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COVID-19 Pandemic: Transmissions, Deaths, Treatments, Vaccines, Interventions and More...

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So with these treatments gaining traction, I would think average time in hospital would be a good next level statistic.

Would be helpful to compare those prior to those in the future.

Advances in treatmentv is one variable. I just had this discussion with my son out by the fire tonight. I think viral exposure times is something which is overlooked here.

It must be the alcohol being consumed that has led to a decrease in positive cases and deaths... barley and hops a great combo for a strong immune system.

Cheers to that! I think I have more beer stockpiled at this point than toilet paper.
 
Gilead starting trials for inhaled version of remdesivir....can't be administered by pill because of liver issues.

https://www.cnbc.com/2020/06/22/cor...ls-for-the-inhaled-version-of-remdesivir.html

Scott Gottlieb on states with increasing growth commenting this is a pivotal time coming up to see if they're tipping over to exponential growth. Also says Northeast may seem some increases as things reopen but the rates were driven down a lot before that so any increase is against a different back drop compared to other parts of the country. Also because the Northeast was so hard hit people are more compliant with the health guidelines of masks and distancing.

From the article:

A number of states, mostly across the American South and West, have seen a drastic rise in cases over the past couple of weeks as more people move about in increasingly reopened areas and the virus spreads to new communities.


“I think this week’s going to really be a pivotal week for us to get a picture of where things are heading in states like Florida and Arizona and Texas, whether or not they’re tipping over into exponential growth or not,” Gottlieb said on CNBC’s “Squawk Box.” “The problem is with exponential growth everything looks sort of okay until all of a sudden it doesn’t.”

Officials in some states, including Florida, initially pointed to increased testing as a driver of the spike in new confirmed cases. However, Florida Gov. Ron DeSantis acknowledged that the share of people who test positive is accelerating faster than the number of tests being run. The percentage of people testing positive for the virus in Florida has risen from about 4.2% on June 7 to more than 8% on June 14, the most recent data available, according to the Florida Department of Health.

The number of deaths due to Covid-19 does not appear to be rising along with the number of confirmed cases, Gottlieb said. However, that could be due to the lag in time it takes for infected people to fall ill, become hospitalized and then die. Gottlieb said he doesn’t think the death rate will rise drastically, as doctors have become better at treating patients and more people who get infected are younger and not as vulnerable as the elderly or those with underlying health conditions.

Nonetheless, if such states fail to bring down the rate of spread and contain the virus, Gottlieb said, it will find its way to at-risk communities. The longer officials in these states allow the virus to spread, Gottlieb said, the more difficult it will be to bring it under control.

https://www.cnbc.com/2020/06/22/thi...texas-florida-as-coronavirus-cases-spike.html
 
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Casinos and indoor dining allowed in NJ at 25% capacity beginning 7/2. For once Murphy threw the business community a bone, loosening a restriction at the beginning of a weekend instead of at the end.
 
Casinos and indoor dining allowed in NJ at 25% capacity beginning 7/2. For once Murphy threw the business community a bone, loosening a restriction at the beginning of a weekend instead of at the end.
Interesting, reduced capacity is fine, but what about people using the same slots? Obviously, AC attracts older folks.
 
Casinos and indoor dining allowed in NJ at 25% capacity beginning 7/2. For once Murphy threw the business community a bone, loosening a restriction at the beginning of a weekend instead of at the end.
Well it's a big weekend but you know there's another way to look at opening up a previous restriction on a Monday vs a Friday. All these new guidelines and protocols and extra things they have to account for might be easier to get acclimated to for a few days with a sparser crowd rather than right out of the gate with a busy weekend crowd. So by the time the weekend rolls around you've done whatever new processes for a few days, possibly worked out and discovered kinks and are ready for the bigger weekend crowds and things to be smoother.
 
