ADVERTISEMENT

COVID-19 Pandemic: Transmissions, Deaths, Treatments, Vaccines, Interventions and More...

Status
Not open for further replies.
This "study" seems to point toward something I've been thinking - that we need to test these drugs in people who are relatively early in the disease course, to prevent them from deteriorating to the point where they need ICU treatment or ventilator support. A lot of what was reported early, especially negative or inconclusive results, seemed to be people who were already in severe or critical condition. Assuming those people are suffering more from immune system dysfunction (cytokine storm type thing) I would not necessarily expect anti-viral drugs to have much impact for them. We need to prevent them from getting to that point.
Those studies are ongoing and need hundreds, if not thousands of patients to see a real effect, since the vast majority of mildly symptomatic patients get better on their own, which makes determining efficacy very difficult without very large numbers of patients.
 
I've been taking my temp multiple times a day for six weeks. Been around 98.2 the whole time (according to my thermometer anyway)

Taking it the old fashioned way?

This "study" seems to point toward something I've been thinking - that we need to test these drugs in people who are relatively early in the disease course, to prevent them from deteriorating to the point where they need ICU treatment or ventilator support. A lot of what was reported early, especially negative or inconclusive results, seemed to be people who were already in severe or critical condition. Assuming those people are suffering more from immune system dysfunction (cytokine storm type thing) I would not necessarily expect anti-viral drugs to have much impact for them. We need to prevent them from getting to that point.

Exactly. But because the people who reach this point is a smaller percentage of all positively identified patients, it would probably not be realistic or feasible to treat everyone prophalactically. What is happening in some places, is when the pulmonary decline is starting, they are hitting the patient with chloroquine, antivirals AND an interleukin 6 binding agent to help prevent the impending cytokine release syndrome. Everyone is throwing Hail Marys and hoping something sticks. Attacking the IL-6 receptors is interesting.

Well I just took my blood alcohol level, and it w............oh, wait, never mind. And, yes, I'm good also!

I might increase my BAC a little tonight.
 
One more reason that not having a national shutdown and better federal leadership is a travesty. These states without social distancing (SD) are as dumb as the entire US was a month ago in not seeing what was coming and how to mitigate it, based on the SK/China models, but now that we know a lot more about how SD can help, even in NYC, for these other states to not be following the SD model is just nuts and that's on the Administration.

SD and reducing travel works (along with aggressive testing/tracing/quarantining), as per Fauci's comment below, which is being borne out in the WA and NY now showing the slowest case growth rates in the US. See the table below showing the differences in case growth rates in selected states and it's easy to see why the growth is so much more in those states that are highest, as those are the states in the map from the Times that generally haven't been practicing SD/reducing travel.

Other areas reduced travel weeks ago, the data show, especially in California, New York and Washington, which were the first to experience large outbreaks. Most people have essentially stopped traveling in those places for weeks, the data show, a sign that they are taking the measures seriously. Anthony S. Fauci, the nation’s leading infectious disease expert, said on Tuesday that changes in behavior were already bringing down the level of new cases in those places.

https://www.nytimes.com/interactive...-distancing.html?referringSource=articleShare

It also doesn't help that we have some morons as governors. It's almost unfathomable that the GA governor in announcing the stay at home order yesterday said that he "just learned that the virus transmits asymptomatically," which has been known for well over a month. These states without restrictions are very likely going to be hit even harder.

https://www.washingtonpost.com/poli...just-learned-it-transmitted-asymptomatically/

image.png.ff1fddf0977313f9590ce36481826278.png


Gg9TDtk.png
 
  • Like
Reactions: 93RUDoc
The improved virus testing is great to get a better handle on this outbreak, but until we have widespread antibody tests (becoming available now), there's simply no way we can go back to life as it used to be. We'll likely have <1% of the population infected (1% would be 3MM and we have 214K positive cases now) when we hopefully get past this first wave, which means 99% of the population could still get the virus, meaning it will still spread like wildfire if we go back to normal life.

