This is their wave 1. It's a big country, waves hit states at different times.
COVID-19 Pandemic: Transmissions, Deaths, Treatments, Vaccines, Interventions and More...
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SIAP, but we got some preliminary phase I and II data on SinoPharm's (China) deactivated coronavirus vaccine, a traditional old-school approach which has a high likelihood of working, but is difficult to scale to hundreds of millions of doses (since one has to "grow" a huge amount of SARS-CoV-2 virus and then deactivate it and then concentrate it to a much smaller volume for use). Not a full data set, but enough to see that side effects were a bit lower than other vaccines, although the response level of neutralizing antibodies was similar to that of most of the other vaccines (but hopefully unacceptable, although we won't know for sure, obviously, until we see phase III results; no T-cell response data, however). This vaccine will also require 2 shots. Much more detailed analysis today in Derek Lowe's blog, linked/excerpted below.
https://blogs.sciencemag.org/pipeline/archives/2020/08/17/sinopharms-inactivated-coronavirus-vaccine
So this is a rather preliminary report (as the authors themselves note), but it’s the first one we have on an inactivated vaccine. Like all of the others so far except the J&J Ad26 one, this candidate will also need a booster shot. The small and mild adverse-event reactions here are really the main thing that stands out – if you’re a glass half full person, then you can be glad about that, but if you’re a glass-half-empty one, you might wonder about the overall robustness of the immune response. We’re going to need more data to make any calls about that, and (just as with every other vaccine under development!) the real numbers we’re waiting on for efficacy. How many people will this (or any) vaccine protect, and how well? Stay tuned.
https://blogs.sciencemag.org/pipeline/archives/2020/08/17/sinopharms-inactivated-coronavirus-vaccine
So this is a rather preliminary report (as the authors themselves note), but it’s the first one we have on an inactivated vaccine. Like all of the others so far except the J&J Ad26 one, this candidate will also need a booster shot. The small and mild adverse-event reactions here are really the main thing that stands out – if you’re a glass half full person, then you can be glad about that, but if you’re a glass-half-empty one, you might wonder about the overall robustness of the immune response. We’re going to need more data to make any calls about that, and (just as with every other vaccine under development!) the real numbers we’re waiting on for efficacy. How many people will this (or any) vaccine protect, and how well? Stay tuned.
If Florida has a Dem gov, numbers would be typing novels on how great a job they were doing
um thats not science you are just generalizing your own thoughts
i guess Cuomo was so lucky he ran out of seniors to kill
NO one cares what your anti-weed advocate who has no science or medical training says.
So basically masks work exactly as you've been told for five months.
Surgical masks and other coverings do NOT protect the wearer and will NOT be effective blocking outside particles. They are to protect the public from the wearer(s) from spewing their particles into the air.
2. N95 masks do and always have protected the wearer from 95 percent of airborne particles. It's in the name, not hard to remember. Problem is they were not readily available for those that needed them the most, let alone the general pop.
You keep saying you're just asking questions, but how many times do you need the same answers??
You really don't understand infectious diseases. There was certainly a wave 1, but it was muted and it was muted because they were seeded with far less early cases than the NE US in Feb/March (in retrospect, since we had little to no testing early on to know this), but they still shut down at a similar time, meaning their slow start meant a slow, controlled low-level wave 1. Same for most other states that had muted first waves.
Interesting paper, but I think research of filtration of actual viruses/bacteria of similar particle sizes as SARS-CoV-2, as per the post/paper below are a better evaluation than making an "artificial" aerosol using particulates and assuming filtration is not affected by the biological/moisture component. And while it's useful to know that surgical masks might not work as well based on operator variability, I'd rather know the "true" filtration efficiency of the mask material, which is what the study below showed.
Surigical/cloth masks are clearly not as good as N95's but are capable of way better than the JAMA study if worn properly and one of the big keys to masks is that if both people in contact are wearing them, one gets to account for the effectiveness of both, i.e., if both have 60% efficiency, then the overall efficiency is 84% -0 not perfect, but way better than zero. Here's my post from 5/21 on mask material filtration.
https://rutgers.forums.rivals.com/t...entions-and-more.191275/page-125#post-4571736
People have asked about filtration effectiveness of various homemade and purchased masks for removing the ~0.1 micron virus particles; see the graphic below for measurements made with a 0.02 micron bacteria that is about 1/5 the size of the coronavirus in a 2013 paper that was looking at various masks in anticipation of the next flu pandemic (influenza virus is similar size to coronavirus).
The take home message is that, worn properly, surgical masks are quite effective (~90%) and effectiveness goes down with some of the homemade masks, but are all still >50%. Mask wearing of homemade masks, combined with social distancing is even better and can greatly reduce transmission rates as per previous posts.