NJ antibody testing showing much fewer asymptomatic positives than originally thought.

https://www.northjersey.com/story/n...idnt-infect-many-without-symptoms/3216653001/
Interesting, thanks for posting. Probably not a surprise that about 17% of 2000 health care workers in a Teaneck hospital were positive and that 17% of patients from an Englewood private practice tested positive for antibodies, which is pretty close to the 21.6% positive rate for NYC (and 17% for Manhattan), given that Bergen County has been ground zero for NJ. These are obviously not random tests in any way, so they should be taken with a grain of salt, but I'm sure they're in the ballpark for counties close to NYC (Bergen, Hudson, Passaic, Essex, Union and maybe Middlesex, which are the 6 highest for deaths with Bergen/Esssex being the top 2 by some margin).

https://www.nj.gov/health/cd/documents/topics/NCOV/COVID_Confirmed_Case_Summary.pdf

The low rate of people with no symptoms being positive is very likely a function of the "sampling." The NY/Spain-style antibody testing is being done on as random a population as possible, whereas these tests were all done on very narrow populations of people already with symptoms (by doctors) or of people with greater exposures (health care workers). Asymptomatic, but infected rates of 20-40% based on other random sampling and the CDC's estimate of 35% make more sense to me.

I do wish NJ would do some sort of randomized antibody testing for the State, like NY has.
 
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take it elsewhere. this is what will get this thread closed.
Agreed. I'm done with arguing with him, especially once it veered very far from COVID. Personally, I'd like to be able to discuss the politics of the pandemic somewhere on the board, but we've all seen what happens on the CE board and some threads here since that closed, so I respect the position of the mods on this and will not pursue it any further.
 
I know everyone is tired of this virus, but unfortunately, this quote I saw elsewhere today still applies...

“The coronavirus doesn’t care if you’re tired of the coronavirus.”
That’s fair and I am pretty conservative when it comes to this stuff but I don’t see why college football and pro football wouldn’t play. If there are older coaches that are nervous they can sit out if they so chose. These kids are only young once and they are missing out on a huge part of their lives if they don’t play. The risks to them are slim. They could also get paralyzed or die playing in normal times. They know the risks and you let them decide if they want to play or not. My 7 year old is starting baseball tomorrow. We will do the best we can to stay safe but he has to be a kid and make friends and socialize. It’s a crucial point in his life in my opinion. I signed a waiver so I know the risks. I can’t have him sheltered for the next year. I would assume most college football players want to play so let them.
 
A couple of interesting (to me, at least, lol), long posts on the RU-positive-COVID thread that are worth bringing here. Both were in response to a claim that COVID was only 2-3X worse than the flu with regard to overall deaths and that the flu was 6-20X more deadly than COVID for people under 18. Both are wrong, although it took the first post to refute the overall deaths point and the 2nd to refute the one on children. The real math is overall, COVID will likely have a final total infection rate of 0.5-1.0%, overall, vs. 0.08% for the flu, plus COVID will eventually infect 5.5-8X the numbers infected by the flu every year, which is why 900K-2.6MM eventual COVID deaths are possible (w/o interventions or a cure/vaccine). And in the 2nd post, once I found actual reported US death rates for those under 18 for both COVID and influenza (flu deaths are estimated for every age group, but actual deaths are reported for those under 18) it became pretty clear that the death rates are likely pretty similar, with flu maybe having 2X the death rate for that age group (not 6-20X) at worst, depending on assumptions.

https://rutgers.forums.rivals.com/threads/two-ru-players-test-positive-for-cv19.198591/page-2

The short version for T, who can't read more than a sentence or two: kyk's graphic is very misleading using incorrect data comparisons, death rates for COVID are currently ~13X greater than for a typical influenza season, overall, and flu is maybe 2X more deadly than COVID in children, so far, but there's still a ton we don't know about COVID in children, especially with MIS-C.

That "graphic" of COVID vs. influenza deaths by age group is very misleading and was constructed by FREOPP, a right wing think tank, from CDC data, but using inappropriate data (kyk - you really should cite sources). In the first link below, where the that graphic was taken from, the authors assume an average annual deaths from "influenza and pneumonia" of 60,000 per year, which is an estimate and is what the CDC reports, but it's irrelevant if we want to compare COVID to the flu since there are many sources of pneumonia in any given year, not just influenza.

https://freopp.org/estimating-the-r...vs-influenza-or-pneumonia-by-age-630aea3ae5a9