Unless there are 5-10X the number of people who test positive to the virus who actually became infected, but never had symptoms and/or were never tested - this is possible based on the Diamond Princess, where ~10% of the passengers tested positive for the virus but had no symptoms and they should have the antibodies and be immune (they tested everyone on the boat), but we'll only find out when we do major antibody testing, including on some representative large samples of the population from selected locations like NYC.

If we had those kinds of numbers of people with antibodies, that would likely slow down transmission rates somewhat in the future, but I still think many will choose to stay out of harm's way until we have a proven treatment or preventative (antibody therapy, either from plasma or engineered) or vaccine. I'll be in that group, given the risks of COVID-19 to my wife and son (asthmatic and immunocompromised).
I agree the antibody therapy and the knowledge gained to determine who cannot get the virus again is definitely critical to a return to normal but I am just speaking of getting NJ fixed. The screwup in testing knowing we were 2 weeks behind NY at one time should have ramped up testing and it wasn’t and it was a fail. I want to hear the Abbott test or the Rutgers test(45 minutes involving spitting ) has been rolled out but at today’s presser with Murphy or at least the part I heard, no mention or questions about those tests. There was an admission that the existing tests have people waiting 10-12 days for results has been troublesome. Private companies should have been solicited , and engaged to administer tests earlier.
 
  • Like
Reactions: bac2therac
Yeah, I've been doing that too. Nice daily rhythm, typically around 97.5 in morning, up to between 98.5 and 99 in the late afternoon/evening, back down to 98 or lower late in the evening.
Interesting. What type of thermometer?

I probably should do this with everyone in family so we have an accurate baseline for now and I the future

had no idea body temperature would fluctuate in a predictable fashion
 
Interesting. What type of thermometer?

I probably should do this with everyone in family so we have an accurate baseline for now and I the future

had no idea body temperature would fluctuate in a predictable fashion
Temp can vary throughout the day, although the example above is more than one would expect; also different people have different "baseline temps." Mine is 98.7F, my wife's is around 98.4F and our son's is 97.4F (and these rarely vary more than 0.2-0.3F around the mean), which was really important to know, since he got sick a ton as a kid (immuncompromised as I mentioned) and 98.6F generally meant a low grade fever for him and over 100F was a significant fever. Whenever he got above 102F and was having breathing problems (has asthma), we'd go to the ER to get nebulizer therapy (about 5-6 times when he was a kid, mostly when he was under 3, when it's harder to do this at home), as per his doc's instructions.
 
It took 7 days, sadly, as we just hit 1049 deaths in one day on Wednesday. would be a small "victory" of sorts (relative to where we are now, not in general) if we can stay below 2000/day, as it's at least well below the ~4300/day we'd expect if we had the same per capita deaths as Italy (they had a sustained 780/day for 9 days and we have 5.5X their population). Also, as expected our case fatality rate has jumped up to around 2.5%, since we're now seeing more deaths per day, as deaths lag cases.

If we can keep it under 2000/day, over a 10-20 day peak, we have a shot at keeping to under 60K total deaths and could probably prevent overwhelming most of our hospitals. If we go to Italy's rates per capita, we'll likely see at least 100K deaths; both of those numbers suck, but 100K certainly is much worse and at those rates, we'd likely overwhelm many of our hospitals.

Also as of Monday, NY had slightly over 50% of the total deaths in the US, but by Wednesday that dropped to 43%, meaning the rest of the country is accelerating faster than NY and much of the rest of the country is not as prepared as NY has been, at least with regard to social distancing, as many states have either no stay at home orders or weak ones. We're simply not being proactive enough - need a nationwide "stay at home" order now, like the Surgeon General implied today.

oD51nDo.png
That graph does not bode well for keeping deaths under 2K/day. Will definitely be one of the more important graphs to track through April/May when looking at the endgame.
 
Numbers...any info available on how long coronavirus can live on grass, shrubs, leafy debris, weeds and other foliage. Also how long on asphalt, sidewalk and paved surfaces

Thanks
 
Interesting. What type of thermometer?