Also, keep in mind that these filtration efficiencies are for aerosolized bacteria being coughed/breathed out by volunteers and not "true" virus-laden droplets in a cough (or sneeze - can't have people sneeze on command, though, so that wasn't tested), which would generally be significantly larger and more likely to be retained by the mask, i.e, the numbers in the table are likely worst case - for properly worn masks (poorly worn masks are not much good, as per the paper).
https://www.researchgate.net/public...Y62EkeFogLCUGD6T2p2UDKampUafTtBRYQPBKfx4Uw9IU
You / Twitter source left out context. When discussing the poor-performing mask referenced in the tweet, the paper says the elastic ear loops resulted in a poor fit that created visible gaps between the mask and the face; said this failure demonstrates the importance of a proper fitting mask.
Incredibly detailed and comprehensive survey of the history of infectious diseases and how that history informs modern pandemics, like our current one and what that might mean for future pandemics, by Drs. Morens and Fauci from NIAID, entitled Emerging Pandemic Diseases - How We Got To COVID-19. It's 76 pages long, so I only skimmed it and rather than trying to make any comments about it, I'm simply copying the Summary/Conclusions below. Dr. Fauci is simply a machine to be able to do his day job and co-author papers like this while putting in 16-hour days at the age of 79. Will try to find time to read through it later.
https://www.cell.com/action/showPdf?pii=S0092-8674(20)31012-6
Summary and Conclusions. SARS-CoV-2 is a deadly addition to the long list of microbial threats to the human species. It forces us to adapt, react, and reconsider the nature of our relationship to the natural world. Emerging and re-emerging infectious diseases are epiphenomena of human existence and our interactions with each other, and with nature. As human societies grow in size and complexity, we create an endless variety of opportunities for genetically unstable infectious agents to emerge into the unfilled ecologic niches we continue to create.
There is nothing new about this situation, except that we now live in a human-dominated world in which our increasingly extreme alterations of the environment induce increasingly extreme backlashes from nature. Science will surely bring us many life-saving drugs, vaccines, and diagnostics; however, there is no reason to think that these alone can overcome the threat of ever more frequent and deadly emergences of infectious diseases. Evidence suggests that SARS, MERS and COVID-19 are only the latest examples of a deadly barrage of coming coronavirus emergences.
The COVID-19 pandemic is yet another reminder, added to the rapidly-growing archive of historical reminders, that in a humandominated world, in which our human activities represent aggressive, damaging, and unbalanced interactions with nature, we will increasingly provoke new disease emergences. We remain at risk for the foreseeable future. COVID-19 is among the most vivid wake-up calls in over a century. It should force us to begin to think in earnest and collectively about living in more thoughtful and creative harmony with nature, even as we plan for nature’s inevitable, and always unexpected, surprises.
https://www.cell.com/action/showPdf?pii=S0092-8674(20)31012-6
Summary and Conclusions. SARS-CoV-2 is a deadly addition to the long list of microbial threats to the human species. It forces us to adapt, react, and reconsider the nature of our relationship to the natural world. Emerging and re-emerging infectious diseases are epiphenomena of human existence and our interactions with each other, and with nature. As human societies grow in size and complexity, we create an endless variety of opportunities for genetically unstable infectious agents to emerge into the unfilled ecologic niches we continue to create.
There is nothing new about this situation, except that we now live in a human-dominated world in which our increasingly extreme alterations of the environment induce increasingly extreme backlashes from nature. Science will surely bring us many life-saving drugs, vaccines, and diagnostics; however, there is no reason to think that these alone can overcome the threat of ever more frequent and deadly emergences of infectious diseases. Evidence suggests that SARS, MERS and COVID-19 are only the latest examples of a deadly barrage of coming coronavirus emergences.
The COVID-19 pandemic is yet another reminder, added to the rapidly-growing archive of historical reminders, that in a humandominated world, in which our human activities represent aggressive, damaging, and unbalanced interactions with nature, we will increasingly provoke new disease emergences. We remain at risk for the foreseeable future. COVID-19 is among the most vivid wake-up calls in over a century. It should force us to begin to think in earnest and collectively about living in more thoughtful and creative harmony with nature, even as we plan for nature’s inevitable, and always unexpected, surprises.
https://www.nytimes.com/2020/08/17/...html?action=click&module=News&pgtype=Homepage
Seems the same pattern is playing out in Italy also.
Seems the same pattern is playing out in Italy also.
This 65 year old gentleman suffered from an elevated BMI level as is clearly visible in the photo. It is sad he passed from covid19 but his daughter claiming he literally took the words as gospel and didn’t do some personal research also is what is his fault. To cherry pick out individuals who perhaps need to blame the other “ guy or gal “ for something unfortunate is exactly what has permeated our society over the past 40+ years. As an adult you have to use some sensibility especially with viral diseases ...
Yeh it seeded so deeply in NE US because NY/NYC ignored its chicomvirus infection models until SanFran sounded the alarm, and even then fumbled and bumbled for almost another week.
