During an appearance alongside President Trump in the Oval Office, Anthony Fauci, the director of NIAID, said the data are a “very important proof of concept” and that there was reason for optimism, but cautioned the data were not a “knockout.”

https://www.statnews.com/2020/04/29...g-shows-patients-are-responding-to-treatment/

 

[RU2055]

Lancet: Remedesivir clinical trial shows no efficacy in patients with severe COVID-19, unfortunately, although most experts think anti-virals will be more effective earlier in the course of treatment.

https://www.thelancet.com/journals/...avirus20&utm_source=twitter&utm_medium=social

Findings
Between Feb 6, 2020, and March 12, 2020, 237 patients were enrolled and randomly assigned to a treatment group (158 to remdesivir and 79 to placebo); one patient in the placebo group who withdrew after randomisation was not included in the ITT population. Remdesivir use was not associated with a difference in time to clinical improvement (hazard ratio 1·23 [95% CI 0·87–1·75]). Although not statistically significant, patients receiving remdesivir had a numerically faster time to clinical improvement than those receiving placebo among patients with symptom duration of 10 days or less (hazard ratio 1·52 [0·95–2·43]). Adverse events were reported in 102 (66%) of 155 remdesivir recipients versus 50 (64%) of 78 placebo recipients. Remdesivir was stopped early because of adverse events in 18 (12%) patients versus four (5%) patients who stopped placebo early.

Interpretation
In this study of adult patients admitted to hospital for severe COVID-19, remdesivir was not associated with statistically significant clinical benefits. However, the numerical reduction in time to clinical improvement in those treated earlier requires confirmation in larger studies.

"No specific antiviral drug has been proven effective for treatment of patients with severe coronavirus disease 2019 (COVID-19)"

Well, no duh!!! For covid-19 patients in severe state, it ain't the virus any more doing the damage. That's what IL-6 antagonists are for and perhaps plasma.

Anyone (not you numbers, but pubs like the Lancet) pushing the narrative that the anti-virals don't work for severe patients have an ulterior motive. And it's not for the good of humanity.

Disease progression will require different therapies - not sure why many can't understand this.

 

[RU2055]

Dr. Anthony Fauci says data from remdesivir coronavirus drug trial shows ‘quite good news’

https://www.cnbc.com/2020/04/29/dr-...navirus-drug-trial-shows-quite-good-news.html

seems the Chinese have the WHO Director in their back pocket.

Won't shock me one bit if China is already mass producing remedesivir knock offs They're know for doing crap like this.

https://www.wsj.com/articles/SB10001424052702303918204577448221514110882

 

[RU-05]

Won't shock me one bit if China is already mass producing remedesivir knock offs They're know for doing crap like this.

https://www.wsj.com/articles/SB10001424052702303918204577448221514110882

And we Americans will clamor to buy them because they are cheaper.

Or have we finally learned a lesson?

 

[wisr01]

http://covexit.com/professor-raoult...ents-and-media-delirium/#.Xqm4EpBaU4Q.twitter



Below is twitter of guy running HCQ trial in MN. He mentions the flaw in the Brazil study as they dosed at levels way too high versus the known safety profile.
https://twitter.com/boulware_dr

Here is a tweet he made recently:

Would also add that we have now had 3 interim safety analyses without any safety concerns observed to date in >1000 participants.

 

[ArminRU]

Fauci happy with them - looking at least decent, which is great news...

During an appearance alongside President Trump in the Oval Office, Anthony Fauci, the director of NIAID, said the data are a “very important proof of concept” and that there was reason for optimism, but cautioned the data were not a “knockout.”

https://www.statnews.com/2020/04/29...g-shows-patients-are-responding-to-treatment/

Well that’s a good sign. It’s definitely not a tamiflu-like solution, but hopefully it helps to decrease the mortality rate.

 

[RUJohnny]

Murphy's Reopening Committee. Zero small business representation. No chamber of commerce. no non-union labor. No agriculture. It's a bureaucrat paradise.