I probably should do this with everyone in family so we have an accurate baseline for now and I the future

had no idea body temperature would fluctuate in a predictable fashion
There is definitely a daily pattern, I think most people have it but not sure how large it is or whether my range is larger than typical. But it's been very regular for me, some small variations day to day but overall very similar. I actually still have one of the old style mercury thermometers which is what I use most of the time. Have an electronic one that usually decides it's "done" a little early (runs a couple of tenths of a degree below the mercury one).
 
One more reason that not having a national shutdown and better federal leadership is a travesty. These states without social distancing (SD) are as dumb as the entire US was a month ago in not seeing what was coming and how to mitigate it, based on the SK/China models, but now that we know a lot more about how SD can help, even in NYC, for these other states to not be following the SD model is just nuts and that's on the Administration.

SD and reducing travel works (along with aggressive testing/tracing/quarantining), as per Fauci's comment below, which is being borne out in the WA and NY now showing the slowest case growth rates in the US. See the table below showing the differences in case growth rates in selected states and it's easy to see why the growth is so much more in those states that are highest, as those are the states in the map from the Times that generally haven't been practicing SD/reducing travel.

Other areas reduced travel weeks ago, the data show, especially in California, New York and Washington, which were the first to experience large outbreaks. Most people have essentially stopped traveling in those places for weeks, the data show, a sign that they are taking the measures seriously. Anthony S. Fauci, the nation’s leading infectious disease expert, said on Tuesday that changes in behavior were already bringing down the level of new cases in those places.

https://www.nytimes.com/interactive...-distancing.html?referringSource=articleShare

It also doesn't help that we have some morons as governors. It's almost unfathomable that the GA governor in announcing the stay at home order yesterday said that he "just learned that the virus transmits asymptomatically," which has been known for well over a month. These states without restrictions are very likely going to be hit even harder.

https://www.washingtonpost.com/poli...just-learned-it-transmitted-asymptomatically/

image.png.ff1fddf0977313f9590ce36481826278.png


Gg9TDtk.png

I think using distance traveled alone is not a great indicator of measuring potential viral spread, I think you would need to include population density along with distance traveled to get a better picture. As an extreme example the farmer in rural Miss who has to travel from his farm 5 miles to the local store as opposed to the Brooklyn apartment dweller who travels from their apartment in an elevator and then walks 25 yards to the local store. The Brooklynite has many more primary and secondary encounters than the farmer.
 
One more reason that not having a national shutdown and better federal leadership is a travesty. These states without social distancing (SD) are as dumb as the entire US was a month ago in not seeing what was coming and how to mitigate it, based on the SK/China models, but now that we know a lot more about how SD can help, even in NYC, for these other states to not be following the SD model is just nuts and that's on the Administration.

SD and reducing travel works (along with aggressive testing/tracing/quarantining), as per Fauci's comment below, which is being borne out in the WA and NY now showing the slowest case growth rates in the US. See the table below showing the differences in case growth rates in selected states and it's easy to see why the growth is so much more in those states that are highest, as those are the states in the map from the Times that generally haven't been practicing SD/reducing travel.

Other areas reduced travel weeks ago, the data show, especially in California, New York and Washington, which were the first to experience large outbreaks. Most people have essentially stopped traveling in those places for weeks, the data show, a sign that they are taking the measures seriously. Anthony S. Fauci, the nation’s leading infectious disease expert, said on Tuesday that changes in behavior were already bringing down the level of new cases in those places.

https://www.nytimes.com/interactive...-distancing.html?referringSource=articleShare

It also doesn't help that we have some morons as governors. It's almost unfathomable that the GA governor in announcing the stay at home order yesterday said that he "just learned that the virus transmits asymptomatically," which has been known for well over a month. These states without restrictions are very likely going to be hit even harder.

https://www.washingtonpost.com/poli...just-learned-it-transmitted-asymptomatically/

image.png.ff1fddf0977313f9590ce36481826278.png


Gg9TDtk.png
" LEADERSHIP IS A TRAVESTY"
PLEASE take your politcs to the other board. How many times do we have to hear it from you.
 
One more reason that not having a national shutdown and better federal leadership is a travesty. These states without social distancing (SD) are as dumb as the entire US was a month ago in not seeing what was coming and how to mitigate it, based on the SK/China models, but now that we know a lot more about how SD can help, even in NYC, for these other states to not be following the SD model is just nuts and that's on the Administration.