The estimate most people use for influenza deaths is ~30K/year, which is the average over 2010-11 to 2016-17 (the last 2 years are "preliminary estimates" and not included; see the 2nd link). However, keep in mind that this is an estimate made from models (not actual reported deaths, like we have for COVID) and is likely much higher than the true influenza death rate, since it includes bacterial pneumonia and other sources of death lumped in with influenza, as per the 3rd link from Scientific American where the author said, "In the last six flu seasons, the CDC’s reported number of actual confirmed flu deaths—that is, counting flu deaths the way we are currently counting deaths from the coronavirus—has ranged from 3,448 to 15,620, which is far lower than the numbers commonly repeated by public officials and even public health experts."

https://www.cdc.gov/flu/about/burden/past-seasons.html
https://blogs.scientificamerican.co...u-deaths-is-like-comparing-apples-to-oranges/

However, even if we use the somewhat inflated 30K estimate of average flu deaths per year that's still not an apples to apples comparison with COVID. Over those same 8 years, the CDC data show that, on average, there are an estimated (again from models) 22.3MM symptomatic flu cases per season, which is about 6.8% of the population; that 30K/22.3MM ratio is the symptomatic infection fatality rate (SIFR), which is 0.13%. However, to get a true comparison of apples to apples we need to know the infection fatality rate including asymptomatic cases of the flu, which the Scientific American paper estimates could be 50% and the CDC estimates is around 40% (link below). Let's be conservative and use 35%, which is the same number that the CDC is currently projecting for the % of asymptomatic COVID cases - that would give a 0.08% total infection fatality rate (TIFR).

https://www.cdc.gov/flu/about/keyfacts.htm#:~:text=The commonly cited 5% to,didn't have any symptoms.

So, from a big picture perspective, comparing TIFRs for flu vs. COVID, the comparison, then, is 0.08% for flu vs. 1.1-1.2% for COVID, which is based on the New York and Spain deaths vs. seroprevalence data from antibody testing a reasonable subset of the population. Specifically, for NY, there were 30,700 dead as of 6/13, which is an infection fatality ratio of 1.1% (vs. 2.68MM infected, given 20MM in NY with 13.4% with antibodies, which includes asymptomatic infections), which is up a bit from the 1.0% it was back on 5/1. So the apples to apples TIFRs are 0.08% to 1.1%, meaning COVID is 13.7X deadlier than the flu, overall, so far.

Having said that, I've been saying all along and most experts seem to agree that the eventual COVID TIFR will be 0.5-1.0%, since it's possible more vulnerable people have been infected so far and since doctors are getting better at treating COVID (once there's a near cure or vaccine, the TIFR will change completely, though - for now, we're discussing pre-cure/vaccine IFRs for comparison). One more thing: in an average year only about 34MM people are infected by the flu (including asymptomatics), which is slightly over 10% of the US: for us to reach "herd immunity" in the US for COVID we'd need to have 55-80% infected, depending on who's R0 transmission estimates one believes, which is more than 5X as many people as get infected with the flu in a typical year - so IFRs are deaths per infection, but if there are 5X as many infections, the deaths go up that much more over time. It's why anyone saying COVID is no worse than the flu, overall, is simply nuts.

https://rutgers.forums.rivals.com/t...entions-and-more.191275/page-189#post-4613691

It's much harder to find good mortality data by age group for the entire US. If someone has it, please share. Until then, I'll use NY's data, which has been the best data so far, especially since they have a decent breakdown of deaths by age and they have antibody testing. As of now, NY lists 15 deaths for the 0-17 year old age group, which would extrapolate to roughly 250 deaths for the US if NYC's rate held. Obviously, NY's death rate per 1MM is higher than everyone else's now, but that's only because NY has far more cases per 1MM (the ratio of deaths per cases is much more similar across most of the US than deaths/1MM), so IMO, it's reasonable to use NY to project eventual US numbers.

https://covid19tracker.health.ny.gov/views/NYS-COVID19-Tracker/NYSDOHCOVID-19Tracker-Fatalities?:embed=yes&:toolbar=no&:tabs=n

So, then one would compare an estimated 250 COVID deaths in the 0-17 age group to the average of roughly 450 deaths in the 0-17 year group for an "average" flu season (same CDC link). Yes, flu looks to be maybe ~2X more deadly than COVID for children (but not the 6-20X more deadly in that graphic), but then again, there's still a lot we don't know about COVID, especially the very serious MIS-C (multisymptom inflammatory syndrome - children) that is being seen much more lately (over 200 cases in NY/NJ so far) and has proven deadly in some cases (and may have been missed before).

