Article on CDC demographic breakdown of who is getting COVID.
https://www.cnn.com/2020/06/15/politics/cdc-coronavirus-demographics-report/index.html
https://www.cnn.com/2020/06/15/politics/cdc-coronavirus-demographics-report/index.html
COVID-19 Pandemic: Transmissions, Deaths, Treatments, Vaccines, Interventions and More...
- Thread starter RU848789
- Start date
- Status
https://apnews.com/89d963958b042cc9...AP&utm_source=Twitter&utm_campaign=SocialFlow
Huge news, big news, or just news?
Huge news, big news, or just news?
Leronlimab is a CCR5 antagonist, phase 3 trials have been completed for HIV treatment and has been tested on over 800 patients. The most common side effects were minor. No drug-related serious adverse events or dose-limiting toxicities among participants were reported. There were also no clinically relevant drug-related effects on ECG among participants. This drug seems to be extremely safe and only has efficacy of treating CV-19 standing in the way.
The question that begs to be asked:Will a vaccine be introduced that is in truth a placebo?Since the yearly flu vaccine never guarantees protection,why wouldn't they attempt it?
Not sure this has been posted here yet—
Study out of the UK with a common steroid to reduce death numbers.
Study out of the UK with a common steroid to reduce death numbers.
Yup just posted it a couple above you. I always said that steroids, not aspirin, is the wonder drug.
Sounds like a game changer. Doesn't help less ill patients, but less ill recover. Looks to have a major impact on severely ill including those on vents.
It says a large strict test, but doesn't say it was a double blind study. Have to wait for the full release.
At least the news is from the AP and BBC not a fringe site.
Last edited:
https://www.cnbc.com/2020/06/16/steroid-dexamethasone-reduces-deaths-from-severe-covid-19-trial.html
Scientists hail dexamethasone as ‘major breakthrough’ in treating coronavirus
Scientists hail dexamethasone as ‘major breakthrough’ in treating coronavirus
I just a minute and thank all of you who are posting the valuable information you have been posting.
For someone without a background in this area it has been very helpful.
For someone without a background in this area it has been very helpful.
Well , who should the United States Government dispense stimulus money to first... legal , native born or naturalized citizens or illegals ? Whose fault is it not filing a tax return for both 2018-2019? Is that on government? Lastly, even after the initial issue with checks , people were told how and what to do in order to recover money from the program . When they failed in their efforts they then start the blame game . I want to see when legally born or naturalized US citizens don’t get their benefits first for that is when the real crap will hit the fan.
Well the early EIND results of 180 patients, say otherwise. Leronlimab has not only reduced or eliminated the cytokines storm and brought down Ig6 , it has regulated T 4, T6, and T8cells to reduce viral load and brings the immune system to homeostasis . It acts as an antiviral as well. Dr. Patterson ‘s paper reporting on the EIND results says Rantes is elevated 5 times in mild to moderate cases and 100 times in severe and critical patients. His company Incelldx, diagnostically measures the readings in 3, 5, 7 and 10 and 14 day intervals. Furthermore Leronlimab has shown to have no severe adverse side effects in 800 people that were part of its Phase 1, 2, and 3 trials for AIDS . Plus it is an injectable that can be given even before hospitalization. So your statement that the drug has significant risk and is not effective is pure hogwash. The only thing that will be proven to you before you can mention it is randomized blind trials. Which is absolutely correct and sound scientifically and medically . Those trials are almost done and by the end of June or early July the FDA will have the results and then we will know for sure if it is a treatment for Covid or not. But your being so dismissive is not fact based on the early use of the drug in 180 EIND’s to date .
Pretty big news - first drug to show significant mortality reductions in a randomized, standard-of-care controlled clinical trial - link to the statement from the Recovery Trial is below. And it's really cheap and relatively easy to synthesize this corticosteroid, which has been around since the late 1950s with use mostly for arthritis and asthma; lots of good general info in the wiki link and the synthesis link. In hindsight, we could have been giving this to 60-80% of hospitalized patients instead of HCQ.
https://www.recoverytrial.net/files/recovery_dexamethasone_statement_160620_final.pdf
https://en.wikipedia.org/wiki/Dexamethasone
https://www.sciencedirect.com/topic... synthesized in a,17α-hydroxyl group is added.
Let’s see what happens after President Trump touts it lol
Was curious if that guy who constantly was touting HCQ if this would be his new thing? They would show him a study how HCQ was ineffective then he would respond by saying "they are not using it correctly, it should only be used within these parameters for it to be effective".. then that would change basically every week.
Either way, this looks very promising, having an easily available and cheap drug helping the cause could be huge.
Give people Remdesivir and this, and there is some hope.
well it’s Cali... California like New Jersey has plenty of money evidently ...oh wait they’re shat ass broke until they boost our property taxes 30% ...
I'm keeping and eye on the Keystone vaccine meeting that is being done online yesterday and today. A PhD from Moderna just spoke - they get good results in mice (which we already knew from their previous studies). Unfortunately she provided precious little info about the human trials - only have neutralizing antibody data for 4 people. I'm not sure why she even bothered presenting. I'm worried they will also will have a scalability problem - 100ug of mRNA per person x millions or billions is a lot of nucleic acid.
The talk right after, however, was from an academic lab in the UK. They are using "self applying" RNA. 1ug or less injected RNA (in nanoparticles) which can then be amplified in the cell. I think he said 1 liter could make 100 million doses at only 75 cents per dose! Very impressive. Clinical trial starts tomorrow.
Good news out of NY and sign things are getting better for now.
From CNN:
New York hospitals can now allow visitors, governor says
New York Gov. Andrew Cuomo said hospitals across the state can now allow visitors as coronavirus numbers continue to improve.