SD and reducing travel works (along with aggressive testing/tracing/quarantining), as per Fauci's comment below, which is being borne out in the WA and NY now showing the slowest case growth rates in the US. See the table below showing the differences in case growth rates in selected states and it's easy to see why the growth is so much more in those states that are highest, as those are the states in the map from the Times that generally haven't been practicing SD/reducing travel.

Other areas reduced travel weeks ago, the data show, especially in California, New York and Washington, which were the first to experience large outbreaks. Most people have essentially stopped traveling in those places for weeks, the data show, a sign that they are taking the measures seriously. Anthony S. Fauci, the nation’s leading infectious disease expert, said on Tuesday that changes in behavior were already bringing down the level of new cases in those places.

https://www.nytimes.com/interactive...-distancing.html?referringSource=articleShare

It also doesn't help that we have some morons as governors. It's almost unfathomable that the GA governor in announcing the stay at home order yesterday said that he "just learned that the virus transmits asymptomatically," which has been known for well over a month. These states without restrictions are very likely going to be hit even harder.

https://www.washingtonpost.com/poli...just-learned-it-transmitted-asymptomatically/

image.png.ff1fddf0977313f9590ce36481826278.png


Gg9TDtk.png

Also, a National Shutdown may not be constitutional.

https://www.barrons.com/articles/a-...t-the-government-could-do-instead-51584399648
 
Numbers...any info available on how long coronavirus can live on grass, shrubs, leafy debris, weeds and other foliage. Also how long on asphalt, sidewalk and paved surfaces

Thanks
UV radiation should deactivate the virus quickly, so as long as the area/materials are getting some direct sunlight. Harder to know how long it would be viable on shaded surfaces/materials, but there should also be very, very little virus on lawns and roads and trees/shrubs to begin with, so I think you have one of the safest jobs out there. Just wash your hands frequently with soap and water and you'll likely be fine - your biggest risk is probably getting too close to your clients.

https://www.weforum.org/agenda/2020/03/this-is-how-long-coronavirus-lives-on-surfaces

"For items that are hard to clean, sunshine may be valuable. Leave your shoes outside, soles up, in the sun. Coronaviruses begin degrading quickly in temperatures higher than 56 degrees Celsius, and in direct UV light."
 
  • Like
Reactions: redking
This is potentially freakin' huge news about the convalescent plasma-antibody treatment approach. Now this is a guy who actually has some results worth screaming to the media about, but he first published it (in JAMA a respected medical journal) and is being circumspect, as he should be, since it was an uncontrolled, unblinded small study, but 5 for 5 with treatment success of people on ventilators is impressive. However, let's wait a week or two and I'm confident we'll see even more good news (this was a Chinese study with technology similar to what they're now using in NYC at Mt Sinai and elsewhere, so should have news from there soon), as this technology should simply just work, like it has in the past. Should also work as a preventative. Seriously crossing fingers.

Findings: In this uncontrolled case series of 5 critically ill patients with COVID-19 and acute respiratory distress syndrome (ARDS), administration of convalescent plasma containing neutralizing antibody was followed by an improvement in clinical status.

Conclusions: In this preliminary uncontrolled case series of 5 critically ill patients with COVID-19 and ARDS, administration of convalescent plasma containing neutralizing antibody was followed by improvement in the patients’ clinical status. The limited sample size and study design preclude a definitive statement about the potential effectiveness of this treatment, and these observations require evaluation in clinical trials.


https://jamanetwork.com/journals/jama/fullarticle/2763983?resultClick=1

https://www.healio.com/hematology-oncology/hematology/news/online/{75453a03-ea98-4c57-8b50-7997853beabe}/convalescent-plasma-transfusion-shows-promise-for-severely-ill-patients-with-covid-19

Edit: Good editorial in JAMA discussing the limitations of this very small experiment, but also the potential for this treatment, too, in the bigger picture, including what this all means and outlining what we could do, should this prove successful in larger scale triials.

https://jamanetwork.com/journals/jama/fullarticle/2763982
 
Last edited:
This is potentially freakin' huge. Now this is a guy who actually has some results worth screaming to the media about, but he first published it (in JAMA a respected medical journal) and is being circumspect, as he should be, since it was an uncontrolled, unblinded small study, but 5 for 5 with treatment success of people on ventilators is impressive. However, let's wait a week or two and I'm confident we'll see even more good news (this was a Chinese study with technology similar to what they're now using in NYC at Mt Sinai and elsewhere, so should have news from there soon), as this technology should simply just work, like it has in the past. Should also work as a preventative. Seriously crossing fingers.