Dr. Shirley M. Tilghman (Co-Chair) – Professor of Molecular Biology & Public Policy and President Emeritus of Princeton University.
• Kenneth Frazier (Co-Chair) – Chairman and Chief Executive Officer of Merck
• Dr. Ben Bernanke – Distinguished Fellow in Residence at the Brookings Institute and former Chairman of the Board of Governors of the Federal Reserve
• Dr. Richard Besser – President and CEO of the Robert Wood Johnson Foundation and former Acting Director for the CDC
• Evie Colbert – Founding Board Member and President of the Board of Montclair Film and Vice President of Spartina Productions.
• Tony Coscia – Chairman of the Board of Directors of the National Railroad Passenger Corporation at Amtrak, Partner and Executive
• Committee member of Windels Marx LLP law firm and Chairman of SUEZ North America.
• Jessica Gonzalez – Founder and Chief Executive Officer of InCharged, VendX, and Lux-UVC.
• Dr. Jonathan Holloway – Incoming President of Rutgers University and former Provost of Northwestern University
• Lisa P. Jackson – Vice President of Environment, Policy and Social Initiatives at Apple and former Administrator of the EPA.
• Jeh Johnson – Former U.S. Secretary of the U.S. Department of Homeland Security and Partner at the law firm Paul Weiss LLP.
• Charles Lowrey – Chairman and Chief Executive Officer of Prudential.
• Denise Morrison – Founder of Denise Morrison & Associates, LLC and a Senior Advisor for PSP Partners. Former President and Chief Executive Officer of the Campbell Soup Company.
• Dr. William Rodgers – Professor of Public Policy and Chief Economist at the Heldrich Center at Rutgers. Former Chief Economist at the U.S. Department of Labor
• Neera Tanden – President and CEO of American Progress and the CEO of the Center for American Progress Action Fund.
• Reverend Dr. Regena Thomas - Director of the Human Rights and Community Relations Department of AFT Union and former New Jersey Secretary of State.
• Richard Trumka – President of the AFL-CIO.

Five members of the Murphy administration will sit as ex officio members:
• Lt. Gov. Sheila Oliver
• NJ Dept. of Health Commissioner Judith Persichilli
• Chief of Staff George Helmy
• Chief Counsel Matt Platkin
• Chief Policy Advisor Kathleen Frangione

 

[RU848789]

"No specific antiviral drug has been proven effective for treatment of patients with severe coronavirus disease 2019 (COVID-19)"

Well, no duh!!! For covid-19 patients in severe state, it ain't the virus any more doing the damage. That's what IL-6 antagonists are for and perhaps plasma.

Anyone (not you numbers, but pubs like the Lancet) pushing the narrative that the anti-virals don't work for severe patients have an ulterior motive. And it's not for the good of humanity.

Disease progression will require different therapies - not sure why many can't understand this.

It's not "pushing a narrative" to publish a clinical trial that showed remdesivir was ineffective in severe COVID patients. It was also a randomized, double-blind, placebo controlled study, so it's not "bad data." One can certainly debate the merits of trying antivirals on severe patients, but then again, at the time in China they were trying everything.

 

[wisr01]

https://www.businessinsider.com/coronavirus-pfizer-biontech-vaccine-fall-2020-4

A coronavirus vaccine being developed by Pfizer and the German company BioNTech could be ready for emergency use by this fall, Pfizer's CEO told The Wall Street Journal on Tuesday.

The two companies said in a statement on Wednesday that they began giving the experimental shot to 12 people in Germany on Thursday. The data from this trial is expected "as early as June this year," a BioNTech representative told Business Insider.

 

[RU848789]

Lots of disagreement on this topic,as I know you know, but others might not. The opinion of most infectious disease experts, like Fauci, is that "reinfection" is much more likely a function of testing accuracy of the viral PCR test, which is not particularly accurate (~30+% false negatives and some false positives). Scientifically, it simply makes no sense for a person who recovers from a viral infection to not then have the antibodies to be immune from reinfection, at least for some time, except for people with immunological issues, as was reported this past weekend in my post below - this was based on the best antibody test out there, now. Since this is a new virus, there are no guarantees that reinfection isn't possible, but it's not the way to bet. From the article you linked, below...

The Korea Centers for Disease Control and Prevention (KCDC) said in a statement a formal investigation was underway looking into dozens of patients that reportedly tested positive for the disease for a second time.

“While we are putting more weight on reactivation as the possible cause, we are conducting a comprehensive study on this,” KCDC Director-General Jeong Eun-kyeong said, according to Bloomberg. “There have been many cases when a patient during treatment will test negative one day and positive another.”

Similar reports have come out of China, where the virus emerged late last year, and Japan in February reported a woman tested positive for the coronavirus a second time.

But some researchers say reinfection is an unlikely explanation for patients who test positive twice, and note the possibility that testing errors, and releasing patients from hospitals too early, are more likely to be the cause of patients who retest positive.

“If you get an infection, your immune system is revved up against that virus,” Keiji Fukuda, director of Hong Kong University’s School of Public Health, told The Los Angeles Times in March. “To get reinfected again when you’re in that situation would be quite unusual unless your immune system was not functioning right.”
.

Interesting report from South Korea - looks like the reports of viral reinfection were simply artifacts of testing as expected (very few virologists thought reinfection would be possible). However, it would be nice to see their data or a paper on this...

SEOUL, April 29 (Yonhap) -- South Korean health experts said Wednesday that recovered coronavirus patients may have tested positive again due to traces of virus fragments that have been inactivated.

As of Tuesday, a total of 277 people who recovered from COVID-19 have retested positive here, according to the Korea Centers for Disease Control and Prevention (KCDC).