"The numbers look very good," he said at a news conference. "We're going to allow hospitals to accept visitors at their discretion."
Cuomo said that if a hospital chooses to allow visitors, those guests must follow state guidelines, including wearing personal protective equipment and being subject to symptom checks. The visits may be time-limited.
Cuomo also added that group homes can allow visitors starting on Friday, if they follow similar guidelines.
From CNN:
New York hospitals can now allow visitors, governor says
New York Gov. Andrew Cuomo said hospitals across the state can now allow visitors as coronavirus numbers continue to improve.
"The numbers look very good," he said at a news conference. "We're going to allow hospitals to accept visitors at their discretion."
Cuomo said that if a hospital chooses to allow visitors, those guests must follow state guidelines, including wearing personal protective equipment and being subject to symptom checks. The visits may be time-limited.
Cuomo also added that group homes can allow visitors starting on Friday, if they follow similar guidelines.
Understood - I was talking more generally about risks from drugs targeted at human proteins likely being greater than those targeted at the actual virus. Also, safety information from HIV trials may not translate well to trials on COVID patients - which is why we need to see the controlled trial results.
Sounds like Cytodyn has completed enrollment for its phase II, 75-patient randomized/controlled trial in mild to moderate COVID patients - do you know when results from that will be published? The EIND study is not controlled (it's emergency use data) - do you have a link to some paper or report on the EIND results to date? Surely you understand the skepticism given so many false claims out there on other drugs, combined with your "take my word for it" posts, which include no links to published research. Also, the phase II trial might not be statistically powered well enough (hence it only being phase II) to show definitive efficacy results, especially since most mild/moderate patients recover. Maybe the results will be great and we can all celebrate, but from my perspective I simply haven't seen much yet.
I also didn't say the drug had significant risk or was not effective, since I have no clue about either, clinically, since we haven't seen results from randomized controlled studies yet. I just said it's less likely to be safe and effective than an engineered antibody treatment which targets the virus.
https://www.biotech-capital.com/com...-to-moderate-symptoms-of-covid-19-921739.html
I'm figuring that they may try that gambit if Trump loses.Sorry to drop the other shoe.
Hasn't this been the main concern with Moderna form the beginning? That, if viable, scaling production would be a huge roadblock?
The joke in scientific circles has been, "but what about zinc?"
I'm not in the hospital patient management business, but new admissions wouldn't necessarily be placed immediately in ICU for example, but perhaps 1-2 days if the conditioned worsened. ICU/ventilators #'s would actually be the lagging metric vs. new admissions.
Well that and there's never been an approved mRNA vaccine before...as I said back in March, they would not be my bet to win this. And I'm still disappointed the US is not pursuing at least one weakened/deactivated virus vaccine - it's old school, but tried and true (and China has 3-4 of them under development).
Getting out of here for 6 months and a day. Yea baby!
Unless it’s Andy or Chrissie who , if it were their mother /father , family member , would be given much different guidelines or limitations... Cuomo dangling that carrot again for his poll numbers.
Are you moving to TX or AZ for full-time residency?. (Make it AZ, they may need your common sense and well-informed vote more :Wink:).
I have a couple friends that did a similar move to FL, and keep a "summer" home at Jersey Shore. I'd do the same when my last kid is out of NJ schools--but the wife has already mandated we stay as close as possible where kids/future grandkids live.:Sad:
Illinois (where I am ) is not far behind on this trend. No money, but crank up the property taxes. Chicago raised property taxes and water/sewer cost greatly to get more money.
Zero’ing in on Montana though Az is still a possibility.
Part of the reason for the high taxes in NY/NJ/CT is we get screwed every year and now we're getting screwed by Mitch and friends who won't fund states hardest hit by the coronavirus - which just happen to be states that contribute billions more in federal taxes than they get back in federal expenditures. And Mitch's Kentucky is near the top of those state "welfare" recipients. How about if, instead of being reimbursed for our far higher coronavirus costs, we just get back the $140BB in NY and $90BB in NJ we've overpaid over the last 5 years?
The reason why taxes are so high in those states is overspending and ridiculous pension liabilities.Part of the reason for the high taxes in NY/NJ/CT is we get screwed every year and now we're getting screwed by Mitch and friends who won't fund states hardest hit by the coronavirus - which just happen to be states that contribute billions more in federal taxes than they get back in federal expenditures. And Mitch's Kentucky is near the top of those state "welfare" recipients. How about if, instead of being reimbursed for our far higher coronavirus costs, we just get back the $140BB in NY and $90BB in NJ we've overpaid over the last 5 years?
Part of the reason for the high taxes in NY/NJ/CT is we get screwed every year and now we're getting screwed by Mitch and friends who won't fund states hardest hit by the coronavirus - which just happen to be states that contribute billions more in federal taxes than they get back in federal expenditures. And Mitch's Kentucky is near the top of those state "welfare" recipients. How about if, instead of being reimbursed for our far higher coronavirus costs, we just get back the $140BB in NY and $90BB in NJ we've overpaid over the last 5 years?
Part of the reason for the high taxes in NY/NJ/CT is we get screwed every year and now we're getting screwed by Mitch and friends who won't fund states hardest hit by the coronavirus - which just happen to be states that contribute billions more in federal taxes than they get back in federal expenditures. And Mitch's Kentucky is near the top of those state "welfare" recipients. How about if, instead of being reimbursed for our far higher coronavirus costs, we just get back the $140BB in NY and $90BB in NJ we've overpaid over the last 5 years?
The reason why we get so little back is that we have a very weak congressional delegation. This was very evident during the Base Realignment and Closure the reason why Ft. Monmouth was closed was because if the Military pissed off the NJ Senators and Congressmen then there was very little backlash. This has been this way for years.
- Status
Similar threads