Findings: In this uncontrolled case series of 5 critically ill patients with COVID-19 and acute respiratory distress syndrome (ARDS), administration of convalescent plasma containing neutralizing antibody was followed by an improvement in clinical status.

Conclusions: In this preliminary uncontrolled case series of 5 critically ill patients with COVID-19 and ARDS, administration of convalescent plasma containing neutralizing antibody was followed by improvement in the patients’ clinical status. The limited sample size and study design preclude a definitive statement about the potential effectiveness of this treatment, and these observations require evaluation in clinical trials.


https://jamanetwork.com/journals/jama/fullarticle/2763983?resultClick=1

https://www.healio.com/hematology-oncology/hematology/news/online/{75453a03-ea98-4c57-8b50-7997853beabe}/convalescent-plasma-transfusion-shows-promise-for-severely-ill-patients-with-covid-19
This should work for those cases where high viral load is present. The questions I have revolve around the scalability and whether the process could be made efficient enough to treat people before they wind up with full blown ARDS and on a ventilator. Can this be scaled up to treat hundreds or thousands of patients in an efficient manner?

The other related question would be, why are these particular patients not able to clear the virus on their own? Does the virus damage the immune system or is there something about their genetics that causes them to be unable to produce their own antibodies?
 
UV radiation should deactivate the virus quickly, so as long as the area/materials are getting some direct sunlight. Harder to know how long it would be viable on shaded surfaces/materials, but there should also be very, very little virus on lawns and roads and trees/shrubs to begin with, so I think you have one of the safest jobs out there. Just wash your hands frequently with soap and water and you'll likely be fine - your biggest risk is probably getting too close to your clients.

https://www.weforum.org/agenda/2020/03/this-is-how-long-coronavirus-lives-on-surfaces

"For items that are hard to clean, sunshine may be valuable. Leave your shoes outside, soles up, in the sun. Coronaviruses begin degrading quickly in temperatures higher than 56 degrees Celsius, and in direct UV light."


His biggest risk is me in that I greet him with a nice brotherly hug when he arrives.
Actually we were wondering if using a backpack blower to blow grass, leaves and the such around is harmful.
 
This should work for those cases where high viral load is present. The questions I have revolve around the scalability and whether the process could be made efficient enough to treat people before they wind up with full blown ARDS and on a ventilator. Can this be scaled up to treat hundreds or thousands of patients in an efficient manner?

The other related question would be, why are these particular patients not able to clear the virus on their own? Does the virus damage the immune system or is there something about their genetics that causes them to be unable to produce their own antibodies?

Even if all it did was rescue people from ventilators and death (and for treating very high risk patients who get infected) that would be huge and certainly scalable, since we're talking only about ~5000 current critical cases in the US. We ought to be able to find 2000 recovered donors for that (usually get 2-3 patients per donor, in theory) or even 5000 if we needed to. And I see no reason why this won't work for less serious patients either as the science of using antibodies to activate the immune system has been proven to work.

This should also be scalable for use as a preventative at least for high risk health care workers and other public-facing workers, as there are already blood banks which gather blood and separate out plasma for use in various infectious disease applications. Now, whether this is scalable to the whole population is something I'm not sure of - I've read that more potent engineered antibodies would likely be more effective, as the antibody plasma infusions may only work for a few months.

https://www.rockefeller.edu/coronavirus/research-program-covid-19-sars-cov-2/
 
  • Like
Reactions: redking
His biggest risk is me in that I greet him with a nice brotherly hug when he arrives.
Actually we were wondering if using a backpack blower to blow grass, leaves and the such around is harmful.
You're right about that risk of the hug, unless you're both 100% isolated from others. With regard to the blower, I really have a hard time thinking there's a risk, especially with tiny viral loads on anything on the ground and UV protection - maybe at most wearing a dust mask and goggles, which you should be doing anyway (fine particulates over years can damage eyesight - nothing to do with viruses - that and protection from projectiles is why I always wear full goggles when cutting grass or blowing leaves).
 