As I said above, I think a much better apples to apples comparison of COVID to influenza would be actual counted deaths from ages 0-17 (or any age group really). Well, I finally found the COVID CDC reported US age group deaths through 6/13 (103K total vs. 117K total on Worldometers on that date - it's known the CDC data lag, so they're going to be on the low side). And I finally found the CDC actual reported deaths for influenza for pediatric cases (ages 0-17), which have been reported for almost 20 years. It really shouldn't be this hard to find everything, but it is. So let's have a look, although the spoiler alert is it confirms what I said last night, that actual pediatric deaths for flu are likely only a little bit higher, not 6-20X higher.

The first link has the CDC data on COVID mortality by age and it shows 26 deaths from ages 0-14 and 125 deaths from 15-24, which would equate to ~12 deaths per 1 year increment if they were equal risk, but they're not, so let's say deaths for 15-17 are half those of 18-24 to be conservative. That would mean 18 more deaths for 15-17, making a total of 44 deaths from 0-17, by the CDC numbers and let's add 14% (6 of 44) to that, since the CDC count is 14% behind the real count, making a total of 50 deaths from 0-17. My guess is this number is fairly conservative, since extrapolating NY's 15 deaths in ages 0-19 to the US (333MM/20MM - relative populations) would give 250 deaths and even if we took 20% off that (since 0-19 is not 0-17 - a 10% difference, but doubling it since there should be more deaths for 18-19 vs. 0-17) it's still 200 deaths from 0-17 vs. the CDC number of 50. Or we could just say the COVID number is likely between about 50 and 200 deaths for 0-17 year olds.

https://data.cdc.gov/NCHS/Provisional-COVID-19-Death-Counts-by-Sex-Age-and-S/9bhg-hcku

The CDC estimated 8-year average flu deaths in the 0-17 age group of ~450 I calculated in last night's post certainly sounds a lot worse than the actual COVID deaths, but as mentioned in the previous post, flu deaths are estimated by a fairly complex model. However, for children, 0-17, the CDC actually has true death counts, since those had to be reported by every state to the CDC since 2004 an those actual reported flu deaths have ranged from 37 (2011-2012 season) to 185 deaths (2017-2018 season), as per the 2nd link below, with an average number of age 0-17 flu deaths being about 120 per season (for the same 8 years as in the post above: 2010-11 thru 2017-18).

https://www.cdc.gov/flu/about/burden/faq.htm
https://gis.cdc.gov/grasp/fluview/pedfludeath.html

Comparing that 120 actual CDC flu deaths for 0-17 to the range of 50-200 I just estimated from the COVID data (US vs. NY) means the differences are not very large. Even if we only took the US-CDC COVID number (~50), the ratio is 2.4X, which is nowhere near the 6-20X postulated in kyk's graphic, but I think it's just as likely that there's no significant difference. This is in sharp contrast to the huge difference in the total infection fatality (TIFR) rate for COVID in the overall population vs. influenza, as I showed in last night's post, if one assumes a TIFR of 0.5-1.0% for COVID (it's 1.1% for NY now) vs.0.08% TIFR for the US for flu, giving a ratio of 6.25-12.5X for TIFRs for COVID compared to flu.

Going one step further, if the TIFR ratio is 6.2-12.5 and we have 30K estimated flu deaths per year, that's 186K-372K COVID deaths. However, as per last night's post, only about 10% of the total US population gets infected by flu every year (34MM, including asymptomatics), whereas COVID would infect 55-80% of the US based on herd immunity or 5.5-8.0X more people than flu, so multiplying just by the low end of that range (5X), we could see 930K-1860K US deaths eventually (I've been saying 900K-2600K in other posts using just the 0.5-1.0% COVID IFR times that full 5.5-8.0X multiplier, which gives 181MM-264MM infected), assuming no interventions, cure or vaccine and since we can't count on cures/vaccines (even though I think we could have a cure by Sept and a vaccine by Dec), we have to have more aggressive interventions if we want to decrease our death rates significantly, i.e., distancing first, with masks if distancing isn't possible, combined with aggressive testing, tracing and isolating (we're doing good on testing, but not on tracing/isolating).
 