The country's central clinical committee for emerging disease control said there was no live virus present in such cases, positively refuting theories like the virus being reactivated or reinfection.

https://en.yna.co.kr/view/AEN20200429007051320

 

[Proud NJ Sports Fan]

Another person in their 30s dies from CV

This is getting scarier


https://www.nj.com/coronavirus/2020...mplications-of-coronavirus-officials-say.html

 

[RUJohnny]

Another person in their 30s dies from CV

This is getting scarier


https://www.nj.com/coronavirus/2020...mplications-of-coronavirus-officials-say.html

Why? Are there more people under 45 dying now per capita than there were two weeks ago? I doubt it.

 

[Proud NJ Sports Fan]

Why? Are there more people under 45 dying now per capita than there were two weeks ago? I doubt it.

Yes

 

[ArminRU]

Summary from the NIAID trial for Remdesivir.

“Preliminary results indicate that patients who received remdesivir had a 31% faster time to recovery than those who received placebo (p<0.001). Specifically, the median time to recovery was 11 days for patients treated with remdesivir compared with 15 days for those who received placebo. Results also suggested a survival benefit, with a mortality rate of 8.0% for the group receiving remdesivir versus 11.6% for the placebo group (p=0.059).”

http://www.niaid.nih.gov/news-event...esivir-accelerates-recovery-advanced-covid-19

 

[satnom]

We have short memories and that is a good thing . The world will be very different in 2040 . Millions of people will be dead that lived through this. The more advanced we become the less we dwell on the negative things. Do you believe in 20 years the Trade Center disaster will be met with the same vigor as it did years 1-5-10-15...it gets less and less as years pass. There will be other issues which will take over the news.

WTF is wrong with you ? Nobody said it wouldn’t be in the annals of history but it will be over and old history. You are another with a big mouth who could not wait to interject your attack . I don’t know how old you are so you may or may not see whether it gets the same attention as it does now. If I make 20 more I’ll be in my 90’s and won’t give a shit what you think. You are highly educated but arrogant and self opinionated . Since it is 2020 not 20 years in the future neither you nor I can actually know how the world will view this pandemic... we have had numerous pandemics throughout history. What makes this pandemic so bad ? The daily overblown media coverage which is no better than your favorite Trump. The issue you had was it didn’t fit with Mr. Merck’s opinion on what are the most horrific disasters in the history of man. Vietnam was not a war. It was a police action not a war. You probably protested while others actually where sent by the government to fight in a senseless conflict. Most under age 35 basically know very little about and probably don’t care about the Great Depression.Don’t patronize me fool.

Why do you post such drivel? Between 1965-74 upwards of 1.7MM people died. An additional 1.3MM people were killed in the Southeast Asia conflict from 1955-64 not even counting the 810k that died post US withdrawal from 1975-84. For total death toll of over 3million people that were killed during this “police action”. Calling you an idiot would be an insult to certified idiots.

You must live in an alternative world with what you post here at times. I pray that your offshoot posts are not of your control.

GO RU

 

[RU#1fan]

Also article on nj.com this morning about how Murphy reacted way to slow in New Jersey; I am not sure how to link the article. Also everyone thinks Cuomo is great but he reacted way to slow in New York also

The President had first hand knowledge of the impending Coronavirus and the mass casualties it would cause back in January and he did nothing. Fake News... it will disappear overnight. lmao

 

[RUJohnny]

Yes

source?

 

[goru7]

From the article, it looks like the study shows that Remdesivir works, but the data has not been released yet to show how much it works. But certainly the preliminary results show that at least some patients will see some improvement with Remdesivir, versus not taking Remdesivir.

Also the article references a second study, comparing treatment with Remdesivir for 5 days vs 10 days (but no non-Remdesivir arm in the study). This study showed that there is no difference between the 5 day and 10 day treatment. This suggests that stocks of Remdesivir can be used to treat twice as many patients, as they would only need 5 days of treatment, instead of 10.

Note that Remdesivir needs to be administered intravenously, so only patients sick enough to be hospitalized would be treated. I'm still hoping for another treatment that could help reduce hospitalization altogether.

But an array of treatments for those hospitalize, such as Remdesivir, monoclonal antibodies, and convalescent plasma (or synthetic antibodies), can at least help reduce the mortality rate of those hospitalized and get patients discharged faster.

Still only from small sample size from the front line, but Leronlimab , a monoclonal antibody has shown to both to reduce viral load but stop the cytokines storm with little to no side effects. The FDA expedited trials will have results on May 12. Leronlimab is given by injection once a week as compared to Remdesiver given by IV. So it should be given at home . The next 2 -4 weeks , will likely see a lot of therapeutics being touted as a treatment for Covid but in the end Leronlimab seems like the most promising.

 

[RUBOB72]

Why do you post such drivel? Between 1965-74 upwards of 1.7MM people died. An additional 1.3MM people were killed in the Southeast Asia conflict from 1955-64 not even counting the 810k that died post US withdrawal from 1975-84. For total death toll of over 3million people that were killed during this “police action”. Calling you an idiot would be an insult to certified idiots.

You must live in an alternative world with what you post here at times. I pray that your offshoot posts are not of your control.

GO RU