Here's an excerpt from the CNN live feed...

A prestigious scientific panel told the White House last night that research shows coronavirus can be spread not just by sneezes or coughs, but also just by talking, or possibly even just breathing.

NO SHIT??? Isn't this why they have been recommending social distancing????
 
  • Like
Reactions: ldwnmas
You're right about that risk of the hug, unless you're both 100% isolated from others. With regard to the blower, I really have a hard time thinking there's a risk, especially with tiny viral loads on anything on the ground and UV protection - maybe at most wearing a dust mask and goggles, which you should be doing anyway (fine particulates over years can damage eyesight - nothing to do with viruses - that and protection from projectiles is why I always wear full goggles when cutting grass or blowing leaves).
I wonder if we're done as a hugging society, not even sure the handshake will be spared.
 
Even if all it did was rescue people from ventilators and death (and for treating very high risk patients who get infected) that would be huge and certainly scalable, since we're talking only about ~5000 current critical cases in the US. We ought to be able to find 2000 recovered donors for that (usually get 2-3 patients per donor, in theory) or even 5000 if we needed to. And I see no reason why this won't work for less serious patients either as the science of using antibodies to activate the immune system has been proven to work.

This should also be scalable for use as a preventative at least for high risk health care workers and other public-facing workers, as there are already blood banks which gather blood and separate out plasma for use in various infectious disease applications. Now, whether this is scalable to the whole population is something I'm not sure of - I've read that more potent engineered antibodies would likely be more effective, as the antibody plasma infusions may only work for a few months.

https://www.rockefeller.edu/coronavirus/research-program-covid-19-sars-cov-2/

Thanks for the link, looks interesting. I'll have to go through it later.

I'm not sure we need to be able to scale this to every person (though that would be nice), but ideally you at least have it available for those who get sick enough to need to be hospitalized. Get them treated before they have to be put on a ventilator. Those Chinese cases still took a while to resolve, and 2 of the 5 were still on a vent at the time of publication. Even for survivors that's rough and can leave them with long term health problems so that has to be avoided if possible. And people who get bad enough to be on vents often stay on them (and in the hospital) for long periods, which ties up the system for cases that follow.

One of the remaining questions is, what happens later...do these people produce their own antibodies or will they be susceptible to reinfection. So many unknowns...
 
NO SHIT??? Isn't this why they have been recommending social distancing????
Yea but I believe the difference is large droplets vs smaller aerosolized droplets which can travel farther and where a mask being worn by an infected person, especially asymptomatic, can help contain both to some degree.
 
it's also why wearing masks is the sensible thing to do, but the federal authorities are still stopping short of saying so.

Gee... why u think that is? And before u answer... I work in paint & hardware.. We are still open and a big enough store that allows people to come inside and shop... I'm in close contact with customers all day long and wear a basic mask cuz that's the only thing I can breath through...( I try to keep my distance as best I can and only put my mask up when I cant avoid close contact... I NEVER touch my face unless I have either washed my hands or used sanitizer) Masks.... Especially N95.. are in very, very short supply.... People have been hoarding since January... (although if I want an N95 mask, I can ask literally 100 people and 99 will be able to give me at least 1) So sensible??? yes I agree.... But people are NOT being sensible right now!!
 