Isn't Qatar using slave labor to build World Cup sites?? Those people have no money!

This is way outside the scope of this thread, but with the resurgence of interest across the globe in social justice, I have a hard time believing there won't be a major hue and cry about holding the World Cup in 2022 in an Islamic state that has some fairly draconian gender laws, despite women making huge advancements in Qatar over the past 20-30 years. The counterargument is that maybe holding it there with the huge influx of women soccer fans would significantly benefit women in Qatar and other Islamic countries. Good topic for a new thread...
 
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This is way outside the scope of this thread, but with the resurgence of interest across the globe in social justice, I have a hard time believing there won't be a major hue and cry about holding the World Cup in 2022 in an Islamic state that has some fairly draconian gender laws, despite women making huge advancements in Qatar over the past 20-30 years. The counterargument is that maybe holding it there with the huge influx of women soccer fans would significantly benefit women in Qatar and other Islamic countries. Good topic for a new thread...
There is many reasons not to have it there. The biggest is it hot as hell there. Nothing policy about that. FIFA Leadership got paid millions. Another corrupt organization.
 
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This is way outside the scope of this thread, but with the resurgence of interest across the globe in social justice, I have a hard time believing there won't be a major hue and cry about holding the World Cup in 2022 in an Islamic state that has some fairly draconian gender laws, despite women making huge advancements in Qatar over the past 20-30 years. The counterargument is that maybe holding it there with the huge influx of women soccer fans would significantly benefit women in Qatar and other Islamic countries. Good topic for a new thread...


because there is a lot of hypocrisy in global social justice....alot
 
because there is a lot of hypocrisy in global social justice....alot
There are too many who in our “global justice” history bash our Nation’s sordid past but uphold and even dignify countries like China, Venezuela, Cuba and all the Middle East ( except Israel ) ...yes bac hypocrisy at it’s penultimate.
 
There are too many who in our “global justice” history bash our Nation’s sordid past but uphold and even dignify countries like China, Venezuela, Cuba and all the Middle East ( except Israel ) ...yes bac hypocrisy at it’s penultimate.
I've never heard penultimate used the way I think you're intending.
 
NJ's numbers today were silly good. Without checking, there are appx:
1030 hospitalized
under 300 new cases yesterday
under 30 deaths yesterday

Usual early week reporting caveats apply.
And above is part of the reason sports will be played this fall.
 
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We can agree on that, although it doesn't mean the efforts are "wrong" - just not always consistent and well thought out - the world is a messy place sometimes...
Agreed there is good and right inSOCIAL JUSTICE but what we are seeing in Seattle, DC, NY, Virginia, San Francisco , Charlotte is NOT SOCIAL JUSTICE... it is simply a new political party bent on destruction of America as we know it.....if you are part of that than you are not for SOCIAL JUSTICE... Not you personally Numbers....
 
And above is part of the reason sports will be played this fall.
Not so fast on that prediction... if school isn’t back and it appears most students will not be on their campuses for Fall... they are not playing....
 
Not so fast on that prediction... if school isn’t back and it appears most students will not be on their campuses for Fall... they are not playing....
tons of schools have announced that students will be in campus for the fall
 
Agreed there is good and right inSOCIAL JUSTICE but what we are seeing in Seattle, DC, NY, Virginia, San Francisco , Charlotte is NOT SOCIAL JUSTICE... it is simply a new political party bent on destruction of America as we know it.....if you are part of that than you are not for SOCIAL JUSTICE... Not you personally Numbers....
We disagree on that, but that's ok. Can I suggest we leave it at that and get back to COVID, since I doubt either of us is going to change each other's mind by typing a lot more?
 
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We disagree on that, but that's ok. Can I suggest we leave it at that and get back to COVID, since I doubt either of us is going to change each other's mind by typing a lot more?
So you like what you see in tearing down monuments even if they have nothing to do with what occurred during slavery... occupying city blocks Is a good thing while business owners and people that live in fear for what is next ... You don’t see anything wrong with that? ...You may have a ton of education but honestly you are really sick... To see that as Social Justice is what makes you a very ignorant individual... You must really hate this country to believe that it’s just and right... Social Justice is far different than that... this is an attempt to vilify another race in order to justify and acquire power and control... the exact same thing this group says they are protesting against... it’s going to lead to something neither us should want to see ...
 