Interesting data about misconceptions
https://www.franklintempletonnordic.../on-my-mind-they-blinded-us-from-science.html
https://www.franklintempletonnordic.../on-my-mind-they-blinded-us-from-science.html
MN Governor Quietly Reverses Course on Hydroxychloroquine
This past week Minnesota became the second state to reject regulations that effectively ban the controversial drug hydroxychloroquine for use by COVID-19 patients.
https://www.realclearpolitics.com/a...ses_course_on_hydroxychloroquine__143978.html
This past week Minnesota became the second state to reject regulations that effectively ban the controversial drug hydroxychloroquine for use by COVID-19 patients.
https://www.realclearpolitics.com/a...ses_course_on_hydroxychloroquine__143978.html
Interesting that you go to Investment banks for science and medical information. Do you go to doctors for information on how to invest your money, plumbers about how to play baseball, and baseball players when you have a flood?
Here is a scary idea from a professor of medical ethics: Secretly drug the entire population so they will be more willing to follow social distancing and masking rules.
https://theconversation.com/moralit...rus-pandemic-according-to-one-ethicist-142601
https://theconversation.com/moralit...rus-pandemic-according-to-one-ethicist-142601
Pretty sure he just googles text of whatever his latest flip-flopped opinion is and finds garbage tweets and blogs to support it.
And that's why spinster cat ladies aren't running this country. Or anything more complex than litter box duty.
A lot of optimism swirling around in the last few days about immunity after you recover from CV. Everyone was assuming it, but we’re starting to see some proof of at least 3 months (likely more like numbers has been saying).
Same thing for people who may have some level of immunity due to cross-reactive antibodies from a previous coronavirus. From what I’ve been reading, this is slowly starting to become an accepted assumption. Still needs to be proven though.
These articles touch on a lot of the recent thinking.
https://www.cnn.com/2020/08/17/health/immunity-studies-optimism-covid-19/index.html
https://www.nature.com/articles/d41586-020-02400-7
All of this, especially how the body is reacting naturally to CV, is giving confidence on the prospect of a working vaccine. The thinking is since vaccines are causing a similar response compared to infected people, the same immunity will be true for vaccinated people.
Same thing for people who may have some level of immunity due to cross-reactive antibodies from a previous coronavirus. From what I’ve been reading, this is slowly starting to become an accepted assumption. Still needs to be proven though.
These articles touch on a lot of the recent thinking.
https://www.cnn.com/2020/08/17/health/immunity-studies-optimism-covid-19/index.html
https://www.nature.com/articles/d41586-020-02400-7
All of this, especially how the body is reacting naturally to CV, is giving confidence on the prospect of a working vaccine. The thinking is since vaccines are causing a similar response compared to infected people, the same immunity will be true for vaccinated people.
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Apparently over in Spain they're revolting against wearing masks:
Coronavirus: Hundreds gather in Madrid for anti-mask protest
Coronavirus: Hundreds gather in Madrid for anti-mask protest
During the Roaring Twenties,people who wanted to drink could still do so in "speakeasies" hidden away from sight.In these,the Boring Twenties,gym owners should move their equipment to abandoned factories to establish "lifteasies."
On Coast to Coast tonight,George Noory hosts "The Great Mask Debate."
On Coast to Coast tonight,George Noory hosts "The Great Mask Debate."
Or people can lift at home! Or just drive half an hour to PA or NY.
I don't blame you. I actually agree it seems like time to open up in some form.
But in the meantime, ya gotta just take charge, just like you did. Best thing anyone can do for himself right now. If things get shut down or canceled ...move on to whatever's closest and still available, preferably something not subject to the whims of government and business.
No way gyms don’t open in some for within the next month. Overdue imo.
Push up is a great exercise but don’t ignore the back!
I'm really interested in how they're going to go about it, not Murphy laying down the guidelines but more about how the gyms handling those guidelines, everyone is going to be itching to get back in there but how can they just open the doors and after capacity is reached (figure 25%) turn people away? That's going to be a bad scene so there has to be a system where you sign up for a certain hour and that's all you get.
I hate back exercises, could never put the effort into them unless its pull ups.
lol...he said weeks not months at the beginning of June..we are nearing 3 months since he said that...meanwhile all the neighboring states of governors opened their gyms by the end of June except for NY which will be open next week
Murphy knows exactly what he is doing and why
the good thing is that some people will not go..thats great. The diehards will be there which means the true people who are dedicated to working out. Better than clogging things up with wannabees and people who go through the motions
I anticipate signs up for time periods will occur
Yep, reserved gym times have to be the only way to manage it, and the Mon-Fri after-work crowd (incl. me) will have to be flexible. I don't know if it will be doable for my schedule....nobody better be dawdling and sitting on benches and machines playing with their damn phones! I'll give it a try, but have already started looking into serious at-home gym equipment. I've been using some old dumbbells but otherwise it's pretty much just pushups and sit-ups at home since the March shutdowns.
It might be the best thing if you're a lollygagger at the gym, just before the virus hit I started the practice of leaving my phone in my car because too many times I'd find myself preoccupied by it and not my workout and I was having my best workouts as a result as I was doing my reps one after the other instead of finding myself down a rabbit hole on my phone.
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