UV radiation should deactivate the virus quickly, so as long as the area/materials are getting some direct sunlight. Harder to know how long it would be viable on shaded surfaces/materials, but there should also be very, very little virus on lawns and roads and trees/shrubs to begin with, so I think you have one of the safest jobs out there. Just wash your hands frequently with soap and water and you'll likely be fine - your biggest risk is probably getting too close to your clients.

https://www.weforum.org/agenda/2020/03/this-is-how-long-coronavirus-lives-on-surfaces

"For items that are hard to clean, sunshine may be valuable. Leave your shoes outside, soles up, in the sun. Coronaviruses begin degrading quickly in temperatures higher than 56 degrees Celsius, and in direct UV light."


thank you..as we were doing a cleanup today and Rock was blowing leaves and dust and grit, I started to think is he blowing spores of Coronavirus all over me.
 
Martenson has been harping mask use for a while and I agree. May not be perfect but every little but helps. People spew a lot of particles when they sneeze and cough, and even when just talking.

Incidentally, we had a situation up here last week where a woman wearing a mask in a grocery store was harassed and then attacked (punched in the face, robbed) by a group of 4 scum-of-the-earth teens (1 male, 3 female). They were yelling at her "you've got coronavirus" (I don't think she had it, but that's not the point). Fortunately police caught them.

 
Yea but I believe the difference is large droplets vs smaller aerosolized droplets which can travel farther and where a mask being worn by an infected person, especially asymptomatic, can help contain both to some degree.

Social distancing, and coughing/sneezing in your elbow would prevent those smaller droplests from spreading.... Isnt that whats been recomended for the past few weeks?
 
Social distancing, and coughing/sneezing in your elbow would prevent those smaller droplests from spreading.... Isnt that whats been recomended for the past few weeks?
Coughing/sneezing into elbow is good but not everyone does that. And we also know that people who have no coughs or sneezes can spread it too asymptomatically. Social distancing helps all of this but if it can spread in an aerosolized manner with smaller droplets, I think the size of 5 microns one SK Dr. said, then sounds like it can be even more transmissible depending on the circumstance. More reason for the universal facial covering to provide a sort of herd protection.
 
Coughing/sneezing into elbow is good but not everyone does that. And we also know that people who have no coughs or sneezes can spread it too asymptomatically. Social distancing helps all of this but if it can spread in an aerosolized manner with smaller droplets, I think the size of 5 microns one SK Dr. said, then sounds like it can be even more transmissible depending on the circumstance. More reason for the universal facial covering to provide a sort of herd protection.

Not buying this.... I've went days without a mask at store... hundreds of customers per day.. If even 2% were asymptomatic, then it would have shut this store down.... One thing I can say about past few weeks... Where in past years I could easily point out the sick people coming in.... Be impossible to say so now... People who have any recognizable symptoms are at the very least NOT COMING IN....(we offer curbside pickup)… So basically, only the unknowing Asymptomatic would be coming in... I will say this...The amount of people coming in wearing some sort of facemask protection has increased 1000%....2 weeks ago maybe 2% of people coming in wore a mask... now its more like 70%
 


ct thorax of 60 yo single lady - south jersey with hypertension,obesity, metabolic syndrome who gets coughed on by guy in line at shop rite 3 days prior and develops sudden chest pain associated with hacking cough, dyspnea. She was there for her "hunker down" toilet paper, etc.- so there is the irony. treated and released same day at med ctr. today is day 9. some continued night sweats and hacking. classic scan-"ground glass" appearance both lungs.She said "oh shit ' as soon as the guy turned and hacked.
 
Not buying this.... I've went days without a mask at store... hundreds of customers per day.. If even 2% were asymptomatic, then it would have shut this store down.... One thing I can say about past few weeks... Where in past years I could easily point out the sick people coming in.... Be impossible to say so now... People who have any recognizable symptoms are at the very least NOT COMING IN....(we offer curbside pickup)… So basically, only the unknowing Asymptomatic would be coming in... I will say this...The amount of people coming in wearing some sort of facemask protection has increased 1000%....2 weeks ago maybe 2% of people coming in wore a mask... now its more like 70%
Well there’s that patient 31 in SK responsible for 1100+ infections...singing in a choir was one thing she did while infected. Same for a choir in Washington where 45 out of 60 were infected and reports say no outward sickness and no contact. In these clusters you see pop up it seems to have been easily transmissible and I can’t imagine all of them were created by one crazy cougher or sneezer.