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tons of schools have announced that students will be in campus for the fall
Maybe... there are still several months until classes start normally ... and it is dependent upon what continues in other areas of the country ...I would love me some football but even Schiano’s not sure.
 
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Back to COVID with a fascinating and very insightful edition of "In The Pipeline" by Derek Lowe in Science Translational Medicine. If there's one scientific article you should try to read and understand with regard to the many potential "futures" of this outbreak it's this one, IMO. It's aptly titled, "Thoughts on Antibody Persistence and the Pandemic." Does a fantastic job of exploring the uncertainty associated with antibody persistence and T-cell activity in infected/recovered people, both symptomatic and asymptomatic and what that means for post-infection immunity (including will people have it and if so for how long) and eventual immunity for people treated with antibodies and vaccines to produce antibodies. The article (including the excerpt in italics) and the Nature paper upon which some of the article is based are linked below. Enjoy.

https://blogs.sciencemag.org/pipeli...ghts-on-antibody-persistence-and-the-pandemic

https://www.nature.com/articles/s41591-020-0965-6

That uncertainty extends deep into the biology of the disease. Let’s illustrate that with a look at a paper that’s come out recently that has shaken a lot of people up. It’s a valuable look at a controversial topic: people who have definitely been infected with the coronavirus, but who are asymptomatic. There are very important questions about this situation, among them how infectious such patients are and for how long, what might be different in their immune response as compared to people who become more overtly ill, and how the longer term effects on immunity might differ as well. And not least: how many such asymptomatic patients are there in general, and are they more common among some parts of the population than others? All of these questions are very important to our understanding of the pandemic and our responses to it, and none of them are as well-worked-out as we need them to be...

...So my advice is not to panic, but not to be complacent, either. The complexities of the immune system mean that we have a whole range of possible situations in how this pandemic is unfolding. At the most optimistic end, it is possible that a larger percentage of the population than we realize might already be protected (to some degree) from the coronavirus. Unfortunately, it’s also possible that almost everyone is, in fact, still vulnerable and that we just haven’t seen the virus run through most of the population yet. Everyone will have seen the various population surveys with antibody testing that have suggested, in most cases, that a rather small percentage of people have been exposed. Think of the various ways you could get such a result: (1) it’s just what it looks like, and most people are unprotected because they have so far been unexposed. (2) the antibody results are what they look like – low exposure – but people’s T-cell responses mean that there are actually more people protected than we realize. (3) the antibody results are deceiving, because (as this latest paper seems to show) the antibody response fades over time, meaning that more people have been exposed than it looks like. And that means you can split that into (3a) the antibody response fades, but the T-cell response is still protective and (3b) the antibody response fades and so does the T-cell response. That last one is not a happy possibility.
 
So you like what you see in tearing down monuments even if they have nothing to do with what occurred during slavery... occupying city blocks Is a good thing while business owners and people that live in fear for what is next ... You don’t see anything wrong with that? ...You may have a ton of education but honestly you are really sick... To see that as Social Justice is what makes you a very ignorant individual... You must really hate this country to believe that it’s just and right... Social Justice is far different than that... this is an attempt to vilify another race in order to justify and acquire power and control... the exact same thing this group says they are protesting against... it’s going to lead to something neither us should want to see ...
Exhibit A for why the CE boards got shut down and why this thread is always at risk.
 
Well, this study removes any shred of doubt about the importance of requiring masks to be worn. All 18 countries who did this early on have had <10 deaths per 1MM, while the US and most of Europe, which did not require masks until much later in their outbreaks (if at all) generally have had over 400 deaths/1MM, roughly 50-100X more (and we're not done, sadly). Much of South/Central America are on their way to similar high death rates, except Venezuela, which required masks from day one and has 1 death/1MM. It's so simple, yet our leadership and a sizable segment of our population just can't or won't see it.

https://www.researchgate.net/public...d_public_wearing_of_masks_Update_June_15_2020

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