Haven’t been out in awhile so glad to hear more are wearing face coverings. It’s good for everyone if that trend continues. Mayors of the two largest cities in the country recommending so hope it catches on.
 
no reason the leagues can't play. It just wont be in front of fans. If I were pro sports league, I would quarantine my teams immediately and looking into a central location to play. No travel, no fans, etc. Keep the players, coaches, umpires, etc in a bubble and play the games all day long. Could have games going in a month. Great tv ratings.

+1. The NBA really dropped the ball (no pun intended) on this. They should restart the season in Vegas. Private planes for each team and key personnel. Privates planes for refs, NBA support and TV stations logistical staff. Every team gets their own separate floor in the fancy Vegas hotels. Get food delivered to rooms 3 or 4 times a day. Team buses to an arena and play with no fans but broadcast it. The ratings would be great with no other sports active.

It could work since rosters are 15 players + 5 coaches/trainers. And there are four legit arenas in Vegas: MGM Grand Garden, T-Mobile Arena, Orleans Arena, and Thomas & Mack. Do temperature checks morning and night, and Covid-19 testing every three days.

Come to think of it, the NCAA could follow this blueprint for the NCAA Tournament. CBS would need to shell out cash to get every school on a private plane and hotel, but then they would have a ton of people watching.
 
  • Like
Reactions: Ridge 22
Well there’s that patient 31 in SK responsible for 1100+ infections...singing in a choir was one thing she did while infected. Same for a choir in Washington where 45 out of 60 were infected and reports say no outward sickness and no contact. In these clusters you see pop up it seems to have been easily transmissible and I can’t imagine all of them were created by one crazy cougher or sneezer.

Haven’t been out in awhile so glad to hear more are wearing face coverings. It’s good for everyone if that trend continues. Mayors of the two largest cities in the country recommending so hope it catches on.

Don't get me wrong... I'm not saying that people shouldn't wear a mask... But I do believe that the general public shouldn't be hoarding the precious N95 masks while the people that really need them go without/or have to reuse worn ones...(for the general public... It should be more about worrying about being Asymptomatic than protecting about getting Covid19... I totally subscribe to Dr. David Price... Wash hands/sanitize often.. DO NOT TOUCH YOUR FACE!!)
 
This is potentially freakin' huge news about the convalescent plasma-antibody treatment approach. Now this is a guy who actually has some results worth screaming to the media about, but he first published it (in JAMA a respected medical journal) and is being circumspect, as he should be, since it was an uncontrolled, unblinded small study, but 5 for 5 with treatment success of people on ventilators is impressive. However, let's wait a week or two and I'm confident we'll see even more good news (this was a Chinese study with technology similar to what they're now using in NYC at Mt Sinai and elsewhere, so should have news from there soon), as this technology should simply just work, like it has in the past. Should also work as a preventative. Seriously crossing fingers.

Findings: In this uncontrolled case series of 5 critically ill patients with COVID-19 and acute respiratory distress syndrome (ARDS), administration of convalescent plasma containing neutralizing antibody was followed by an improvement in clinical status.

Conclusions: In this preliminary uncontrolled case series of 5 critically ill patients with COVID-19 and ARDS, administration of convalescent plasma containing neutralizing antibody was followed by improvement in the patients’ clinical status. The limited sample size and study design preclude a definitive statement about the potential effectiveness of this treatment, and these observations require evaluation in clinical trials.


https://jamanetwork.com/journals/jama/fullarticle/2763983?resultClick=1

https://www.healio.com/hematology-oncology/hematology/news/online/{75453a03-ea98-4c57-8b50-7997853beabe}/convalescent-plasma-transfusion-shows-promise-for-severely-ill-patients-with-covid-19

There will be a vaccine by the end of the year.
 
There will be a vaccine by the end of the year.
Way too late for the current crisis, though and end of the year is a stretch (unless they decide to go with an emergency use approach - which they won't do if the antibody-plasma approach buys us the time we need until we have a fully safe vaccine fully evaluated for safety and efficacy in phase III clinical trials, which is very unlikely to be available before next February. Trust me.
 
Status
Not open for further replies.
ADVERTISEMENT
ADVERTISEMENT